関: allergic bronchopulmonary aspergillosis

WordNet

severe respiratory disease of birds that takes the form of an acute rapidly fatal pneumonia in young chickens and turkeys (同)brooder pneumonia
an opportunistic infection by a fungus of the genus Aspergillus; characterized by inflammation and lesions of the ear and other organs
disease especially in agricultural workers caused by inhalation of Aspergillus spores causing lumps in skin and ears and respiratory organs

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1. アレルギー性気管支肺アスペルギルス症の臨床症状および診断 clinical manifestations and diagnosis of allergic bronchopulmonary aspergillosis
2. アレルギー性気管支肺アスペルギルス症の治療 treatment of allergic bronchopulmonary aspergillosis
3. 慢性肺アスペルギルス症の治療 treatment of chronic pulmonary aspergillosis
4. 好酸球の生物学および好酸球増多症の原因 eosinophil biology and causes of eosinophilia
5. 侵襲性アスペルギルス症の疫学および臨床症状 epidemiology and clinical manifestations of invasive aspergillosis

English Journal

Allergic bronchopulmonary mycosis due to fungi other than Aspergillus: a global overview.

Chowdhary A, Agarwal K, Kathuria S, Gaur SN, Randhawa HS, Meis JF.Author information Department of Medical Mycology , and.AbstractAbstract Allergic bronchopulmonary mycosis (ABPM) is a hypersensitivity-mediated disease of worldwide distribution. We reviewed 143 reported global cases of ABPM due to fungi other than aspergilli. The commonest etiologic agent was Candida albicans, reported in 60% of the cases, followed by Bipolaris species (13%), Schizophyllum commune (11%), Curvularia species (8%), Pseudallescheria boydii species complex (3%) and rarely, Alternaria alternata, Fusarium vasinfectum, Penicillium species, Cladosporium cladosporioides, Stemphylium languinosum, Rhizopus oryzae, C. glabrata, Saccharomyces cerevisiae and Trichosporon beigelii. India accounted for about 47% of the globally reported cases of ABPM, attributed predominantly to C. albicans, followed by Japan (16%) where S. commune predominates, and the remaining one-third from the USA, Australia and Europe. Notably, bronchial asthma was present in only 32% of ABPM cases whereas its association with development of allergic bronchopulmonary aspergillosis (ABPA) is known to be much more frequent. The cases reviewed herein revealed a median IgE value threefold higher than that of ABPA, suggesting that the etiologic agents of ABPM incite a stronger immunological response than that by aspergilli in ABPA. ABPM is currently underdiagnosed, warranting comprehensive basic and clinical studies in order to elucidate its epidemiology and to devise a more effective therapy.
Critical reviews in microbiology.Crit Rev Microbiol.2014 Feb;40(1):30-48. doi: 10.3109/1040841X.2012.754401. Epub 2013 Feb 5.
Abstract Allergic bronchopulmonary mycosis (ABPM) is a hypersensitivity-mediated disease of worldwide distribution. We reviewed 143 reported global cases of ABPM due to fungi other than aspergilli. The commonest etiologic agent was Candida albicans, reported in 60% of the cases, followed by Bipolari
PMID 23383677

SIMIFF study: Italian fungal registry of mold infections in hematological and non-hematological patients.

Montagna MT, Lovero G, Coretti C, Martinelli D, Delia M, De Giglio O, Caira M, Puntillo F, D'Antonio D, Venditti M, Sambri V, Di Bernardo F, Barbui A, Lo Cascio G, Concia E, Mikulska M, Viscoli C, Maximova N, Candoni A, Oliveri S, Lombardi G, Pitzurra L, Sanguinetti M, Masciari R, Santantonio T, Andreoni S, Barchiesi F, Pecile P, Farina C, Viale P, Specchia G, Caggiano G, Pagano L.Author information Hygiene Section, Department of Biomedical Science and Human Oncology, University of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy, mariateresa.montagna@uniba.it.AbstractPURPOSE: We compared the risk factors, the diagnostic tools and the outcome of filamentous fungal infections (FFIs) in hematological patients (HAEs) and non-hematological patients (non-HAEs).
Infection.Infection.2014 Feb;42(1):141-51. doi: 10.1007/s15010-013-0539-3. Epub 2013 Oct 23.
PURPOSE: We compared the risk factors, the diagnostic tools and the outcome of filamentous fungal infections (FFIs) in hematological patients (HAEs) and non-hematological patients (non-HAEs).METHODS: Prospective surveillance (2009-2011) of proven and probable FFIs was implemented in 23 Italian hospi
PMID 24150958

Cerebral aspergillosis in adult critically ill patients: a descriptive report of 10 patients from the AspICU cohort.

Spapen H1, Spapen J2, Taccone FS3, Meersseman W4, Rello J5, Dimopoulos G6, Charles PE7, Rao R8, Pérez M5, Martin C9, Vogelaers D10, Blot SI11; AspICU Study Investigators.Author information 1Intensive Care Department, University Hospital, Vrije Universiteit, Laarbeeklaan 101, B-1090 Brussels, Belgium. Electronic address: herbert.spapen@uzbrussel.be.2General Internal Medicine, Vrije Universiteit, Brussels, Belgium.3Intensive Care Department, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.4Medical Intensive Care Unit, University Hospital Leuven, Leuven, Belgium.5Hospital Universitari Vall d'Hebron, Vall D'Hebron Institute of Research, CIBERES, Universitat Autònoma de Barcelona, Barcelona, Spain.6Department of Critical Care Medicine, Attikon University Hospital, University of Athens Medical School, Athens, Greece.7Service de Réanimation Médicale, Hôpital Bocage Central, C.H.U. Dijon, Dijon University Hospital, Dijon, France.8Department of Microbiology-Infection Prevention and Control, Apollo Hospitals, Hyderabad, India.9Intensive Care Department, Assistance Publique-Hôpitaux de Marseille, Marseille, France.10General Internal Medicine and Infectious Diseases, Ghent University, Ghent, Belgium.11Department of Internal Medicine, Faculty of Medicine and Health Science, Ghent University, Ghent, Belgium.AbstractAn unexpectedly high incidence of invasive pulmonary aspergillosis (IPA) has been reported in non-neutropenic intensive care unit (ICU) patients. After the respiratory tract, the brain is most often affected by invasive aspergillosis. However, little is known about brain involvement by Aspergillus in critically ill patients. In this study, demographics, risk profile, diagnosis, treatment and outcome of proven cases of invasive cerebral aspergillosis (ICA) taken from a cohort of 563 adult patients with evidenced Aspergillus involvement during their ICU stay were reviewed. Ten patients with central nervous system aspergillosis were identified. All had one or more host factors predisposing for invasive aspergillosis. The clinical and radiological presentation was non-specific and exclusively pulmonary-related. All but one patient had proven or probable/putative IPA. On cerebral computed tomography, lesions appeared as either solitary and hyperdense or were multiple and randomly distributed throughout the brain. One patient presented with sole meningeal infestation. Aspergillus infection was confirmed by brain biopsy in three subjects. Voriconazole was used as primary treatment in only one-half of the patients. Mortality was 90%. ICA is not frequently observed in adult ICU patients. Diagnosis must be considered in patients at risk presenting with proven or probable/putative IPA in association with suggestive neuroradiological findings. The brain is most likely affected through haematogenous dissemination from the lungs. Current treatment recommendations are not always applied and outcome remains dismal.
International journal of antimicrobial agents.Int J Antimicrob Agents.2014 Feb;43(2):165-9. doi: 10.1016/j.ijantimicag.2013.10.012. Epub 2013 Nov 15.
An unexpectedly high incidence of invasive pulmonary aspergillosis (IPA) has been reported in non-neutropenic intensive care unit (ICU) patients. After the respiratory tract, the brain is most often affected by invasive aspergillosis. However, little is known about brain involvement by Aspergillus i
PMID 24315314