attenuated strain

弱毒株

WordNet

1. become stretched or tense or taut; "the bodybuilders neck muscles tensed;" "the rope strained when the weight was attached" (同)tense
2. (psychology) nervousness resulting from mental stress; "his responsibilities were a constant strain"; "the mental strain of staying alert hour after hour was too much for him" (同)mental strain, nervous strain
3. (physics) deformation of a physical body under the action of applied forces
4. injury to a muscle (often caused by overuse); results in swelling and pain
5. an intense or violent exertion (同)straining
6. use to the utmost; exert vigorously or to full capacity; "He really extended himself when he climbed Kilimanjaro"; "Dont strain your mind too much" (同)extend
7. become weaker, in strength, value, or magnitude
8. reduced in strength; "the faded tones of an old recording" (同)attenuated, faded, weakened
9. showing signs of mental and emotional tension; "her voice was strained as she asked the question"
10. of an electrical signal; reduced in amplitude with little or no distortion

PrepTutorEJDIC

1. …‘を'『引っ張る』 / (使い過ぎて)〈体など〉‘を'『痛める』,弱める / …‘を'『最大限に働かせる』,精一杯使う / 〈意味・規則など〉‘を'曲げる,こじつける,拡大解釈する / 〈液体〉‘を'『こす』;(液体から)〈固形分〉‘を'こして取る《+『out(off)』+『名』+『from』+『名』》 / 全力を尽くす,懸命に努力する / ぱんと張る / 〈C〉〈U〉『張りつめること』,張る力 / 〈C〉『筋違い』,ねんざ,くじき / 〈U〉(精神的に,極度に)緊張,重荷,過労 / 〈C〉骨のおれる仕事,激務
2. 〈C〉家系,血統,種族 / 〈C〉品種 / 〈U〉《しばしばa ~》(遺伝的な)性質,体質 / 〈C〉《しばしば複数形で》《単数扱い》(音楽の)曲,一節 / 〈C〉口調,言い回し,文体
3. 〈固体など〉'を'細くする;〈体など〉'を'やせさせる / 〈力・価値など〉'を'減じる,弱める
4. 緊張した;疲れた / 不自然な,わざとらしい;こじつけの

UpToDate Contents

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English Journal

• Conditions at the time of inoculation influence survival of attenuated Escherichia coli O157:H7 on field-inoculated lettuce.

• Moyne AL, Blessington T, Williams TR, Koike ST, Cahn MD, Marco ML, Harris LJ.
• Food microbiology. 2020 Feb;85()103274.
• The impact of plant development, environmental conditions at the time of inoculation, and inoculum concentration on survival of attenuated BSL1 Escherichia coli O157:H7 strain ATCC 700728 on field-grown romaine lettuce was evaluated over 3 years. E. coli 700728 was inoculated onto 4- and 6-week-old
• PMID 31500714

• Detection of tumors with fluoromarker-releasing bacteria.

• Panteli JT, Van Dessel N, Forbes NS.
• International journal of cancer. 2020 Jan;146(1)137-149.
• Combining the specificity of tumor-targeting bacteria with the sensitivity of biomarker detection would create a screening method able to detect small tumors and metastases. To create this system, we genetically modified an attenuated strain of Salmonella enterica to release a recombinant fluorescen
• PMID 31093970

• Infectious bronchitis virus Mass-type (GI-1) and QX-like (GI-19) genotyping and vaccine differentiation using SYBR green RT-qPCR paired with melting curve analysis.

• Laconi A, Berends AJ, de Laat ECH, Urselmann TAPMP, Verheije HM.
• Journal of virological methods. 2020 Jan;275()113771.
• Infectious Bronchitis Virus (IBV) is a highly contagious virus of chicken, causing huge economic losses in the poultry industry. Many genotypes circulate in a given area, and optimal protection relies on vaccination with live attenuated vaccines of the same genotype. As these live vaccines are deriv
• PMID 31712091

Japanese Journal

• Oral administration of the probiotic bacterium <i>Lactobacillus acidophilus</i> strain L-55 modulates the immunological parameters of the laying hen inoculated with a Newcastle disease virus-based live attenuated vaccine

• HO THI Dung,HATABU Toshimitsu,SUNADA Yosuke,KONDO Yasuhiro
• Bioscience of Microbiota, Food and Health, 2020
• … strain L-55 (LaL-55) enhances the immune response among chicks exposed to a Newcastle disease virus (NDV)-based live attenuated vaccine. … Oral administration of LaL-55 augmented the elevation in the total numbers of leukocytes and lymphocytes following inoculation with the NDV-based live attenuated vaccine. …
• NAID 130007802638

• Construction and Characterization of a PGN_0297 Mutant of Porphyromonas gingivalis: Evidence of the Contribution of PGN_0297 to Gingipain Activity

• Ono Shintaro,Nakayama Masaaki,Tachibana Masato,Abu Saleh Muhammad Shahriar ,Heling Wang,Takashiba Shogo,Ohara Naoya
• Acta Medica Okayama 73(4), 315-323, 2019-08
• … The mutant ΔPGN_0297 failed to attenuate Akt phosphorylation at Thr308 and Ser473, but both phosphorylations were attenuated in the wild-type and its complementation strain. …
• NAID 120006713034

• 肥満誘導抵抗性ddY個体における脂肪肝抑制および耐糖能正常化機序の解析

• 田邉 由幸,前田 利男,大石 真琴,井村 未来
• 日本薬理学会年会要旨集 92(0), 3-P-092, 2019
• … <p>During repeated preparations of high-fat diet (HFD)-induced obese mice, we have reproducibly observed both obesity-resistant (HFD_lean) and obesity-prone (HFD_fat) subpopulations in ddY mice, an outbred strain. … Hepatic steatosis was attenuated in HFD_lean …
• NAID 130007813258

Related Links

• Attenuated strains in coccidiosis vaccines - Eimeria ...

The non-attenuated vaccines comprise parasites that may have been derived from laboratory or field strains, but have not been modified in any way to change their natural virulence. When chicks are vaccinated with a non-attenuated strain, the initial application is with a relatively low dose of oocysts and should be uniform across the flock.

• Definition of Attenuated

Now "attenuated" refers to procedures that weaken an agent of disease (a pathogen). An attenuated virus is a weakened, less vigorous virus. A vaccine against a viral disease can be made from an attenuated, less virulent strain of

• Attenuated Vaccine - an overview | ScienceDirect Topics

Live attenuated vaccine from the Oka strain is now administered for protection against varicella. Antiviral agents such as acyclovir, famciclovir, and valacyclovir can be used in high-risk patients to decrease morbidity and mortality

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★リンクテーブル★

リンク元	「弱毒株」
関連記事	「strain」「attenuate」「straining」

「弱毒株」

　　[★]

英

attenuated strain

関

ワクチン、生ワクチン

「strain」

　　[★]

• n.

• 強く引っ張られること、張りつめ。極度の緊張、重圧、重荷。酷使。過労
• 懸命の努力、奮闘。
• ひずみ、変形。ひずみ度。筋違い、捻挫。損傷

• vi.

• 引っ張る(at)。(緊張する、(便所で)力む。(～に抗して)力を込める(against)。(歌手が)声を振り絞る

Treatment with bed rest, head elevation, and avoidance of straining is the first step.(外リンパ瘻)(治療の第一歩はベットでの安静、頭部挙上、および力むことを回避することである)

• 懸命につとめる、非常に骨を折る(after, todo)。逡巡する(at)

She is straining to take a breath but can only mouth the phrase: "I can't br-" brefore collapsing.

• ねじれる、狂いを生ずる
• 漉される、しみ通る/出る、したたる

• vt.

　 　 　 　 　 　 　 　

「attenuate」

　　[★]

• vt.

• 捕捉する。薄める。和らげる、弱める。減ずる。(ウイルスなどを)弱毒化する、原毒する。

• vi.

• 細くなる、薄くなる、弱くなる、少なくなる。

関

(n.)attenuation, (adj.)tenuous 非常に薄い、細い。希薄な

　 　 　

「straining」

　　[★]

• n.

• (強い)緊張、重圧、負担。歪める/変形させること

• adj.

• ひどく骨が折れる、試練となる