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Association between apolipoprotein e gene polymorphism and myocardial infarction.

Tanguturi P, Pullareddy B, Sampath Kumar P, Murthy DK.SourceDepartment of Genetics, Osmania University, Hyderabad, 500013, Andhra Pradesh, India, tanguturi2008@gmail.com.
Biochemical genetics.Biochem Genet.2013 Jun;51(5-6):398-405. doi: 10.1007/s10528-013-9572-2. Epub 2013 Jan 31.
We investigated apolipoprotein E (APOE) genotypic influence on myocardial infarction risk in South India, where the disease is emerging as a major threat to the public health care system. The study included 412 subjects: 202 myocardial infarction patients and 210 age- and sex-matched controls. DNA w
PMID 23371373

MRI of carriers of the apolipoprotein E e4 allele-evidence for structural differences in normal-appearing brain tissue in e4+ relative to e4- young adults.

Dowell NG, Ruest T, Evans SL, King SL, Tabet N, Tofts PS, Rusted JM.SourceBrighton and Sussex Medical School (BSMS), Clinical Imaging Sciences Centre, Brighton, Sussex, UK.
NMR in biomedicine.NMR Biomed.2013 Jun;26(6):674-82. doi: 10.1002/nbm.2912. Epub 2013 Jan 31.
Apolipoprotein E is a protein involved in cholesterol and lipid transport. The gene coding for this protein has three different alleles: e2, e3 and e4. The e4 allele is recognised as a significant risk factor for the development of Alzheimer's disease in later life. Paradoxically, behavioural and fu
PMID 23364916

Binding and Repressive Activities of Apolipoprotein E3 and E4 Isoforms on the Human ApoD Promoter.

Levros LC Jr, Labrie M, Charfi C, Rassart E.SourceLaboratoire de biologie moléculaire, Département des Sciences Biologiques, and BioMed, centre de recherches biomédicales, Université du Québec à Montréal, Montréal, Québec, Canada.
Molecular neurobiology.Mol Neurobiol.2013 May 30. [Epub ahead of print]
Apolipoprotein D (ApoD) gene expression is increased in several neurological disorders such as Alzheimer's disease (AD) and multiple sclerosis. We previously showed that transgenic mice that overexpress human ApoD show a better resistance against paraquat or OC43 coronavirus-induced neurodegeneratio
PMID 23715769

Lipoprotein glomerulopathy-like disease in a patient with type III hyperlipoproteinemia due to apolipoprotein E2 (Arg158 Cys)/3 heterozygosity

KARUBE Miho,NAKABAYASHI Kimimasa,FUJIOKA Yasunori,YOSHIHARA Ken,YAMADA Akira,MATSUNAGA Akira,SAITO Takao
Clinical and experimental nephrology 11(2), 174-179, 2007-06-01
NAID 10024140656

Effect of Apolipoprotein E Genotype on Association of Menopausal Status with Lipid Level in Japanese Women

Yamanouchi Yasuko,Hashimoto Hideki,Yamaoka Kazue,Takano Takako,Kisaki Tomonari,Oku Junji,Yano Eiji
Journal of health science 52(5), 532-539, 2006-10-01
… In Caucasians, changes in lipid level after menopause across apolipoprotein E (apo E) genotypes were studied. … Apo E2 [APOE, R158C] carriers in the senium period had a lower LDL-cholesterol level than those in the fertile period (81.5±12.0 mg/dl vs. 122.3±12.9 mg/dl). …
NAID 110004809607