English Journal

The delta-opioid receptor and Parkinson's disease.

Huang JZ, Ren Y, Xu Y, Chen T, Xia TC, Li ZR, Zhao JN, Hua F, Sheng SY, Xia Y.
CNS neuroscience & therapeutics. 2018 12;24(12)1089-1099.
Parkinson's disease (PD) is a common degenerative neurological disease leading to a series of familial, medical, and social problems. Although it is known that the major characteristics of PD pathophysiology are the dysfunction of basal ganglia due to injury/loss of dopaminergic neurons in the subst
PMID 30076686

Evaluation of the antiparkinsonism and neuroprotective effects of hydrogen sulfide in acute 6-hydroxydopamine-induced animal model of Parkinson's disease: behavioral, histological and biochemical studies.

Sarukhani M, Haghdoost-Yazdi H, Sarbazi Golezari A, Babayan-Tazehkand A, Dargahi T, Rastgoo N.
Neurological research. 2018 Jul;40(7)523-531.
Studies have shown that hydrogen sulfide (HS), a gaseous neurotransmitter, has neuroprotective effect. Here, we evaluated the neuroprotective activity of HS in acute 6-hydroxydopamine (6-OHDA) animal model of Parkinson's disease (PD). 6-OHDA was injected through stereotaxic surgery into medial foreb
PMID 29726751

Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia.

Bergman H, Rathbone J, Agarwal V, Soares-Weiser K.
The Cochrane database of systematic reviews. 2018 02;2()CD000459.
Since the 1950s antipsychotic medication has been extensively used to treat people with chronic mental illnesses such as schizophrenia. These drugs, however, have also been associated with a wide range of adverse effects, including movement disorders such as tardive dyskinesia (TD) - a problem often
PMID 29409162

Japanese Journal

抗パーキンソン薬の新しい使い方--気分障害への効果 (特集向精神薬の新しい使い方)

井上猛,北市雄士,田中輝明 [他]
精神科 11(5), 350-355, 2007-11
NAID 40015727938

DETERMINATION OF TRIHEXYPHENIDYL IN BODY FLUIDS BY GAS CHROMATOGRAPHY WITH SURFACE IONIZATION DETECTION

Ishii Akira,Nishikawa Masanobu,Seno Hiroshi,Kumazawa Takeshi,Watanabe Kanako,Suzuki Osamu
法中毒 = Japanese journal of forensic toxicology 12(3), 241-246, 1994-09-15
… Trihexyphenidyl (benzhexol, Artane®), a well known antiparkinsonism drug, could be detected with high sensitivity by gas chromatography with surface ionization detection (GC-SID) using diphenylpyraline as internal standard. …
NAID 120005314010

直接試料導入‐化学イオン化マスクロマトグラフィーによる薬物中毒の緊急検査法

村田武 [他],中村順子,島田力,沢辺善之
分析化学 34(6), 329-334, 1985
直接試料導入を用い,イソブタンを試薬ガスとした化学イオン化質量分析法で催眠薬,鎮痛薬,向精神薬,抗パーキンソン氏病薬などによる急性中毒診断のために,確実かつ迅速な同定法について述べる.使用した17種類の薬物の化学イオン化(CI)マススペクトルはプロムワレリル尿素を除いて,MH<SUP>+</SUP>イオンのほとんどがベースピークとなり,質量を読み取るだけで同定できた.しかし …
NAID 110002909180

Related Links

Antiparkinson Drugs | definition of Antiparkinson Drugs by ...

Antiparkinson Drugs: Definition Antiparkinson drugs are medicines that relieve the symptoms of Parkinson's disease and other forms of parkinsonism. Purpose Antiparkinson drugs are used to treat symptoms of parkinsonism, a group of disorders that share four main symptoms: tremor or trembling in the hands, arms, legs, jaw, and face; stiffness or ...

Antiparkinson drug | Britannica

Antiparkinson drug, any drug used to treat the symptoms of Parkinson disease or other conditions of parkinsonism.The major antiparkinson drugs are levodopa, dopamine-receptor agonists, amantadine, and the so-called COMT (catechol-O-methyltransferase) inhibitors, MAO-B (monoamine oxidase B) inhibitors, and muscarinic receptor antagonists.

List of Antiparkinson agents - Generics Only - Drugs.com

Antiparkinson agents aim to replace dopamine either by drugs that release dopamine or those that mimic the action of dopamine. Parkinson's disease is a degenerative disorder of movement that occurs due to dopamine deficiency in the basal ganglia. ...