WordNet

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/12/11 10:17:25」(JST)

Look up antidiarrhoeal in Wiktionary, the free dictionary.

An anti-diarrhoeal drug (or anti-diarrheal drug in American English) is any medication which provides symptomatic relief for diarrhoea.

Electrolyte solutions are used to replace lost fluids and salts in acute cases.
Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
Absorbents absorb toxic substances that cause infective diarrhoea, methylcellulose is an absorbent.
Anti-inflammatory solutions like bismuth subsalicylate.
Opioids' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have agonist actions on the intestinal opioid receptors, which when activated cause constipation. Drugs such as morphine or codeine can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is loperamide which is only an agonist of the μ opioid receptors in the large intestine and does not have opioid affects in the central nervous system as it doesn't cross the blood–brain barrier in significant amounts. This enables loperamide hydrochloride to be used to the same benefit as other opioid drugs but without the CNS side effects or potential for abuse.

Mutschler, Ernst; Schäfer-Korting, Monika (2001). Arzneimittelwirkungen (in German) (8 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. pp. 652–4. ISBN 3-8047-1763-2.

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Rajan S, Suganya H, Thirunalasundari T, Jeeva S.SourceDepartment of Microbiology, M. R. Govt Arts College, Mannargudi-614 001, Thiruvarur District, Tamilnadu, India.
Asian Pacific journal of tropical medicine.Asian Pac J Trop Med.2012 Aug;5(8):630-3.
OBJECTIVE: To examine the antidiarrhoeal activity of alcoholic and aqueous seed kernel extract of Mangifera indica (M. indica) on castor oil-induced diarrhoeal activity in Swiss albino mice.METHODS: Mango seed kernels were processed and extracted using alcohol and water. Antidiarrhoeal activity of t
PMID 22840451

Assessment of the antidiarrhoeal properties of the aqueous extract, the 80% methanol extract and its soluble fractions of the leaves of Alstonia congensis Engl. (Apocynaceae) in Wistar rats.

Nsaka Lumpu S, Tona Lutete G, Kambu Kabangu O, Cimanga Kanyanga R, Apers S, Pieters L, Vlietinck AJ.SourceFaculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa XI, Democratic Republique of Congo.
Journal of ethnopharmacology.J Ethnopharmacol.2012 Aug 1;142(3):620-6. Epub 2012 May 15.
AIM OF THE STUDY: To evaluate the antidiarrhoeal properties of Alstonia congensis leaves claimed to be effective for the treatment of diarrhoea by traditional healers during our ethnopharmacological investigation conducted in Kinshasa, Democratic Republic of Congo.MATERIALS AND METHODS: The aqueous
PMID 22609154