- 関
- antidiarrheal、antidiarrheal agent、antidiarrheal drug、antiperistaltic、antipropulsive
WordNet
- a drug used to control or stop diarrhea (同)antidiarrheal_drug
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/04/08 19:10:46」(JST)
[Wiki en表示]
An anti-diarrhoeal drug (or anti-diarrheal drug in American English) is any medication which provides symptomatic relief for diarrhoea.
Types
- Electrolyte solutions are used to replace lost fluids and salts in acute cases.
- Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
- Absorbents absorb toxic substances that cause infective diarrhoea, methylcellulose is an absorbent.
- Anti-inflammatory solutions like bismuth subsalicylate.
- Opioids' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have agonist actions on the intestinal opioid receptors, which when activated cause constipation. Drugs such as morphine or codeine can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is loperamide which is only an agonist of the μ opioid receptors in the large intestine and does not have opioid affects in the central nervous system as it doesn't cross the blood–brain barrier in significant amounts. This enables loperamide hydrochloride to be used to the same benefit as other opioid drugs but without the CNS side effects or potential for abuse.
See also
- ATC code A07 Antidiarrheals, intestinal anti-inflammatory/anti-infective agents
References
- Mutschler, Ernst; Schäfer-Korting, Monika (2001). Arzneimittelwirkungen (in German) (8 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. pp. 652–4. ISBN 3-8047-1763-2.
Antidiarrheals, intestinal anti-inflammatory/anti-infective agents (A07)
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Rehydration |
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Intestinal anti-infectives |
- Antibiotics
- Amphotericin B
- Colistin
- Fidaxomicin
- Kanamycin
- Natamycin
- Neomycin
- Nystatin
- Paromomycin
- Polymyxin B
- Rifaximin
- Streptomycin
- Vancomycin
- Sulfonamides
- Phthalylsulfathiazole
- Succinylsulfathiazole
- Sulfaguanidine
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Intestinal adsorbents |
- Charcoal
- Bismuth
- Pectin
- Kaolin
- Crospovidone
- Attapulgite
- Diosmectite
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Antipropulsives (opioids) |
- Opium tincture (laudanum)
- Codeine
- Morphine
- Camphorated opium tincture (paregoric)
- crosses BBB: Diphenoxylate (Diphenoxylate/atropine)
- Difenoxin
- does not cross BBB: Loperamide
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Intestinal anti-inflammatory agents |
- corticosteroids acting locally
- Prednisolone
- Hydrocortisone
- Prednisone
- Betamethasone
- Tixocortol
- Budesonide
- Beclometasone
- antiallergic agents, excluding corticosteroids
- aminosalicylic acid and similar agents
- Sulfasalazine
- Mesalazine
- Olsalazine
- Balsalazide
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Antidiarrheal micro-organisms |
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Other antidiarrheals |
- Albumin tannate
- Ceratonia
- Crofelemer
- Octreotide
- Racecadotril
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anat (t, g, p)/phys/devp/enzy
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noco/cong/tumr, sysi/epon
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proc, drug (A2A/2B/3/4/5/6/7/14/16), blte
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UpToDate Contents
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English Journal
- Diagnostic performance and therapeutic consequence of thromboelastometry activated by kaolin versus a panel of specific reagents.
- Larsen OH, Fenger-Eriksen C, Christiansen K, Ingerslev J, Sorensen B.SourceCentre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby, Denmark.
- Anesthesiology.Anesthesiology.2011 Aug;115(2):294-302.
- BACKGROUND: Thromboelastography/metry (TEGR; Haemoscope, Niles, IL/ROTEMR; Tem International GmbH, Munich, Germany) is increasingly used to guide transfusion therapy. This study investigated the diagnostic performance and therapeutic consequence of using kaolin-activated whole blood compared with
- PMID 21691196
- Purification and characterization of Aspergillus terreus α-galactosidases and their use for hydrolysis of soymilk oligosaccharides.
- Ferreira JG, Reis AP, Guimaraes VM, Falkoski DL, Fialho Lda S, de Rezende ST.SourceDepartamento de Bioquimica e Biologia Molecular, Universidade Federal de Vicosa, 36.570-000 Vicosa, Minas Gerais, Brazil.
- Applied biochemistry and biotechnology.Appl Biochem Biotechnol.2011 Aug;164(7):1111-25. Epub 2011 Feb 18.
- α-Galactosidases has the potential to hydrolyze α-1-6 linkages in raffinose family oligosaccharides (RFO). Aspergillus terreus cells cultivated on wheat bran produced three extracellular forms of α-galactosidases (E1, E2, and E3). E1 and E2 α-galactosidases presented maximal activities at pH 5,
- PMID 21331589
Japanese Journal
- 寺島 千賀子,高島 正三,中野 孝志,沢井 とし,今井 一洋
- 病院薬学 14(3), 215-222, 1988-06-20
- … 23 kinds of drugs (e.g., vitamins, anti-ulcer drugs, digestants, antacids, purgatives and antidiarrheals) which may be admixed with Ferromia^<[○!R]> …
- NAID 110001798540
Related Links
- Learn how to safely take over-the-counter antidiarrheals.
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- antidiarrheal agent、antidiarrheal drug、antidiarrheals、antidiarrheic、antidiarrhoeal、antipropulsive