WordNet

of critical importance and consequence; "an acute (or critical) lack of research funds"
having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
of an angle; less than 90 degrees
excitement and elation beyond the bounds of sobriety; "the intoxication of wealth and power"

PrepTutorEJDIC

(先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
酔い,酩酊(めいてい) / 夢中,陶酔

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Drinking patterns of alcohol intoxicated adolescents in the emergency department: A latent class analysis.

Diestelkamp S1, Kriston L2, Arnaud N3, Wartberg L4, Sack PM5, Härter M6, Thomasius R7.
Addictive behaviors.Addict Behav.2015 Nov;50:51-9. doi: 10.1016/j.addbeh.2015.06.009. Epub 2015 Jun 11.
INTRODUCTION: The increasing number of children and adolescents in need of emergency medical treatment following acute alcohol intoxication has been a major public health concern in Europe in recent years. However, little is known about drinking habits and associated risks in this population. To our
PMID 26101078

Out-of-hospital cardiac arrest after acute cocaine intoxication associated with Brugada ECG patterns: Insights into physiopathologic mechanisms and implications for therapy.

El Mazloum R1, Snenghi R1, Zorzi A1, Zilio F1, Dorigo A2, Montisci R3, Corrado D1, Montisci M4.
International journal of cardiology.Int J Cardiol.2015 Sep 15;195:245-9. doi: 10.1016/j.ijcard.2015.04.249. Epub 2015 May 1.
PMID 26048386

Male adolescent rats display blunted cytokine responses in the CNS after acute ethanol or lipopolysaccharide exposure.

Doremus-Fitzwater TL1, Gano A2, Paniccia JE2, Deak T2.
Physiology & behavior.Physiol Behav.2015 Sep 1;148:131-44. doi: 10.1016/j.physbeh.2015.02.032. Epub 2015 Feb 21.
Alcohol induces widespread changes in cytokine expression, with recent data from our laboratory having demonstrated that, during acute ethanol intoxication, adult rats exhibit consistent increases in interleukin (IL)-6 mRNA expression in several brain regions, while showing reductions in IL-1 and TN
PMID 25708278

伊藤康,伊藤万由里,向平暁子,浦野真理,近藤絵里,柳垣繁,大澤眞木子,ITO Yasushi,ITO Mayuri,MUKAHIRA Kyoko,URANO Mari,KONDO Eri,YANAGAKI Shigeru,OSAWA Makiko
東京女子医科大学雑誌 83(E1), E395-E398, 2013-01-31
けいれん重積、意識障害、呼吸不全にて入院した5ヵ月の男児。著明な低N a血症と代謝性アシドーシス、頭部C T上脳浮腫を認めた。臨床症状は速やかに改善したが、詳細な問診により、父親が児の夜泣きを鎮めるために浴槽につけた事実と、同行為による日常的虐待が判明した。患児の両親に基本的な育児知識の不足がある点を除いてごく一般的な核家族であり、このような家庭でも虐待にあたるエピソードが起こる可能性が示唆された …
NAID 110009559420

外山耕太郎,佐藤成,田原研一 [他],神保貴宏,村上博和,野島美久,塚本憲史,Toyama Kohtaro,Sato Naru,Tahara Kenichi,Jinbo Takahiro,Murakami Hirokazu,Nojima Yoshihisa,Tsukamoto Norifumi
北関東医学 62(4), 419-422, 2012
ヒ素は腹部症状,多発神経炎,ときに中枢神経症状などの急性中毒をきたす重金属として知られている.Arsenic trioxide(ATO)療法は再発・難治性の急性前骨髄球性白血病(APL)に対して有効な治療法で,その副作用の多くはコントロール可能である.我々はAPL再発に対してATO単独療法施行後に昏睡状態となった症例を経験した.ATO投与の副作用として中枢神経症状は非常にまれで,これまでに意識変容 …
NAID 130003339151

A Case of Epirubicin-Associated Cardiotoxicity Progressing to Life-Threatening Heart Failure and Splenic Thromboembolism

Okura Yuji,Kawasaki Takashi,Kanbayashi Chizuko,Sato Nobuaki
Internal Medicine 51(11), 1355-1360, 2012
… We present the case of a 42-year-old Japanese woman who developed acute heart failure after chemotherapy with epirubicin for breast cancer. … This case report demonstrates that epirubicin-associated cardiotoxicity causes life-threatening heart failure and supportive care is important until the patient recovers from acute intoxication. …
NAID 130002062121