エトポシド
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English Journal
- Anti-inflammatory and anticancer drugs from nature.
- Orlikova B, Legrand N, Panning J, Dicato M, Diederich M.SourceLaboratoire de Biologie Moléculaire et Cellulaire du Cancer, Fondation de Recherche Cancer et Sang, Hôpital Kirchberg, 9, rue Edward Steichen, L-2540, Luxembourg, Luxembourg.
- Cancer treatment and research.Cancer Treat Res.2014;159:123-43. doi: 10.1007/978-3-642-38007-5_8.
- Over the centuries, plant extracts have been used to treat various diseases. Until now, natural products have played an important role in anticancer therapy as there are more than 500 compounds from terrestrial and marine plants or microorganisms, which have antioxidant, antiproliferative, or antian
- PMID 24114478
- Structural studies of several clinically important oncology drugs in complex with human serum albumin.
- Wang ZM, Ho JX, Ruble JR, Rose J, Rüker F, Ellenburg M, Murphy R, Click J, Soistman E, Wilkerson L, Carter DC.SourceNew Century Pharmaceuticals, Inc., 895 Martin Road, Suite C, Huntsville, AL 35824, USA.
- Biochimica et biophysica acta.Biochim Biophys Acta.2013 Dec;1830(12):5356-74. doi: 10.1016/j.bbagen.2013.06.032. Epub 2013 Jul 6.
- BACKGROUND: Serum albumin is a major pharmacokinetic effector of drugs. To gain further insight into albumin binding chemistry, the crystal structures of six oncology agents were determined in complex with human serum albumin at resolutions of 2.8 to 2.0Å: camptothecin, 9-amino-camptothecin, etopos
- PMID 23838380
- Differential effect of hypoxia on etoposide-induced DNA damage response and p53 regulation in different cell types.
- Sermeus A, Rebucci M, Fransolet M, Flamant L, Desmet D, Delaive E, Arnould T, Michiels C.SourceLaboratory of Biochemistry and Cellular Biology (URBC), NARILIS, University of Namur, Namur, Belgium.
- Journal of cellular physiology.J Cell Physiol.2013 Dec;228(12):2365-76. doi: 10.1002/jcp.24409.
- Among the main causes of cancer cell resistance to chemotherapy are p53 mutation and hypoxic tumor microenvironment. However, the effect of hypoxia can be very different from one cell type to the other. We studied the effect of hypoxia on the etoposide-induced cell death in two cancer cell lines, He
- PMID 23702906
Related Links
- Detailed drug Information for Vepesid. Includes common brand names, drug descriptions, warnings, side effects and dosing information. ... Intravenous route(Solution) Severe myelosuppression with resulting infection or bleeding may ...
- Accurate, FDA approved VePesid information for healthcare professionals and patients - brought to you by Drugs.com. ... Warnings VePesid (etoposide) should be administered under the supervision of a qualified physician ...
Related Pictures
★リンクテーブル★
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- 英
- etoposide
- 同
- VP-16, VePesid
- 商
- ベプシド、ラステット
- 関
- 抗悪性腫瘍薬、トポイソメラーゼII阻害剤
- S期とG2期に特異的に作用
- トポイソメラーゼIIによるDNA鎖切断を阻害し、DNA合成を阻害
添付文書
- http://www.info.pmda.go.jp/go/pack/4240403A2050_1_03/4240403A2050_1_03?view=body
参考
- http://www.genome.jp/dbget-bin/www_bget?dr_ja:D00125
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エトポシド VP-16, VePesid