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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/19 16:41:49」(JST)

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1. 軟部および骨肉腫の病原因子 pathogenetic factors in soft tissue and bone sarcomas
2. 晩発性皮膚ポルフィリン症および肝骨髄性ポルフィリン症：臨床的特徴および診断 porphyria cutanea tarda and hepatoerythropoietic porphyria clinical manifestations and diagnosis

Evaluation of toxicological biomarkers in secreted proteins of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and their expressions in the plasma of rats and incineration workers.

Phark S1, Park SY2, Chang YS3, Choi S1, Lim JY1, Kim Y1, Seo JB4, Jung WW5, Sul D6.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 May;1864(5):584-93. doi: 10.1016/j.bbapap.2016.02.018. Epub 2016 Feb 24.
Toxicological biomarkers of 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) were investigated in proteins secreted by HepG2 cells and their expression levels were determined in the plasma of rats exposed to 2,3,7,8-TCDD and in the plasma of incineration workers exposed to dioxins. HepG2 cells wer
PMID 26923389

Aryl hydrocarbon receptor deletion in cerebellar granule neuron precursors impairs neurogenesis.

Dever DP1, Adham ZO1, Thompson B1, Genestine M2, Cherry J3, Olschowka JA4, DiCicco-Bloom E2, Opanashuk LA1.
Developmental neurobiology.Dev Neurobiol.2016 May;76(5):533-50. doi: 10.1002/dneu.22330. Epub 2015 Aug 17.
The aryl hydrocarbon receptor (AhR) is a ligand-activated member of the basic-helix-loop-helix/PER-ARNT-SIM(PAS) transcription factor superfamily that also mediates the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Increasing evidence suggests that AhR influences the development of many ti
PMID 26243376

Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells.

Joiakim A1, Mathieu PA1, Shelp C1, Boerner J1, Reiners JJ Jr2.
Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2016 May;44(5):665-71. doi: 10.1124/dmd.115.066274. Epub 2016 Mar 7.
CYP1A1andCYP1A2are transcriptionally activated in the human normal breast epithelial cell line MCF10A following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Shifting MCF10A cultures to medium deficient in serum and epidermal growth factor (EGF) caused rapid reductions in the activated (i.
PMID 26953171

Levels of polychlorinated dibenzodioxins and polychlorinated dibenzofurans in breast milk samples from three dioxin-contaminated hotspots of Vietnam

Manh Ho Dung,Kido Teruhiko,Tai Pham The,Okamoto Rie,Honma Seijiro,Liang Sun Xian,Anh Le Thai,Maruzeni Shoko,Nghi Tran Ngoc,Nishijo Muneko,Nakagawa Hideaki,Nhu Dang Duc,Tung Dao Van,Hung Nguyen Ngoc,Son Le Ke
Science of the Total Environment 511, 416-422, 2015-04-01
… Breast milk samples from Bien Hoa City, where residents live very close to the air base, showed high levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), with 18% of the samples containing >. … TCDD/g lipid. … However, Phu Cat residents lived far from the air base and their samples showed lower TCDD levels, with none containing >. … TCDD/g lipid. … In Da Nang, TCDD levels in mothers from Thanh Khe (close to the air base, n. …
NAID 120005537894

Immunohistochemical analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity on the developmental dentate gyrus and hippocampal fimbria in fetal mice

KOBAYASHI Yoshihiro,HIRANO Tetsushi,OMOTEHARA Takuya,HASHIMOTO Rie,UMEMURA Yuria,YUASA Hideto,MASUDA Natsumi,KUBOTA Naoto,MINAMI Kiichi,YANAI Shogo,ISHIHARA-SUGANO Mitsuko,MANTANI Youhei,YOKOYAMA Toshifumi,KITAGAWA Hiroshi,HOSHI Nobuhiko
Journal of Veterinary Medical Science advpub(0), 2015
… Behavioral and cognitive functions are impaired by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure. … TCDD exerts its toxicity via the aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor. … The hippocampus, which plays important roles in episodic memory and spatial function, is considered vulnerable to TCDD-induced neurotoxicity, because it contains the AhR. …
NAID 130005077865

Disruption of paired-associate learning in rat offspring perinatally exposed to dioxins

Kakeyama Masaki,Endo Toshihiro,Zhang Yan,Miyazaki Wataru,Tohyama Chiharu
Archives of Toxicology 88(3), 789-798, 2014-03
… Pregnant Long-Evans rats were dosed by gavage with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) at a dose of 0, 200, or 800 ng/kg (referred as Control, TCDD-200, TCDD-800, TBDD-200, or TBDD-800, hereafter) on gestational day 15, and the offspring was tested during adulthood. …
NAID 120005438861