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1. ステージII大腸癌切除後患者に対する補助化学療法adjuvant chemotherapy for resected stage ii colon cancer [show details]
…in stage II (node-negative) disease are less certain, and the use of chemotherapy in this group is variable. This topic review will cover adjuvant therapy for patients with resected stage II colon cancer …
2. クリグラー・ナジャー症候群crigler najjar syndrome [show details]
…more difficult problem is the distinction between Crigler-Najjar syndromes type I and II. As a general rule, type II is associated with lower serum bilirubin concentrations although values can overlap with …
3. メタボリックシンドローム（インスリン抵抗性症候群またはシンドロームX）the metabolic syndrome insulin resistance syndrome or syndrome x [show details]
…There are conflicting data on whether angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs) used to treat hypertension in type 2 diabetes may also help to reduce insulin…
4. バッドキアリ症候群の病因etiology of the budd chiari syndrome [show details]
…G1691A factor V (Leiden) gene mutation, which produces activated protein C resistance G20210A factor II gene mutation Antiphospholipid syndrome Antithrombin deficiency Protein C deficiency Protein …
5. リンチ症候群（遺伝性非ポリポーシス大腸癌）：臨床的特徴および診断lynch syndrome hereditary nonpolyposis colorectal cancer clinical manifestations and diagnosis [show details]
…subsequently modified to include other Lynch syndrome-associated malignancies. According to the Amsterdam II criteria, Lynch syndrome should be suspected in kindreds that meets all of the following criteria: …

English Journal

Diets rich in whole grains increase betainized compounds associated with glucose metabolism.

Kärkkäinen O, Lankinen MA, Vitale M, Jokkala J, Leppänen J, Koistinen V, Lehtonen M, Giacco R, Rosa-Sibakov N, Micard V, Rivellese AAA, Schwab U, Mykkänen H, Uusitupa M, Kolehmainen M, Riccardi G, Poutanen K, Auriola S, Hanhineva K.
The American journal of clinical nutrition. 2018 Nov;108(5)971-979.
Epidemiologic evidence suggests that diets rich in whole grains are associated with a reduced risk of developing chronic diseases and all-cause mortality. However, the molecular mechanisms behind these beneficial metabolic effects are poorly understood. Our aim was to investigate novel trimethylated
PMID 30256894

Intensive dietary intervention promoting the Mediterranean diet in people with high cardiometabolic risk: a non-randomized study.

Grimaldi M, Ciano O, Manzo M, Rispoli M, Guglielmi M, Limardi A, Calatola P, Lucibello M, Pardo S, Capaldo B, Riccardi G.
Acta diabetologica. 2018 Mar;55(3)219-226.
Mediterranean diet (MD) is acknowledged to exert a number of beneficial health effects. We assessed the efficacy and the durability of a 3-month intensive dietary intervention aimed at implementing the MD on body weight and cardiometabolic risk factors in subjects at high risk. One hundred and sixte
PMID 29218417

A systematic review on the relations between pasta consumption and cardio-metabolic risk factors.

Huang M, Li J, Ha MA, Riccardi G, Liu S.
Nutrition, metabolism, and cardiovascular diseases : NMCD. 2017 Nov;27(11)939-948.
The traditional Italian dish pasta is a major food source of starch with low glycemic index (GI) and an important low-GI component of the Mediterranean diet. This systematic review aimed at assessing comprehensively and in-depth the potential benefit of pasta on cardio-metabolic disease risk factors
PMID 28954707