PtdIns 3-kinase

• ホスファチジルイノシトール-3-キナーゼ

関

1-phosphatidylinositol 3-kinase、phosphatidylinositol 3-kinase、PI 3-kinase、PI-3 kinase、PI-3K、PI3-kinase

WordNet

1. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
2. the basic unit of money in Papua New Guinea

UpToDate Contents

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• 1. 未分化リンパ腫キナーゼ（ALK）融合癌遺伝子陽性非小細胞肺癌 anaplastic lymphoma kinase alk fusion oncogene positive non small cell lung cancer
• 2. ホスホリラーゼbキナーゼ欠損症 phosphorylase b kinase deficiency
• 3. ホスホグリセリン酸キナーゼ欠損症およびホスホグリセリン酸ムターゼ欠損症 phosphoglycerate kinase deficiency and phosphoglycerate mutase deficiency
• 4. T細胞受容体シグナル伝達 t cell receptor signaling
• 5. 複合免疫不全 combined immunodeficiencies

English Journal

• Differential Regulatory Functions of Three Classes of Phosphatidylinositol and Phosphoinositide 3-Kinases in Autophagy.

• Yu X1, Long YC, Shen HM.
• Autophagy.Autophagy.2015 May 27:0. [Epub ahead of print]
• Autophagy is an evolutionarily conserved and exquisitely regulated self-eating cellular process with important biological functions. Phosphatidylinositol 3-kinases (PtdIns3Ks) and phosphoinositide 3-kinases (PI3Ks) are involved in the autophagic process. Here we aim to recapitulate how 3 classes of
• PMID 26018563

• Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis.

• Ikonomov OC1, Sbrissa D1, Venkatareddy M2, Tisdale E3, Garg P2, Shisheva A4.
• Biochimica et biophysica acta.Biochim Biophys Acta.2015 May;1853(5):1240-50. doi: 10.1016/j.bbamcr.2015.01.008. Epub 2015 Jan 22.
• The evolutionarily conserved PIKfyve, which synthesizes PtdIns5P from PtdIns, and PtdIns(3,5)P2 from PtdIns3P, requires PtdIns3P as both an enzyme substrate and a membrane recruitment signal. Whereas the PtdIns3P source is undetermined, class III PI3K (Vps34), the only evolutionarily conserved of th
• PMID 25619930

• Yeast-based methods to assess PTEN phosphoinositide phosphatase activity in vivo.

• Rodríguez-Escudero I1, Fernández-Acero T2, Bravo I3, Leslie NR4, Pulido R5, Molina M6, Cid VJ7.
• Methods (San Diego, Calif.).Methods.2015 May;77-78:172-9. doi: 10.1016/j.ymeth.2014.10.020. Epub 2014 Oct 25.
• The PTEN phosphoinositide 3-phosphatase is a tumor suppressor commonly targeted by pathologic missense mutations. Subject to multiple complex layers of regulation, its capital role in cancer relies on its counteracting function of class I phosphoinositide 3-kinase (PI3K), a key feature in oncogenic
• PMID 25448481

Japanese Journal

• Atg14, a key player in orchestrating autophagy

• International Journal of Cell Biology 2011, 2011
• NAID 120003878522

• PtdIns 3-Kinase Orchestrates Autophagosome Formation in Yeast

• Journal of Lipids 2011, 1-9, 2011
• NAID 120002989254

• Dynamics and function of PtdIns(3)P in autophagy.

• Autophagy 4(7), 952-954, 2008-10-01
• NAID 120003005576

Related Links

• CiNii 論文 - PtdIns 3-Kinase Orchestrates Autophagosome ...

Phosphorylation of phosphatidylinositol (PtdIns) by a PtdIns 3-kinase, Vps34, is a key step in coordinating Atg proteins and lipid molecules. Vps34 forms two distinct protein complexes, only one of which is involved in generating ...

• Plant PtdIns 3-Kinase Goes Nuclear - The Plant Cell

Plant PtdIns 3-Kinase Goes Nuclear Phosphoinositides are dynamic and vital members of the cell’s repertoire of signaling molecules. ...

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★リンクテーブル★

リンク元	「PI3-kinase」「PI 3-kinase」「PI-3K」「ホスファチジルイノシトール-3-キナーゼ」「1-phosphatidylinositol 3-kinase」
関連記事	「PtdIns」「kinase」

「PI3-kinase」

　　[★]

ホスファチジルイノシトール3キナーゼ、ホスホイノシチド3キナーゼ、イノシトールリン脂質3キナーゼ、PI3-キナーゼ、PI3キナーゼ

関

1-phosphatidylinositol 3-kinase、phosphatidylinositol 3-kinase、phosphoinositide 3-kinase、PI 3-kinase、PI-3 kinase、PI-3K、PI3K、PtdIns 3-kinase

「PI 3-kinase」

　　[★]

ホスファチジルイノシトール3キナーゼ、ホスホイノシチド3キナーゼ、イノシトールリン脂質3キナーゼ、PI-3キナーゼ

関

1-phosphatidylinositol 3-kinase、phosphatidylinositol 3-kinase、phosphoinositide 3-kinase、PI-3 kinase、PI-3K、PI3-kinase、PI3K、PtdIns 3-kinase

「PI-3K」

　　[★]

• ホスファチジルイノシトール3キナーゼ、ホスホイノシチド3キナーゼ

関

1-phosphatidylinositol 3-kinase、phosphatidylinositol 3-kinase、phosphoinositide 3-kinase、PI 3-kinase、PI-3 kinase、PI3-kinase、PI3K、PtdIns 3-kinase

「ホスファチジルイノシトール-3-キナーゼ」

　　[★]

英

phosphatidylinositol 3-kinase、PtdIns 3-kinase

関

ホスファチジルイノシトール3キナーゼ、ホスホイノシチド3キナーゼ、イノシトールリン脂質3キナーゼ、1-ホスファチジルイノシトール-3-キナーゼ

「1-phosphatidylinositol 3-kinase」

　　[★]

1-ホスファチジルイノシトール-3-キナーゼ

関

phosphatidylinositol 3-kinase、PI 3-kinase、PI-3 kinase、PI-3K、PI3-kinase、PtdIns 3-kinase

「PtdIns」

　　[★]

ホスファチジルイノシトール

• ホスファチジルイノシトール

関

inositol phospholipid、phosphatidyl inositol、phosphatidylinositol、phosphoinositide、PI

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase