WordNet

used to signify the Union forces in the American Civil War (who wore blue uniforms); "a ragged blue line"
blue color or pigment; resembling the color of the clear sky in the daytime; "he had eyes of bright blue" (同)blueness
any of numerous small butterflies of the family Lycaenidae
blue clothing; "she was wearing blue"
any organization or party whose uniforms or badges are blue; "the Union army was a vast blue"
of the color intermediate between green and violet; having a color similar to that of a clear unclouded sky; "Octobers bright blue weather"- Helen Hunt Jackson; "a blue flame"; "blue haze of tobacco smoke" (同)bluish, blueish
causing dejection; "a blue day"; "the dark days of the war"; "a week of rainy depressing weather"; "a disconsolate winter landscape"; "the first dismal dispiriting days of November"; "a dark gloomy day"; "grim rainy weather" (同)dark, dingy, disconsolate, dismal, gloomy, grim, sorry, drab, drear, dreary
suggestive of sexual impropriety; "a blue movie"; "blue jokes"; "he skips asterisks and gives you the gamy details"; "a juicy scandal"; "a naughty wink"; "naughty words"; "racy anecdotes"; "a risque story"; "spicy gossip" (同)gamy, gamey, juicy, naughty, racy, risque, spicy
morally rigorous and strict; "the puritan work ethic"; "puritanic distaste for alcohol"; "she was anything but puritanical in her behavior" (同)puritanic, puritanical
turn blue
(microscopy) a dye or other coloring material that is used in microscopy to make structures visible
color for microscopic study; "The laboratory worker dyed the specimen"
color with a liquid dye or tint; "Stain this table a beautiful walnut color"; "people knew how to stain glass a beautiful blue in the middle ages"
produce or leave stains; "Red wine stains the table cloth"
a soiled or discolored appearance; "the wine left a dark stain" (同)discoloration, discolouration
a former kingdom in north-central Europe including present-day northern Germany and northern Poland; "in the 19th century Prussia led the economic and political unification of the German states" (同)Preussen
of or relating to or characteristic of Prussia or its inhabitants; "Prussian officers"; "Prussian aristocracy"
a German inhabitant of Prussia
a state of depression; "he had a bad case of the blues" (同)blue devils, megrims, vapors, vapours
a type of folksong that originated among Black Americans at the beginning of the 20th century; has a melancholy sound from repeated use of blue notes

PrepTutorEJDIC

『青い』,あい色の / 青黒い / 《話》陰気な,憂うつな / 〈U〉『青色』,あい色;青色の着物 / 〈U〉〈C〉青色絵の具,あい色染料 / 《the~》《詩》青空,青い海 / 《the blues》《話》気のふさぎ,うれいの色 / 《the blues》《ときに単数扱い》(ジャズ音楽の)ブルース / …'を'青色にする
(…で)…‘を'『汚す』,‘に'しみをつける《+『名』+『with』+『名』》 / 〈ガラス・木材・布など〉‘に'『着色する』 / (…で)〈人格・名声など〉‘を'汚す,‘に'傷をつける《+『名』+『with』+『名』》 / 汚れる,しみがつく / 〈C〉〈U〉(…についた)『しみ』,汚れ《+『on』+『名』》 / 〈U〉〈C〉着色剤,染料 / 〈C〉(人格・名声などに対する)汚点,傷《+『on』(『upon』)+『名』》
プロシア(1871年までドイツ北東部にあった王国;ドイツ語ではプロイセン)
プロシアの;プロシア人(語)の / 〈C〉プロシア人;〈U〉プロシア語

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/15 21:10:32」(JST)

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Prussian blue is a common stain used by pathologists to detect the presence of iron in biopsy specimens, such as deposits of storage ferritin in bone marrow biopsy samples.

The original stain formula, known historically (1867) as "Perls' Prussian blue" after its inventor, German pathologist Max Perls (1843-1881), used separate solutions of potassium ferrocyanide and acid to stain tissue (these are now used combined, just before staining). Ferric iron deposits in tissue (present mostly as ferric iron within the storage protein ferritin) then react with the soluble ferrocyanide in the stain, to form insoluble Prussian blue dye (a complex hydrated ferric ferrocyanide substance) in situ (i.e., in place). They are then visualizable microscopically as blue or purple deposits, within cells.^[1] The formula is also known as Perls Prussian blue and (incorrectly) as Perl's Prussian blue.

References

^ http://www.scribd.com/doc/4448747/Perl Formula for Perls' Prussian blue stain. Accessed April 2, 2009.

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2. 遺伝性のびまん性胃癌 hereditary diffuse gastric cancer
3. 炎症性腸疾患における大腸癌のサーべイランス colorectal cancer surveillance in inflammatory bowel disease
4. Barrett's esophagus: Evaluation with narrow band imaging
5. 拡大内視鏡検査 magnification endoscopy

English Journal

Diffuse parenchymal form of malakoplakia in renal transplant recipient: a case report.

Keitel E, Pêgas KL, do Nascimento Bittar AE, Dos Santos AF, da Cas Porto F, Cambruzzi E.AbstractMalakoplakia is an unusual chronic inflammatory disease related to prior urinary tract infection. It is characterized by the presence of macrophages with foamy cytoplasm exhibiting larger PAS positive inclusions that stain for calcium and iron. Malakoplakia affects renal allograft and is associated with severe morbidity. Herein, the authors report a new case of renal graft malakoplakia in a 23-year-old female patient. The patient received a living-related donor renal transplantation with a high immunological risk. Plasmapheresis and intravenous immunoglobulin (i.v. Ig) treatment, pre- and post-transplant, and induction with rabbit anti-thymocyte globulins were used due to presence of donor specific antibodies and positive B cross match by flow cytometry. The patient had an early urinary tract infection with a good outcome. On Day 36 post-transplant (PO), the patient returned to the clinic with fever, graft pain and acute renal dysfunction leading to hemodialysis. Escherichia coli (E. coli) was present in the blood and urine culture. At the time, the renal biopsy revealed numerous sheets of macrophages with foamy, eosinophilic cytoplasm showing several PAS positive granules and large inclusions that stained strongly with hematoxylin, calcium (von Kossa method) and iron (Prussian blue). The patient was diagnosed with malakoplakia related to a kidney transplant. Despite prolonged treatment with antibiotics, determined by a susceptibility test, the patient did not recover renal function and remained on dialysis.
Clinical nephrology.Clin Nephrol.2012 Nov 29. [Epub ahead of print]
Malakoplakia is an unusual chronic inflammatory disease related to prior urinary tract infection. It is characterized by the presence of macrophages with foamy cytoplasm exhibiting larger PAS positive inclusions that stain for calcium and iron. Malakoplakia affects renal allograft and is associated
PMID 23195831

Mechanism of protective effects of Danshen against iron overload-induced injury in mice.

Gao Y, Wang N, Zhang Y, Ma Z, Guan P, Ma J, Zhang Y, Zhang X, Wang J, Zhang J, Chu L.SourceDepartment of Pharmacology, School of Basic Medicine, Hebei Medical University, 326, Xinshi South Road, Shijiazhuang, 050091 Hebei, China.
Journal of ethnopharmacology.J Ethnopharmacol.2012 Nov 10. pii: S0378-8741(12)00758-1. doi: 10.1016/j.jep.2012.10.060. [Epub ahead of print]
ETHNOPHARMACOLOGICAL RELEVANCE: Danshen (Salvia miltiorrhiza) has been widely prescribed in traditional folk medicine for treatment of hepatic and cardiovascular diseases in China and other Asian countries for several hundred years.MATERIALS AND METHODS: Sixty male mice were randomly divided into fi
PMID 23147497

Japanese Journal

分化部分にヘモジデリン沈着がみられた甲状腺未分化癌の1例

舟橋正範,金子千之,加藤一夫,野村七夫,江崎正則
日本臨床細胞学会雑誌 37(4), 440-441, 1998-07-22
NAID 110001225157

Bromchlorphenol Blueを用いた血液標本の迅速鉄染色法の検討

高宮脩,松本登貴夫,田中恒二
紀要 20, 1-4, 1994
… For iron-staining on bone marrow and blood smears, Prussian blue reaction has been conventional. … had developed the cytochemical iron-staining using bromchorphenol blue (dibrom-dichlorphenol sulfonphthalein). … The positive ratio and scoring for this iron-staining on bone marrow and blood smears from patients with various blood diseases correlated well with those for the traditional method by prussian blue reaction. …
NAID 110000547207