ピブメシリナム, pivmecillinam
English Journal
- Barnacle Cement as Surface Anchor for 'Clicking' of Antifouling and Antimicrobial Polymer Brushes on Stainless Steel.
- Yang WJ, Cai T, Neoh KG, Kang ET, Teo SL, Rittschof D.AbstractBarnacle cement (BC) was utilized 'beneficially' as a surface anchor on stainless steel (SS) for coupling of functional polymer brushes via 'click' reactions in both "grafting-to" and "grafting-from" processes. Ethylene sulfide (ES), propargyl carbonylimidazole (PPC) and azidoethyl carbonylimidazole (AEC) reacted with amine and/or hydroxyl groups in BC to introduce the corresponding thiol, alkyne and azide groups on SS surfaces (SS-thiol, SS-alkyne and SS-azide, respectively). Antifouling zwitterionic SS-PMPC surface was prepared by thiol-ene photopolymerization of 2-methacryloyloxyethyl phosphorylcholine (MPC) from the SS-thiol surface. Protein-resistant SS-PPEGMA and protein-adsorbing SS-PPFS surfaces were prepared by coupling of the respective azide-functionalized poly(poly(ethylene glycol)methyl ether methacrylate) (azido-PPEGMA) and poly(2,3,4,5,6-pentafluorostyrene) (azido-PPFS) polymer brushes in azide-alkyne 'click' reaction. Antifouling alkyne-functionalized poly(N-hydroxyethyl acrylamide) (alkynyl-PHEAA) and antibacterial alkyne-functionalized poly(2-(methacryloyloxy)ethyl trimethylammonium chloride) (alkynyl-PMETA) polymer brushes were clicked on the SS-azide surface. Adsorption of bovine serum albumin and bacteria fouling of Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus epidermidis (S. epidermidis) were investigated on the polymer-functionalized SS surfaces. The versatile bio-anchor and functional polymer brush coatings are stable in abiotic aqueous environment for over a month.
- Biomacromolecules.Biomacromolecules.2013 May 3. [Epub ahead of print]
- Barnacle cement (BC) was utilized 'beneficially' as a surface anchor on stainless steel (SS) for coupling of functional polymer brushes via 'click' reactions in both "grafting-to" and "grafting-from" processes. Ethylene sulfide (ES), propargyl carbonylimidazole (PPC) and azidoethyl carbonylimidazole
- PMID 23641901
- Induction of apoptosis in non-small cell lung cancer by downregulation of MDM2 using pH-responsive PMPC-b-PDPA/siRNA complex nanoparticles.
- Yu H, Zou Y, Jiang L, Yin Q, He X, Chen L, Zhang Z, Gu W, Li Y.SourceCenter of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
- Biomaterials.Biomaterials.2013 Apr;34(11):2738-47. doi: 10.1016/j.biomaterials.2012.12.042. Epub 2013 Jan 24.
- Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer caused human death. In this work, we selected oncogene mouse double minute 2 (MDM2) as a therapeutic target for NSCLC treatment and proposed that sufficient MDM2 knockdown could inhibit tumor growth via induction of cell cyc
- PMID 23352573
- Enhanced drug delivery to melanoma cells using PMPC-PDPA polymersomes.
- Pegoraro C, Cecchin D, Gracia LS, Warren N, Madsen J, Armes SP, Lewis A, Macneil S, Battaglia G.SourceThe Krebs Institute, University of Sheffield, Sheffield, UK; The Centre of Membrane Interaction and Dynamics, University of Sheffield, Sheffield, UK; The CRUK/YCR Sheffield Cancer Research Centre, University of Sheffield, Sheffield, UK; Department of Biomedical Sciences, University of Sheffield, Sheffield, UK; Department of Materials Science and Engineering, University of Sheffield, Sheffield, UK; Kroto Research Institute, University of Sheffield, Sheffield, UK.
- Cancer letters.Cancer Lett.2013 Feb 10. pii: S0304-3835(13)00118-3. doi: 10.1016/j.canlet.2013.02.007. [Epub ahead of print]
- We present the efficient and stable encapsulation of doxorubicin within pH sensitive polymeric vesicles (polymersomes) for intracellular and nuclear delivery to melanoma cells. We demonstrate that PMPC25-PDPA70 polymersomes can encapsulate doxorubicin for long periods of time without significant dru
- PMID 23402813
Japanese Journal
- 有機テルル化合物を用いたラジカル重合(TERP)による生体適合性ホスホリルコリン基を含むブロックコポリマーの合成 (特集号 精密高分子合成の展望(1))
- 高分子論文集 = Japanese journal of polymer science and technology 72(5), 335-340, 2015
- NAID 40020487441
- 有機テルル化合物を用いたラジカル重合(TERP)による生体適合性ホスホリルコリン基を含むブロックコポリマーの合成
- 有機テルル化合物を用いたラジカル重合(TERP)による生体適合性ホスホリルコリン基を含むブロックコポリマーの合成
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- PMPC Civil Engineers is an Engineering firm based out of Saratoga Wyoming. They specialize in project planning for civil engineering projects
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