WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

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PACAP system evolution and its role in melanophore function in teleost fish skin.

Cardoso JC1, Félix RC2, Martins RS2, Trindade M2, Fonseca VG2, Fuentes J2, Power DM2.
Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Aug 15;411:130-45. doi: 10.1016/j.mce.2015.04.020. Epub 2015 Apr 28.
Pituitary adenylate cyclase-activating polypeptide (PACAP) administered to tilapia melanophores ex-vivo causes significant pigment aggregation and this is a newly identified function for this peptide in fish. The G-protein coupled receptors (GPCRs), adcyap1r1a (encoding Pac1a) and vipr2a (encoding V
PMID 25933704

Meier JJ1, Nauck MA.
Diabetologia.Diabetologia.2015 Aug;58(8):1745-50. doi: 10.1007/s00125-015-3608-6. Epub 2015 May 21.
The development of incretin-based therapies (glucagon-like peptide 1 [GLP-1] receptor agonists and dipeptidyl peptidase-4 [DPP-4] inhibitors) has changed the landscape of type 2 diabetes management over the past decade. Current developments include longer-acting GLP-1 receptor agonists, fixed-ratio
PMID 25994073

Functional Pairing of Class B1 Ligand-GPCR in Cephalochordate Provides Evidence of the Origin of PTH and PACAP/Glucagon Receptor Family.

On JS1, Duan C2, Chow BK1, Lee LT3.
Molecular biology and evolution.Mol Biol Evol.2015 Aug;32(8):2048-59. doi: 10.1093/molbev/msv087. Epub 2015 Apr 3.
Several hypotheses have been proposed regarding the origin and evolution of the secretin family of peptides and receptors. However, identification of homologous ligand-receptor pairs in invertebrates and vertebrates is difficult because of the low levels of sequence identity between orthologs of dis
PMID 25841489

Diazepam Enhances Production of Diazepam-Binding Inhibitor (DBI), a Negative Saliva Secretion Regulator, Localized in Rat Salivary Gland

Tsukagoshi Eri,Kawaguchi Mitsuru,Shinomiya Takashi [他],YOSHIKAWA Masanobu,KAWANO Toshihiko,OKUBO Migiwa,SAWAKI Kohei
Journal of pharmacological sciences 115(2), 221-229, 2011-02-20
… Peripheral-type benzodiazepine receptor (PBR) and central-type benzodiazepine receptor (CBR) in salivary gland play a role in the inhibitory regulation of salivary secretion in rodents. … Moreover, mRNA expression of PBR and pituitary adenylate cyclase–activating polypeptide (PACAP), a transcriptional regulator for DBI promoter, was evaluated after repetitive administration of DZP. …
NAID 10029892190

IS-81 Stimulatory Effect of Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP) and its PACAP Type I Receptor (PAC1R) on Prolactin Synthesis in Rat Pituitary Somatolactotrophs(Group10 Reproduction4,International Session)

Tselmeg Mijiddorj,Kanasaki Haruhiko,Indri Purwana,Oride Aki,Ishikawa Masako,Imamura Kayo,Katagiri Atsuko,Yamagami Ikuko,Nakayama Kentaro,Aoki Showa,Miyazaki Kohji
日本産科婦人科學會雜誌 63(2), 940, 2011-02-01
NAID 110008510234

(2)中枢神経系に存在する生理活性物質Pituitary Adenylate Cyclase-Activating Polypeptide(PACAP)によるゴナドトロピン産生調節(<特集>第61回学術講演会シンポジウム2「中枢神経関連生理活性物質の生殖機能へのかかわり」)

金崎春彦
日本産科婦人科學會雜誌 61(10), 1915-1924, 2009-10-01
… We examined how pulsatile stimulation with Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) affected gonadotrophs. … In contrast, PACAP increased α-subunit promoter activity, but failed to increase LHβ and FSHβ promoters. … Messenger RNAs for LHβ and FSHβ were slightly but significantly increased by PACAP stimulation. …
NAID 110007387117

リンク元	「脳下垂体アデニル酸シクラーゼ活性化ポリペプチド受容体」「脳下垂体アデニル酸シクラーゼ活性化ポリペプチドレセプター」「PACAPレセプター」「pituitary adenylate cyclase-activating polypeptide receptor」
拡張検索	「type I PACAP receptor」
関連記事	「PACAP」「PAC」