Na+-glucose cotransporter

• Na+/グルコース共輸送体

関

sodium-glucose cotransporter、sodium-glucose transport protein

WordNet

1. the 14th letter of the Roman alphabet (同)n
2. a monosaccharide sugar that has several forms; an important source of physiological energy

PrepTutorEJDIC

1. nitrogenの化学記号
2. ブドウ糖
3. sodium(ラテン語natrium)の化学記号

UpToDate Contents

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• 1. Chapter 3B：近位尿細管におけるナトリウム輸送能の優越性 chapter 3b primacy of sodium transport in proximal function
• 2. Chapter 3A：近位尿細管輸送の細胞モデル chapter 3a cell model for proximal transport
• 3. 赤血球水分量の制御 control of red blood cell hydration
• 4. バーター症候群およびギテルマン症候群 bartter and gitelman syndromes
• 5. Chapter 4A：ヘンレループにおける輸送の細胞モデル chapter 4a cell model for loop of henle transport

English Journal

• Cooperative anti-diabetic effects of deoxynojirimycin-polysaccharide by inhibiting glucose absorption and modulating glucose metabolism in streptozotocin-induced diabetic mice.

• Li YG, Ji DF, Zhong S, Lv ZQ, Lin TB.SourceSericultural Research Institute, Zhejiang Academy of Agricultural Science, Hangzhou, China.
• PloS one.PLoS One.2013 Jun 6;8(6):e65892. doi: 10.1371/journal.pone.0065892. Print 2013.
• We had previously shown that deoxynojirimycin-polysaccharide mixture (DPM) not only decreased blood glucose but also reversed the damage to pancreatic β-cells in diabetic mice, and that the anti-hyperglycemic efficacy of this combination was better than that of 1-deoxynojirimycin (DNJ) or polysachh
• PMID 23755289

• Congenital glucose-galactose malabsorption: a novel deletion within the SLC5A1 gene.

• Vallaeys L, Van Biervliet S, De Bruyn G, Loeys B, Moring AS, Van Deynse E, Cornette L.SourceDepartment of Neonatology, AZ Sint-Jan Brugge-Oostende AV, Ruddershove 10, 8000, Bruges, Belgium.
• European journal of pediatrics.Eur J Pediatr.2013 Mar;172(3):409-11. doi: 10.1007/s00431-012-1802-9. Epub 2012 Jul 29.
• Glucose-galactose malabsorption (GGM) is an autosomal recessive disease caused by mutations in the Na(+)/glucose cotransporter gene SLC5A1 (OMIM 182380, phenotype number 606824). Patients with GGM present with neonatal onset of severe life-threatening diarrhoea and dehydration. We describe a 5-day-o
• PMID 22843301

• Regional distribution of SGLT activity in rat brain in vivo.

• Yu AS, Hirayama BA, Timbol G, Liu J, Diez-Sampedro A, Kepe V, Satyamurthy N, Huang SC, Wright EM, Barrio JR.SourceDepartment of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
• American journal of physiology. Cell physiology.Am J Physiol Cell Physiol.2013 Feb 1;304(3):C240-7. doi: 10.1152/ajpcell.00317.2012. Epub 2012 Nov 14.
• Na(+)-glucose cotransporter (SGLT) mRNAs have been detected in many organs of the body, but, apart from kidney and intestine, transporter expression, localization, and functional activity, as well as physiological significance, remain elusive. Using a SGLT-specific molecular imaging probe, α-methyl
• PMID 23151803

Japanese Journal

• 下痢,嘔吐 (特集 小児の輸液ベーシックガイド)

• 上原 朋子,松山 健
• 小児科診療 74(2), 219-225,308, 2011-02
• NAID 40018277207

• 腎ナトリウム共輸送体及び交換体並びに関連輸送タンパク質の発現と調節因子

• 祐田 泰延
• 藥學雜誌 128(6), 901-917, 2008-06-01
• … Thus, sodium-dependent glucose transport has been studied on sodium-dependent glucose transporters such as SGLT1 and SGLT2 using cell lines of porcelain renal cell, LLC-PK_1, and murine renal cell, NRK-52E. …
• NAID 110006687003

• Mechanism of Cd-Induced Inhibition of Na-Glucose Cotransporter in Rabbit Proximal Tubule Cells: Roles of Luminal pH and Membrane-Bound Carbonic Anhydrase

• Tsuruoka Shuichi,Swenson Erik R.,Fujimura Akio,Imai Masashi
• Nepron Physiology 110(2), 11-20, 2008
• … Background/Aims: We have previously reported that a complex of cadmium-metallothionein (Cd-MT) directly affects the apical Na-glucose cotransporter on the luminal side in proximal tubules, suggesting that Cd-MT is more toxic than CdCl2 in causing tubulopathy. …
• NAID 120000994527

Related Links

• Sodium-glucose transport proteins - Wikipedia, the free encyclopedia

In August 1960, in Prague, Robert K. Crane presented for the first time his discovery of the sodium-glucose cotransport as the mechanism for intestinal glucose absorption.

• Regulation of Na+/glucose cotransporters.

Na+/glucose cotransporters (SGLTs) are expressed in the small intestine and the proximal renal tubule, where they play a central role in the absorption of glucose and galactose from food and the reabsorption of glucose from the glomerular ...

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★リンクテーブル★

関連記事	「NA」「cotransport」「cotransporter」「N」「nA」

「NA」

　　[★]

• ノルアドレナリン, noradrenaline
• ノイラミニダーゼ, neur-aminidase
• Narcotics Anonymous
• ナリジクス酸 nalidixic acid

「cotransport」

　　[★]

• 共輸送、等方輸送、共輸送する

関

co-transport、symport

「cotransporter」

　　[★]

• 共輸送体、コトランスポーター

関

co-transporter、symporter

「N」

　　[★]

• アスパラギン asparagine
• 窒素(原子、分子)

　 　

「nA」

　　[★] ナノアンペア nanoampere