ヘテロ接合性欠失 loss of heterozygosity
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- the 12th letter of the Roman alphabet (同)l
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- lira(イタリアの貨幣単位リラ)
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/30 09:55:09」(JST)
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- 1. ゲノム疾患：概要 genomic disorders an overview
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English Journal
- Estimating cumulative live-birth rates after IVF treatment with Kaplan-Meier and competing risk methods.
- Viardot-Foucault V1, Tai BC2, Chen ZJ3, Lim GH4, Loh SF5, Tan HH6, Nadarajah S6, Chan JK7.
- European journal of obstetrics, gynecology, and reproductive biology.Eur J Obstet Gynecol Reprod Biol.2015 Sep;192:41-6. doi: 10.1016/j.ejogrb.2015.06.015. Epub 2015 Jun 25.
- OBJECTIVE(S): To explore the use of competing risk (CR) as compared to the commonly used Kaplan-Meier (KM) methodology in estimating the cumulative live-birth rate (CLBR) after IVF Treatment in a context of high dropout rates and informative censoring.STUDY DESIGN: We compare the KM and CR methodolo
- PMID 26149478
- Somatic alterations in juvenile polyps from BMPR1A and SMAD4 mutation carriers.
- Blatter RH1, Plasilova M1,2, Wenzel F3, Gokaslan ST4, Terracciano L5, Ashfaq R6, Heinimann K1,3.
- Genes, chromosomes & cancer.Genes Chromosomes Cancer.2015 Sep;54(9):575-82. doi: 10.1002/gcc.22270. Epub 2015 Jul 14.
- Juvenile polyposis syndrome (JPS) is a rare autosomal dominant disorder predisposing to gastrointestinal hamartomatous polyps and cancer with a pathogenic SMAD4 or BMPR1A germline mutation (1st-hit) being identified in about 40-50% of patients. Little is known, however, about the occurrence and natu
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- Effects of Indomethacin on Intracellular pH and Na⁺/H⁺ Exchanger in the Human Monocytes.
- Tsai YT1,2, Lee CY1, Chuang CC3, Lin HJ4, Wu CH3, Yang YZ3, Tsai CS1,2,3, Loh SH2,3.
- The Chinese journal of physiology.Chin J Physiol.2015 Aug 31;58(4). pii: CJP.2015.BAD310. doi: 10.4077/CJP.2015.BAD310. [Epub ahead of print]
- The ability to maintain optimal intracellular pH (pHi) is an essential requirement for all cells. Na⁺-H⁺ exchanger (NHE), a ubiquitously expressed transmembrane protein, has been found widely as a major acid extruder in many different cell types, including human monocytes. We therefore investiga
- PMID 26211646
Japanese Journal
- <BOOK REVIEWS> Reading Bangkok. ROSS KING. Singapore: NUS Press, 2011, 272 p.
- Loh Kah Seng
- Southeast Asian Studies 1(2), 339-341, 2012-08-31
- NAID 110009443407
- セミナー テストステロンを再考する(3)LOHとテストステロン
- 杉本 和宏,重原 一慶,小中 弘之 [他]
- 臨床泌尿器科 66(9), 665-669, 2012-08
- NAID 40019396955
Related Links
- LOH症候群【加齢男性性腺機能低下症候群】について、症状や診断基準などLOH症候群と判断する過程で重要なポイントを紹介します。また、LOH症候群の治療に伴う副作用やリスクについても言及し、対策をどのようにしているかなど ...
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★リンクテーブル★
| リンク元 | 「ヘテロ接合性欠失」「局所性骨溶解性高カルシウム血症」「loss of heterozygosity」 |
| 拡張検索 | 「LOH症候群」 |
| 関連記事 | 「L」 |
「ヘテロ接合性欠失」
参考1
- Loss of heterozygosity (LOH) in a cell represents the loss of normal function of one allele of a gene in which the other allele was already inactivated. This term is mostly used in the context of oncogenesis; after an inactivating mutation in one allele of a tumor suppressor gene occurs in the parent's germline cell, it is passed on to the zygote resulting in an offspring that is heterozygous for that allele. In oncology, loss of heterozygosity occurs when the remaining functional allele in a somatic cell of the offspring becomes inactivated by mutation. This results in no normal tumor suppressor being produced and this could result in tumorigenesis.
参考
- 1. wikipedia en
「局所性骨溶解性高カルシウム血症」
「loss of heterozygosity」
「LOH症候群」
「L」