WordNet

direct the flow of; "channel information towards a broad audience" (同)canalize, canalise
a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels" (同)television channel, TV channel
a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"
(often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms" (同)communication channel, line
a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company" (同)transmission channel
a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"
a light soft silver-white metallic element of the alkali metal group; oxidizes rapidly in air and reacts violently with water; is abundant in nature in combined forms occurring in sea water and in carnallite and kainite and sylvite (同)K, atomic number 19
official routes of communication; "you have to go through channels"

PrepTutorEJDIC

〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す
ポタシウム,カリウム(金属元素;化学記号はK)

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1. 心筋活動電位および抗不整脈剤の作用 myocardial action potential and action of antiarrhythmic drugs
2. 赤血球水分量の制御 control of red blood cell hydration
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4. 肺高血圧症の病因 pathogenesis of pulmonary hypertension
5. 幼児の持続性高インスリン血症性低血糖症の病因、臨床的特徴、および診断 pathogenesis clinical features and diagnosis of persistent hyperinsulinemic hypoglycemia of infancy

Chege SW, Hortopan GA, T Dinday M, Baraban SC.SourcePIBS Graduate Program in Neuroscience, University of California, San Francisco, San Francisco, California 94143, USA.
Developmental neurobiology.Dev Neurobiol.2012 Feb;72(2):186-98. doi: 10.1002/dneu.20937.
Members of the K(v)7 family generate a subthreshold potassium current, termed M-current, that regulates the excitability of principal central neurons. Mutations in two members of this family, K(v)7.2 (KCNQ2) and K(v)7.3 (KCNQ3) are associated with a neurological disorder known as benign familial neo
PMID 21692188

Retigabine, a K(V)7 (KCNQ) potassium channel opener, attenuates L-DOPA-induced dyskinesias in 6-OHDA-lesioned rats.

Sander SE, Lemm C, Lange N, Hamann M, Richter A.SourceInstitute of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Freie Universität Berlin, Koserstr. 20, 14195 Berlin, Germany. sander.svenja@vetmed.fu-berlin.de
Neuropharmacology.Neuropharmacology.2012 Feb;62(2):1052-61. Epub 2011 Nov 9.
L-DOPA-induced dyskinesias (LID) represent a severe complication of long-time pharmacotherapy in Parkinson's disease that necessitates novel therapeutics. The acute and chronic effects of K(V)7.2-7.5 channel openers (retigabine, flupirtine) on the severity of LID and parkinsonian signs were examined
PMID 22079161

Ishii Kuniaki,Norota Ikuo,Obara Yutaro
Journal of Pharmacological Sciences 120(4), 264-269, 2012
… Functional changes have been extensively investigated for many ion channels including cardiac voltage-dependent potassium channels. … By contrast, the regulation of ion channel numbers has not been widely examined, particularly with respect to acute modulation of ion channels. … This article briefly summarizes stimulus-induced endocytic regulation of major voltage-dependent potassium channels in the heart. …
NAID 130002505880

Swelling-activated potassium channel in porcine pigmented ciliary epithelial cells.

Takahira Masayuki,Sakurai Mayumi,Sakurada Norimasa,Sugiyama Kazuhisa
Investigative ophthalmology & visual science 52(8), 5928-5932, 2011-07-00
… Linopirdine, a specific inhibitor of KCNQ channels, effectively blocked the K(+) current in these PCE cells. … Porcine PCE cells express a swelling-activated K(+) channel, which may be a member of the KCNQ/Kv7 channel family. … This K(+) channel is active near resting potentials and could contribute to the regulation of cell volume and water transport via the ciliary epithelia. …
NAID 120003479729

S Kass Robert
Journal of Arrhythmia 27(Supplement), SS1_1, 2011
… Channelopathies are diseases caused by inherited mutations in genes coding for ion channels or channel associated proteins. … ion channel structure and function; … and particularly the manner in which potassium channels; … and channel-associated proteins regulate the plateau phase of the cardiac action potential. …
NAID 130002130104