WordNet

direct the flow of; "channel information towards a broad audience" (同)canalize, canalise
a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels" (同)television channel, TV channel
a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"
(often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms" (同)communication channel, line
a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company" (同)transmission channel
a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"
a light soft silver-white metallic element of the alkali metal group; oxidizes rapidly in air and reacts violently with water; is abundant in nature in combined forms occurring in sea water and in carnallite and kainite and sylvite (同)K, atomic number 19
official routes of communication; "you have to go through channels"

PrepTutorEJDIC

〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す
ポタシウム,カリウム(金属元素;化学記号はK)

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1. 先天性および後天性ＱＴ延長症候群の遺伝学 genetics of congenital and acquired long qt syndrome
2. 心筋活動電位および抗不整脈剤の作用 myocardial action potential and action of antiarrhythmic drugs
3. 赤血球水分量の制御 control of red blood cell hydration
4. 2型糖尿病の病因 pathogenesis of type 2 diabetes mellitus
5. ガストリンの生理学 physiology of gastrin

Enhanced Effects of Isoflurane on the Long QT Syndrome 1-associated A341V Mutant.

Mikuni I1, Torres CG, Bakshi T, Tampo A, Carlson BE, Bienengraeber MW, Kwok WM.
Anesthesiology.Anesthesiology.2015 Apr;122(4):806-20. doi: 10.1097/ALN.0000000000000583.
BACKGROUND: The impact of volatile anesthetics on patients with inherited long QT syndrome (LQTS) is not well understood. This is further complicated by the different genotypes underlying LQTS. No studies have reported on the direct effects of volatile anesthetics on specific LQTS-associated mutatio
PMID 25585005

Kv7 channels critically determine coronary artery reactivity: left-right differences and down-regulation by hyperglycaemia.

Morales-Cano D1, Moreno L1, Barreira B1, Pandolfi R1, Chamorro V1, Jimenez R2, Villamor E3, Duarte J2, Perez-Vizcaino F1, Cogolludo A4.
Cardiovascular research.Cardiovasc Res.2015 Apr 1;106(1):98-108. doi: 10.1093/cvr/cvv020. Epub 2015 Jan 23.
AIMS: Voltage-gated potassium channels encoded by KCNQ genes (Kv7 channels) are emerging as important regulators of vascular tone. In this study, we analysed the contribution of Kv7 channels to the vasodilation induced by hypoxia and the cyclic AMP pathway in the coronary circulation. We also assess
PMID 25616413

Steffensen AB1, Refsgaard L, Andersen MN, Vallet C, Mujezinovic A, Haunsø S, Svendsen JH, Olesen SP, Olesen MS, Schmitt N.
Journal of cardiovascular electrophysiology.J Cardiovasc Electrophysiol.2015 Mar 19. doi: 10.1111/jce.12666. [Epub ahead of print]
INTRODUCTION: Atrial fibrillation (AF) is the most frequent cardiac arrhythmia. The potassium current IKs is essential for cardiac repolarization. Gain-of-function mutation in KCNQ1, the gene encoding the pore-forming α-subunit of the IKs channel (KV 7.1), was the first ion channel dysfunction to b
PMID 25786344

Blocking Effect of NIP-142 on the KCNQ1/KCNE1 Channel Current Expressed in HEK293 Cells

Namekata Iyuki,Tsuruoka Noriko,Tsuneoka Yayoi,Matsuda Tomoyuki,Takahara Akira,Tanaka Yoshio,Suzuki Takeshi,Takahashi Tetsuo,Iida-Tanaka Naoko,Tanaka Hikaru
Biological & Pharmaceutical Bulletin 34(1), 153-155, 2011
… We examined the effect of NIP-142, a benzopyran compound with terminating effect on experimental atrial arrhythmia, on the KCNQ1/KCNE1 channel, which underlies the slow component of the cardiac delayed rectifier potassium channel (IKs). … These results indicate that NIP-142 has blocking effect on the KCNQ1/KCNE1 channel current. …
NAID 130000402280