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English Journal

The role of insulin-like-growth factor binding protein 2 (IGFBP2) and phosphatase and tensin homologue (PTEN) in the regulation of myoblast differentiation and hypertrophy.

Sharples AP, Al-Shanti N, Hughes DC, Lewis MP, Stewart CE.SourceStem Cell, Ageing and Molecular Physiology (SCAMP) Unit, Research Institute for Sport and Exercise Sciences (RISES), School of Sport and Exercise Sciences, Liverpool John Moores University, Tom Reilly Building, Byrom Street, Liverpool, UK; Muscle Cellular and Molecular Physiology Research Group (MCMPRG), Institute for Sport and Physical Activity Research (ISPAR Bedford), Department of Sport and Exercise Sciences, University of Bedfordshire, UK; Institute for Biomedical Research into Human Movement and Health (IRM), Manchester Metropolitan University, Faculty of Science and Engineering, John Dalton Building, Oxford Road, Manchester, UK. Electronic address: a.p.sharples@googlemail.com.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.Growth Horm IGF Res.2013 Jun;23(3):53-61. doi: 10.1016/j.ghir.2013.03.004. Epub 2013 Apr 11.
The complex actions of the insulin-like-growth factor binding proteins (IGFBPs) in skeletal muscle are becoming apparent, with IGFBP2 being implicated in skeletal muscle cell proliferation and differentiation (Ernst et al., 1992; Sharples et al., 2010). Furthermore, PTEN signalling has been linked t
PMID 23583027

Animal Protein Intakes during Early Life and Adolescence Differ in Their Relation to the Growth Hormone-Insulin-Like-Growth-Factor Axis in Young Adulthood.

Joslowski G, Remer T, Assmann KE, Krupp D, Cheng G, Garnett SP, Kroke A, Wudy SA, Günther AL, Buyken AE.SourceIEL-Nutritional Epidemiology, University of Bonn, DONALD Study at the Research Institute of Child Nutrition, Dortmund, Germany.
The Journal of nutrition.J Nutr.2013 May 22. [Epub ahead of print]
Recent studies provide evidence that insulin-like-growth-factor I (IGF-I) and its binding proteins (IGFBP) IGFBP-2 and IGFBP-3 are related to the risk of several common cancers. It remains to be clarified whether their concentrations can be programmed by protein intake from different sources during
PMID 23700336

Expression levels of mRNA for insulin-like growth factors 1 and 2, IGF receptors and IGF binding proteins in in vivo and in vitro grown bovine follicles.

Rebouças EL, Costa JJ, Passos MJ, Silva AW, Rossi RO, van den Hurk R, Silva JR.SourceBiotechnology Nucleus of Sobral - NUBIS, Federal University of Ceara, Sobral, CE, Brazil.
Zygote (Cambridge, England).Zygote.2013 May 9:1-12. [Epub ahead of print]
Summary This study investigated mRNA levels for insulin-like growth factors (IGFs) IGF1 (IGF-I) and IGF2 (IGF-II), IGF receptors (IGF1R and IGF2R), and binding proteins (IGFBP-1, IGFBP-2. IGFBP-3, IGFBP-4, IGFBP-5 and IGFBP-6) in bovine follicles of 0.2, 0.5 or 1.0 mm in diameter. mRNA expression le
PMID 23659735

Circulating salmon 41-kDa insulin-like growth factor binding protein (IGFBP) is not IGFBP-3 but an IGFBP-2 subtype

Shimizu Munetaka,Suzuki Seira,Horikoshi Moeri,Hara Akihiko,Dickhoff Walton W.
General and Comparative Endocrinology 171(3), 326-331, 2011-05-01
… In mammals, the largest reservoir of IGF in the circulation comes from a large (150kDa) ternary complex comprised of IGF bound to IGFBP-3, which is bound to an acid label subunit (ALS), and this variant of IGFBP is regulated by growth hormone (GH) and feed intake. … Although multiple variants of IGFBPs ranging from 20 to 50 kDa have been found in fishes, no ternary complex is present and it has been assumed that the majority of circulating IGF is bound to fish IGFBP-3. …
NAID 120002973854

リンク元	「insulin-like growth factor binding protein 2」「インスリン様増殖因子結合タンパク質2」「インスリン様成長因子結合タンパク質2」
関連記事	「IGFBP」「IGF」