FLAP inhibition

関

lipoxygenase activating protein inhibition

UpToDate Contents

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• 1. 心血管疾患の危険因子の概要 overview of possible risk factors for cardiovascular disease
• 2. 自家組織を用いる乳房再建術の選択肢 options for flap based breast reconstruction
• 3. 軟部組織再建術に用いるフラップの概要 overview of flaps for soft tissue reconstruction
• 4. 乳房再建術および豊胸術の合併症 complications of reconstructive and aesthetic breast surgery
• 5. 下肢切断の手技 techniques for lower extremity amputation

English Journal

• Role of platelet inhibition in microvascular surgery.

• Cho EH1, Ligh C1, Hodulik KL2, Hollenbeck ST1.
• Journal of reconstructive microsurgery.J Reconstr Microsurg.2014 Nov;30(9):589-98. doi: 10.1055/s-0034-1381955. Epub 2014 Aug 4.
• Thrombosis remains a significant complication of microvascular free tissue transfer. Recent discoveries in the field of vascular biology have led to a greater understanding of thrombogenesis and the pivotal role that platelets play in the formation of a clot. However, current antithrombotic strategi
• PMID 25089565

• Curcumin inhibits proliferation of breast cancer cells through Nrf2-mediated down-regulation of Fen1 expression.

• Chen B1, Zhang Y2, Wang Y1, Rao J1, Jiang X1, Xu Z3.
• The Journal of steroid biochemistry and molecular biology.J Steroid Biochem Mol Biol.2014 Sep;143:11-8. doi: 10.1016/j.jsbmb.2014.01.009. Epub 2014 Jan 30.
• Curcumin can inhibit cell proliferation of breast cancer, but the mechanism for this inhibition remains unclear. Over-expression of Flap endonuclease 1 (Fen1), a DNA repair-specific nuclease, is involved in the development of breast cancer. Nrf2 is a master regulator of cellular antioxidant defense
• PMID 24486718

• Inhibition of the Notch Pathway Promotes Flap Survival by Inducing Functional Neoangiogenesis.

• Abbas OL1, Borman H, Terzi YK, Terzi A, Bayraktar N, Ozkan B, Yazc AC.
• Annals of plastic surgery.Ann Plast Surg.2014 Aug 28. [Epub ahead of print]
• OBJECTIVE: The Notch pathway seems to function as an antiangiogenic factor, negatively regulating the sprouting effect of vascular endothelial growth factor (VEGF). This function is well defined in embryonic and tumor vasculature. However, little is known about its function in ischemia-induced angio
• PMID 25180956

Japanese Journal

• 長期臥床症例に対する輪状軟骨鉗除を併用する声門閉鎖術

• 喉頭 20(1), 5-12, 2008
• NAID 130004647256

• 口腔悪性腫瘍の即時再建術に腹直筋皮弁を施行した症例に対する硬膜外麻酔を用いての周術期疼痛管理

• 東北大学歯学雑誌 15(2), 128-131, 1996-12
• NAID 110000407794

• 2.口蓋裂手術と顎発育に関する諸問題

• 日本口蓋裂学会雑誌 17(1), 7-14, 1992
• NAID 130004586319

Related Links

• Allosteric Wip1 phosphatase inhibition through flap-subdomain ...

Allosteric small-molecule inhibitors of the p53-induced oncogenic phosphatase Wip1 bind at a ‘flap’ subdomain near the catalytic site. Inhibitor GSK2830371 inhibits the phosphatase and oncogenic activities in cell lines and a ...

• Pol d Flap inhibition SUPPLEMENTARY FIGURE+LEGEND ...

! 4! With a T 1 gap substrate and different lengths of the flap, stabilization of Pol δ DV on the substrate occurs at those flap lengths that also show inhibition of strand displacement Figure S4. Primer extension activity in Buffer TM ...

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★リンクテーブル★

関連記事	「inhibition」「FLAP」「FL」「flap」

「inhibition」

　　[★]

• n.

• 1.抑止、抑制、阻止、禁止
• 2.抑止(阻止)するもの
• 3.(心理学)(衝動などの)抑制
• 4.(化)(化学反応の)抑制
• 5.(生物)(酵素の働きなどの)抑制、阻害

　 　 　 　

「FLAP」

　　[★]

• 5-lipoxygenase activating protein, 5-LOX-activating protein, 5-LOXAP, LOX5AP

関

lipoxygenase activating protein

「FL」

　　[★]

• 偽腔 false lumen
• 大腿骨長 femur length
• 焦線 focal line

　

「flap」

　　[★]

皮弁、フラップ

関

surgical flap