Viscerofugal neurons recorded from guinea-pig colonic nerves after organ culture.
Hibberd TJ, Zagorodnyuk VP, Spencer NJ, Brookes SJ.SourceDiscipline of Human Physiology and Centre for Neuroscience, Flinders University, Adelaide, Australia.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.Neurogastroenterol Motil.2012 Jul 19. doi: 10.1111/j.1365-2982.2012.01979.x. [Epub ahead of print]
Background Enteric viscerofugal neurons provide cholinergic synaptic inputs to prevertebral sympathetic neurons, forming reflex circuits that control motility and secretion. Extracellular recordings of identified viscerofugal neurons have not been reported. Methods Preparations of guinea pig d
Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer's disease.
Rancillac A, Geoffroy H, Rossier J.SourceLaboratoire de Neurobiologie, CNRS UMR 7637, ESPCI ParisTech, 10 rue Vauquelin, 75005 Paris, France. armelle.rancillac@espci.fr.
Current Alzheimer research.Curr Alzheimer Res.2012 Jul 11. [Epub ahead of print]
The tight coupling between neuronal activity and the local increase of blood flow termed neurovascular coupling is essential for normal brain function. This mechanism of regulation is compromised in Alzheimer's Disease (AD). In order to determine whether a purely vascular dysfunction or a neuronal a
Inhibition by SEA0400, a Selective Inhibitor of Na+/Ca2+ Exchanger, of Na+-Dependent Ca2+ Uptake and Catecholamine Release in Bovine Adrenal Chromaffin Cells
Journal of Pharmacological Sciences 102(1), 88-95, 2006
… In intact cells, SEA0400 and KB-R7943 inhibited CA release induced by acetylcholine and DMPP. … values of SEA0400 were 5.1 and 4.5 μM and the values of KB-R7943 were 2.6 and 2.1 μM against the release induced by acetylcholine and DMPP, respectively, indicating that the potency of SEA0400 is about a half of that of KB-R7943 in inhibiting the nicotinic receptor-mediated CA release. …
Journal of pharmacological sciences 91(3), 211-218, 2003-03-01
… 100 μM) inhibited CA secretion stimulated by acetylcholine (10 and 30 μM) and 1,1-dimethyl-4-phenyl-piperazinium (DMPP) (3 and 10 μM), but facilitated CA secretion stimulated by high K<sup>+</sup> …
Kosova - The Example of Peace in Balkans 17 February 2012. The Republic of Kosova celebrated the 4th anniversary of Independence. It was celebrated in Prishtina, and in Tirana as well. Kosova's Embassy in Tirana organized the ...