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any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)

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1. 大腸癌切除後のサーベイランス surveillance after colorectal cancer resection
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Patterns of medication initiation in newly diagnosed diabetes mellitus: quality and cost implications.

Desai NR, Shrank WH, Fischer MA, Avorn J, Liberman JN, Schneeweiss S, Pakes J, Brennan TA, Choudhry NK.SourceDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
The American journal of medicine.Am J Med.2012 Mar;125(3):302.e1-7.
OBJECTIVE: Six oral medication classes have been approved by the Food and Drug Administration for the treatment of type 2 diabetes. Although all of these agents effectively lower blood glucose, the evidence supporting their impact on other clinical events is variable. There also are substantial cost
PMID 22340932

He YL.SourceTranslational Medicine-Translational Science, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
Clinical pharmacokinetics.Clin Pharmacokinet.2012 Mar 1;51(3):147-62. doi: 10.2165/11598080-000000000-00000.
Vildagliptin is an orally active, potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor, shown to be effective and well tolerated in patients with type 2 diabetes mellitus (T2DM) as either monotherapy or in combination with other anti-diabetic agents. Vildagliptin possesses several desirable
PMID 22339447