アプリンジン
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2021/06/13 08:06:45」(JST)
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Aprindine |
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AHFS/Drugs.com | International Drug Names |
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ATC code | |
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{3-[2,3-dihydro-1H-inden-2-yl(phenyl)amino]propyl}diethylamine
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CAS Number | |
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PubChem CID | |
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DrugBank | |
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ChemSpider | |
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UNII | |
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KEGG | |
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ChEMBL | |
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CompTox Dashboard (EPA) | |
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Formula | C22H30N2 |
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Molar mass | 322.496 g·mol−1 |
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3D model (JSmol) | |
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c1cccc3c1CC(N(c2ccccc2)CCCN(CC)CC)C3
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InChI=1S/C22H30N2/c1-3-23(4-2)15-10-16-24(21-13-6-5-7-14-21)22-17-19-11-8-9-12-20(19)18-22/h5-9,11-14,22H,3-4,10,15-18H2,1-2H3 Y Key:NZLBHDRPUJLHCE-UHFFFAOYSA-N Y
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(verify) |
Aprindine is a Class 1b antiarrhythmic agent.[1]
References
- ^ WHOCC. "WHOCC - ATC/DDD Index". www.whocc.no. Retrieved 2018-03-01.
Antiarrhythmic agents (C01B) |
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Channel blockers | class I (Na+ channel blockers) | class Ia (Phase 0→ and Phase 3→) |
- Ajmaline
- Disopyramide
- Hydroquinidine
- Lorajmine
- Prajmaline
- Procainamide#
- Quinidine#
- Sparteine
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class Ib (Phase 3←) |
- IV
- enteral
- Aprindine
- Mexiletine
- Tocainide
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class Ic (Phase 0→) |
- Encainide‡
- Ethacizine
- Flecainide
- Indecainide‡
- Lorcainide
- Moracizine‡
- Propafenone
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class III (Phase 3→, K+ channel blockers) |
- Amiodarone
- Bretylium
- Bunaftine
- Celivarone†
- Dofetilide
- Dronedarone
- E-4031†
- Ibutilide
- Nifekalant
- Sotalol
- Tedisamil
- Vernakalant
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class IV (Phase 4→, Ca2+ channel blockers) | |
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Receptor agonists and antagonists | class II (Phase 4→, β blockers) |
- Nadolol
- Pindolol
- Propranolol
- cardioselective
- Acebutolol
- Atenolol
- Esmolol
- Metoprolol
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A1 agonist |
- Adenosine
- Benzodiazepines
- Barbiturates
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M2 |
- muscarinic antagonist: Atropine
- Disopyramide
- Quinidine
muscarinic agonist: Digoxin
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α receptors |
- Amiodarone
- Bretylium
- Quinidine
- Verapamil
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Ion transporters | Na+/ K+-ATPase |
- Digitoxin
- Digoxin
- Ouabain
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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English Journal
Japanese Journal
- 心室性期外収縮に対する Mexitil と Aspenon の抗不整脈効果の比較検討 : 連結期の長短の違いによる有効率(日本循環器学会 第57回中国・四国地方会)
★リンクテーブル★
[★]
- 英
- aprindine
- 化
- 塩酸アプリンジン aprindine hydrochloride
- 商
- アスペノン Aspenon、アプリトーン