WordNet

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Non-chemical proton-dependent steps prior to O2-activation limit Azotobacter vinelandii 3-mercaptopropionic acid dioxygenase (MDO) catalysis.

Crowell JK1, Sardar S1, Hossain MS1, Foss FW Jr1, Pierce BS2.
Archives of biochemistry and biophysics.Arch Biochem Biophys.2016 Aug 15;604:86-94. doi: 10.1016/j.abb.2016.06.009. Epub 2016 Jun 13.
3-mercaptopropionate dioxygenase from Azotobacter vinelandii (Av MDO) is a non-heme mononuclear iron enzyme that catalyzes the O2-dependent oxidation of 3-mercaptopropionate (3mpa) to produce 3-sulfinopropionic acid (3spa). With one exception, the active site residues of MDO are identical to bacteri
PMID 27311613

Nair P1, Hamzeh AR1, Mohamed M2, Saif F2, Tawfiq N2, El Halik M2, Al-Ali MT1, Bastaki F2.
American journal of medical genetics. Part A.Am J Med Genet A.2016 Aug;170(8):2127-32. doi: 10.1002/ajmg.a.37766. Epub 2016 May 27.
Microcephaly is a rare neurological condition, both in isolation and when it occurs as part of a syndrome. One of the syndromic forms of microcephaly is microcephaly, seizures and developmental delay (MCSZ) (OMIM #613402), a rare autosomal recessive neurodevelopmental disorder with a range of phenot
PMID 27232581

Structure-function characterization of the human mitochondrial thiamin pyrophosphate transporter (hMTPPT; SLC25A19): Important roles for Ile(33), Ser(34), Asp(37), His(137) and Lys(291).

Sabui S1, Subramanian VS1, Kapadia R1, Said HM2.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Aug;1858(8):1883-90. doi: 10.1016/j.bbamem.2016.05.011. Epub 2016 May 14.
Thiamin plays a critical role in cellular energy metabolism. Mammalian cells obtain the vitamin from their surroundings, converted it to thiamin pyrophosphate (TPP) in the cytoplasm, followed by uptake of TPP by mitochondria via a carrier-mediated process that involves the MTPPT (product of the SLC2
PMID 27188525