WordNet

a colorless crystalline organic base containing nitrogen; the parent compound of various biologically important substances
any of several bases that are derivatives of purine
being or containing a hydroxyl group

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CFTR silencing in pancreatic β-cells reveals a functional impact on glucose-stimulated insulin secretion and oxidative stress response.

Ntimbane T1, Mailhot G2, Spahis S2, Rabasa-Lhoret R3, Kleme ML2, Melloul D4, Brochiero E5, Berthiaume Y6, Levy E7.
American journal of physiology. Endocrinology and metabolism.Am J Physiol Endocrinol Metab.2016 Feb 1;310(3):E200-12. doi: 10.1152/ajpendo.00333.2015. Epub 2015 Dec 1.
Cystic fibrosis (CF)-related diabetes (CFRD) has become a critical complication that seriously affects the clinical outcomes of CF patients. Although CFRD has emerged as the most common nonpulmonary complication of CF, little is known about its etiopathogenesis. Additionally, whether oxidative stres
PMID 26625901

Peters B1, Ballmann C1, Mcginnis G1, Epstein E1, Hyatt H1, Slivka D2, Cuddy J3, Hailes W3, Dumke C3, Ruby B3, Quindry J1.
Journal of sports sciences.J Sports Sci.2016;34(1):56-66. doi: 10.1080/02640414.2015.1031164. Epub 2015 Apr 14.
Altitude exposure and exercise elicit oxidative stress in blood; however, exercise recovery at 5000 m attenuates oxidative stress. The purpose was to determine the altitude threshold at which blood oxidative stress is blunted during exercise recovery. Twelve males 18-28 years performed four-cycle er
PMID 25871479

Resa S1, Orte A2, Miguel D1, Paredes JM2, Puente-Muñoz V2, Salto R3, Giron MD3, Ruedas-Rama MJ2, Cuerva JM4, Alvarez-Pez JM2, Crovetto L5.
Chemistry (Weinheim an der Bergstrasse, Germany).Chemistry.2015 Oct 12;21(42):14772-9. doi: 10.1002/chem.201502799. Epub 2015 Sep 16.
The simultaneous detection of relevant metabolites in living organisms by using one molecule introduces an approach to understanding the relationships between these metabolites in healthy and deregulated cells. Fluorescent probes of low toxicity are remarkable tools for this type of analysis of biol
PMID 26374264

An Efficient Synthesis of(±)-cis-2-Amino-6-hydroxy-9-[4'-hydroxyethyl-2'-cyclopenten-1'-yl]purine

池田至 [他],細川秀毅,示野貞夫,竹田正彦
日本水産学会誌 57(8), 1539-1542, 1991
… Hipoxanthine, nucleosides (inosine, adenosine, guanosine, uridine), nucleotides including adenosine 5'-monophosphate (AMP), ADP, ATP, IDP, ITP, GDP, GTP, xanthosine 5'-monophosphate, 3'-IMP, 3'-UMP, 2-deoxy-IMP, allyltio-IMP, and Trp-related compounds (D-Trp, DL-Trp, 5-hydroxy-Trp, 5-methyl-DL-Trp, tryptamine, 5-hydroxy-tryptamine, indolepropionic acid, indole-3-pyruvic acid, β-indolelactic acid, indole) were all ineffective. …
NAID 130001545410

天正明 [他],清水巖,竹縄忠臣,菊地博之,六城雅彙,紙谷孝
藥學雜誌 94(6), 708-716, 1974-06-25
… 2) Among the 6-substituted analogs, hydroxyamino compound was found to possess a high biological activity, equivalent to that of eritadenine. … Thus, basic substituents at the 6-position of the purine ring may be essential for the activity, as evidenced by the loss of activity of the 6-hydroxy, 6-mercapto, 6-chloro, and hydrogen compounds. …
NAID 110003651830