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- 16,16-dimethylprostaglandin E2
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English Journal
- Immunological tolerance in a mouse model of immune-mediated liver injury induced by 16,16 dimethyl PGE2 and PGE2-containing nanoscale hydrogels.
- Okamoto T, Saito T, Tabata Y, Uemoto S.SourceDepartment of Surgery Hepato-pancreatico-biliary and Transplantation, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
- Biomaterials.Biomaterials.2011 Jul;32(21):4925-35. Epub 2011 Apr 8.
- Although immunosuppressive agents play a pivotal role in the success of organ transplantation, chronic toxicity has been a major issue for long-term treatment. The development of therapies that induce donor-specific immunological tolerance remains an important clinical challenge. In the present stud
- PMID 21477856
- cAMP inhibits modulation of airway smooth muscle phenotype via the exchange protein activated by cAMP (Epac) and protein kinase A.
- Roscioni SS, Dekkers BG, Prins AG, Menzen MH, Meurs H, Schmidt M, Maarsingh H.SourceDepartment of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands. s.s.roscioni@rug.nl
- British journal of pharmacology.Br J Pharmacol.2011 Jan;162(1):193-209. doi: 10.1111/j.1476-5381.2010.01011.x.
- BACKGROUND AND PURPOSE: Changes in airway smooth muscle (ASM) phenotype may contribute to the pathogenesis of airway disease. Platelet-derived growth factor (PDGF) switches ASM from a contractile to a proliferative, hypo-contractile phenotype, a process requiring activation of extracellular signal-r
- PMID 20804494
Japanese Journal
- Nitric Oxide Donating Compounds Inhibit HCl-Induced Gastric Mucosal Lesions Mainly via Prostaglandin
- UCHIDA Masayuki,MATSUEDA Kei,SHODA Ryosuke,MURAOKA Akira,YAMATO Shigeru
- The Japanese journal of pharmacology 85(2), 133-138, 2001-02-01
- … 16,16-Dimethyl PGE2 (0.3 - 3 μg/kg, p.o.; … dim-PGE2), sodium nitrite (0.3 and 1 mg/kg, s.c.) and sodium nitroprusside (30 and 100 μg/kg, i.v.; … The gastroprotective action by dim-PGE2 was not affected by the pre-treatment with NG-nitro-L-arginine methylester (10 mg/kg, i.v.). …
- NAID 10007119811
- A new method of separation and quantitation of mucus glycoprotein in rat gastric mucus gel layer and its application to mucus secretion induced by 16, 16-dimethyl PGE_2
Related Links
- 16,16-dimethyl PGE2. Formal Name, 9-?oxo-?11α,?15R-?dihydroxy-?16,?16-?dimethyl- ?prosta-?5Z,?13E-?dien-?1-?oic acid. CAS Number, 39746-25-3. Molecular Formula, C22H36O5. Formula Weight, 380.5. Formulation, A solution in methyl acetate ...
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