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1. 甲状腺機能亢進症の心血管系への影響cardiovascular effects of hyperthyroidism [show details]
…cardiac myocyte. The subsequent binding of the T3-receptor complexes to DNA regulates the expression of genes, specifically those regulating calcium cycling in the cardiac myocyte . T3 may also have non-nuclear …
2. 心臓の再灌流障害reperfusion injury of the heart [show details]
…ischemic myocyte is viable but vulnerable to further injury if blood flow is restored (ie, reperfusion injury). Restoration of blood flow is associated with three events that may further injure myocytes: Microvascular… shown to reduce infarct size in preclinical models . In the phase 2 SOLSTICE trial, 535 patients with non-ST elevation MI were randomly assigned to losmapimod or placebo given within 12 hours and continued …
3. 非尿路上皮膀胱癌non urothelial bladder cancer [show details]
… Bladder cancers are categorized as urothelial and non-urothelial types. Non-urothelial bladder cancers are further classified as epithelial or non-epithelial. Approximately 90 percent of these cancers …
4. 急性冠症候群がない患者にでの心筋トロポニン濃度の上昇elevated cardiac troponin concentration in the absence of an acute coronary syndrome [show details]
… circulation without myocyte necrosis. There are other mechanisms not associated with cell death that could lead to troponin release into the circulation: Increased myocyte membrane permeability… major categories: myocardial damage related to supply-demand mismatch, myocardial damage related to non-ischemic causes (eg, myocarditis or direct trauma), and myocardial injury that is multifactorial or …
5. 成人における全身性エリテマトーデスの冠動脈疾患以外の心症状non coronary cardiac manifestations of systemic lupus erythematosus in adults [show details]
… This topic review will focus on the non-coronary artery disease-related cardiac disorders associated… The characteristic findings of hydroxychloroquine toxicity on light microscopy are diffuse myocyte vacuolization without myocarditis,…