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1. 成人における発熱の病態生理および治療pathophysiology and treatment of fever in adults [show details]
…"nonshivering thermogenesis." At birth, highly thermogenic brown fat is present but rapidly decreases within the neonatal period. It is unclear how much brown fat remains as a source of heat production in the adult…
2. 肥満：遺伝的影響と病態生理obesity genetic contribution and pathophysiology [show details]
3. 後期早産児late preterm infants [show details]
…they have less white adipose tissue for insulation, cannot generate heat as effectively from brown adipose tissue, and lose heat more readily due to their larger ratio of surface area to weight . The risk…
4. 甲状腺ホルモンの作用thyroid hormone action [show details]
…Dio1 activity is reduced in hypothyroidism. Type 2 5'-deiodinase (Dio2) is expressed primarily in brown fat, pituitary, and cerebral cortex in rodents. It is more widely expressed in humans, including the …
5. レイノー現象の病因pathogenesis of raynaud phenomenon [show details]
…severe cold exposure, heat is generated by thermogenesis via shivering and by subcutaneous brown adipose tissue . Local skin cooling triggers both immediate vasoconstriction and subsequent neural signals …