房室管
WordNet
- the quantity contained in a can (同)canful
- preserve in a can or tin; "tinned foods are not very tasty" (同)tin, put_up
- airtight sealed metal container for food or drink or paint etc. (同)tin, tin_can
- a buoy with a round bottom and conical top (同)can buoy
- provide (a city) with a canal (同)canalize, canalise
- long and narrow strip of water made for boats or for irrigation
- (astronomy) an indistinct surface feature of Mars once thought to be a system of channels; they are now believed to be an optical illusion
- relating to or affecting the atria and ventricles of the heart; "atrioventricular disease" (同)auriculoventricular
PrepTutorEJDIC
- 《能力》『…することができる』 《可能性・推量》 《平叙文で》『…であり得る』 し得る,かもしれない 《否定文で》…のはずがない,ではあり得ない 《疑問文で》いったい…だろうか 《話》《許可・軽い命令》『…してもよい』 …してあげよう;《疑問文で》…してくれませんか
- 『かん』(取っ手・ふた・口のついた金属・プラスチック製容器・コップなど) / 《米》(かん詰めの)『かん』,かん詰め(《英》 tin) / かん1杯(の…)《+『of』+『名』》 / …'を'かん詰めにする(また《英》 『tin』) / 《米俗》…'を'くびにする
- canceled / cancellation / canon / canto
- 『運河』 / (食道・気菅などの)導菅 / (火星の苗面に見える)運河状の地形
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/05/08 21:26:24」(JST)
[Wiki en表示]
The proper development of the atrioventricular canal into its prospective components (The heart septum and associated valves) to create a clear division between the four compartments of the heart and ensure proper blood movement through the heart, are essential for proper heart function. When this process does not happen correctly, a child will develop atrioventricular canal defect which occurs in 2 out of every 10,000 births.[1] It also has a correlation with Down Syndrome because 20% of children with Down Syndrome suffer from atrioventricular canal disease as well. This is a very serious condition and surgery is necessary within the first six months of life for a child.[2] Half of the children who are untreated with this condition die during their first year due to heart failure or pneumonia.[3]
Atrioventricular canal defect is a combination of abnormalities of the heart and is present at birth. There is a problem when there are holes present in the walls that separate chambers (septa),as well as when valves are incorrectly constructed. There are other names for these heart abnormalities such as endocardial cushion defects or atrioventricular septal defect[4]
Contents
- 1 Development
- 2 Clinical relevance
- 2.1 Atrioventricular canal defect
- 3 See also
- 4 References
Development
A photo of the basic anatomical structures of the heart. During normal heart development all four chambers are separated and the mitral and tricupsid valves are properly developed.
In a normal healthy heart there are four chambers. This consists of right and left atria, and right and left ventricles. The right atrium and right ventricle function to pump blood to the lungs while the left atrium and left ventricle pump blood to the rest of the body. There are valves in place that inhibit back-flow between these chambers.[4]
Clinical relevance
Atrioventricular canal defect
This is an echocardiography of "Complete" Atriventricular Canal Disorder. There is a clear absence of lower septum that would separate all four chambers of the heart
Main article: atrioventricular canal defect
This defect is developed because of the improper formation of the endocardial cushions, and their job is to separate the different parts of the heart during development when they fuse. It is strongly associated with Down's syndrome. The structures that develop from the fusion of the endocardial cushions are:
- The Atrial septum- this structure divides the left and right atrium
- The Ventricular septum-this structure divides the left and right ventricles.
- The Mitral Valve and tricuspid valve - these valves are formed by the proper division of an early common valve being separated into two.[5]
Atrioventricular canal defect may be divided into partial or complete forms. In the partial form, openings between the left and right atria and improper formation of the mitral valve exist. In the complete form, there is free movement in all chambers because there is a large hole where the atria and ventricles meet, and instead of there being two valves there is one common valve.[4]
Surgery is usually conducted in-between the 3rd and 6th month of life, and with this condition the earlier the better. Usually, intracardiac repair involves closing the holes in the septum and the creation of two new atrioventricular valves from the underdeveloped common valve leaflet.[3]
See also
- Atrioventricular septal defect
- Atrioventricular septum
References
- ^ "Orphanet: Complete atrioventricular canal". www.orpha.net. Retrieved 2015-10-09.
- ^ Brown, David MD "Atrioventricular Canal Defect" Children's Hospital Boston 20120 http://www.childrenshospital.org/az/Site521/mainpageS521P0.html
- ^ a b Calabro, Raffaele & Limongelli, Giuseppe "Complete Atrioventricular Canal" 2006 April 5, US National Library of Medicine National Institutes of Health http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459121/
- ^ a b c Mayo Clinic September 12, 2012"Atrioventricular Canal Defect" http://www.mayoclinic.com/health/atrioventricular-canal-defect/DS00745
- ^ Cincinnati Children's Hospital "Atrioventricular Septal Defect" April 2010 http://www.cincinnatichildrens.org/health/a/avsd/
UpToDate Contents
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English Journal
- A Notch-dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion.
- Chang AC1, Garside VC, Fournier M, Smrz J, Vrljicak P, Umlandt P, Fuller M, Robertson G, Zhao Y, Tam A, Jones SJ, Marra MA, Hoodless PA, Karsan A.
- Developmental dynamics : an official publication of the American Association of Anatomists.Dev Dyn.2014 Jul;243(7):894-905. doi: 10.1002/dvdy.24127. Epub 2014 Apr 17.
- Background: Valvuloseptal defects are the most common congenital heart defects. Notch signaling-induced endothelial-to-mesenchymal transition (EMT) in the atrioventricular canal (AVC) cushions at murine embryonic day (E)9.5 is a required step during early valve development. Insights to the transcrip
- PMID 24633789
- Lifetime Prevalence of Congenital Heart Disease in the General Population from 2000 to 2010.
- Marelli AJ1, Ionescu-Ittu R2, Mackie AS3, Guo L2, Dendukuri N4, Kaouache M2.
- Circulation.Circulation.2014 Jun 18. pii: CIRCULATIONAHA.113.008396. [Epub ahead of print]
- BACKGROUND: -Our objective was to obtain contemporary life-time estimates of CHD prevalence using population based data sources up to year 2010.METHODS AND RESULTS: -The Quebec CHD database contains 28 years of longitudinal data on all individuals with CHD from 1983-2010. Severe CHD was defined as t
- PMID 24944314
- Holt-Oram syndrome with intermediate atrioventricular canal defect, and aortic coarctation: functional characterization of a de novo TBX5 mutation.
- Baban A1, Pitto L, Pulignani S, Cresci M, Mariani L, Gambacciani C, Digilio MC, Pongiglione G, Albanese S.
- American journal of medical genetics. Part A.Am J Med Genet A.2014 Jun;164A(6):1419-24. doi: 10.1002/ajmg.a.36459. Epub 2014 Mar 24.
- Holt-Oram syndrome (HOS) is a rare autosomal dominant disorder characterized by upper limb defects and congenital heart defects (CHD), which are often simple septal and conduction defects, less frequently complex CHDs. We report on a 9 year-old boy with clinical and radiologic features of HOS consis
- PMID 24664498
Japanese Journal
- 胎児心臓超音波スクリーニング検査で発見された心疾患症例と見逃された症例の検討
- 山下 美智子,日高 庸博,林 周作,入江 明美,宮城 晶子,河津 由紀子,稲村 昇,萱谷 太,石井 桂介,光田 信明
- Pediatric Cardiology and Cardiac Surgery 30(2), 166-172, 2014
- 目的:胎児心臓超音波スクリーニングで発見された心疾患症例と見逃された症例を検討し,検査の効果と問題点を検証すること.方法:2008年4月~2012年3月に,当院で胎児超音波スクリーニングを受け分娩に至ったローリスク単胎妊婦を対象とした.検査陽性症例および偽陰性症例の内訳を診療録より後方視的に検討した.検査は妊娠18週前後,28週前後,36週前後の3回行った.結果:対象期間の検査のべ回数は9,983 …
- NAID 130003398252
- 山岸 敬幸
- Pediatric Cardiology and Cardiac Surgery 29(2), 68-74, 2013
- 房室中隔は右心房と左心室を隔て, 心房中隔と心室中隔に連なる組織である. 房室中隔は房室管の心内膜床から発生する. 原始心筒がloopingし, 心房・心室が形態的に明らかになる頃, 房室管部では心ゼリーが残存・増生する. 心内膜から上皮間葉転換により遊離して形質転換した間葉系細胞が, その心ゼリーの中に侵入し, 心内膜床が形成される. 心内膜床は, 主に上方(背側)および下方(腹側)から隆起して …
- NAID 130003380017
- Traditional Single Patch Versus the "Australian" Technique for Repair of Complete Atrioventricular Canal Defects
- HALIT VELIT,OKTAR GURSEI LEVENT,IMREN VELI YILDIRIM,IRIZ ERKAN,ERER DILEK,KULA SERDAR,TUNAOGLU FATMA SEDEF,GOKGOZ LEVENT,OLGUNTURK RANA
- Surgery today : the Japanese journal of surgery 38(11), 999-1003, 2008-11-01
- NAID 10024429098
Related Links
- The American Heart Association explains the congenital heart defect complete atrioventricular, AV, canal, complete AV canal, complete common AV canal, and endocardial cushion defect in children and adults. Essentially, they all ...
- Atrioventricular canal defect — Comprehensive overview covers symptoms, complications, treatment of this congenital heart defect. ... Atrioventricular canal defect is a combination of heart problems resulting in a defect in the center ...
★リンクテーブル★
[★]
- 英
- atrioventricular canal, AVC
- 関
- 原始心臓
[★]
房室管 atrioventricular canal
[★]
- 英
- atrioventricular canal
[★]
- (過去could)
- (可能)~できる、~しようと思えばできる、~する能力がある。
- (推量)~する可能性がある、~することがあり得る、~する/になることがある、~しない/にならないとも限らない。
- (許可)~してもよい、~しても差し支えない。
- 関
- able、feasible、possible
[★]
- 関
- conduit、duct、ductal、ductus、meatus、pipe、tubal、tube、vas、vessel
[★]
- 関
- AV