- alter、alteration、become、change、come、convolution、get、go、in turn、order、rank order、revolution、revolve、roll、rolling、rotate、rotation、rotatory、round、shift、turn to、turning、variation、variational
- good turn
- turn of events, twist
- move around
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/06/24 10:09:06」(JST)[Wiki en表示]
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 糖尿病患者の易感染性 susceptibility to infections in persons with diabetes mellitus
- 2. インスリン作用 insulin action
- 3. 本態性高血圧の病因における低出生体重の潜在的役割 possible role of low birth weight in the pathogenesis of essential hypertension
- 4. 高齢者における歩行障害 gait disorders of elderly patients
- 5. 感染性心内膜炎における疣贅形成の病態 pathogenesis of vegetation formation in infective endocarditis
- A novel fluorescent nanosensor for detection of heparin and heparinase based on CuInS2 quantum dots.
- Liu Z1, Ma Q1, Wang X2, Lin Z1, Zhang H1, Liu L1, Su X3.Author information 1Department of Analytical Chemistry, College of Chemistry, Jilin University, Changchun 130012, China.2Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 230022, China.3Department of Analytical Chemistry, College of Chemistry, Jilin University, Changchun 130012, China. Electronic address: firstname.lastname@example.org.AbstractIn this work, a novel fluorescence "turn off-on" nanosensor for the determination of heparin and heparinase based on CuInS2 quantum dots (QDs) was established. CuInS2 QDs (modified by l-cysteine) featuring amino groups were directly prepared in aqueous solution via a hydrothermal synthesis method. The amino groups on the surface of CuInS2 QDs can interact with sulfate and carboxylate groups in heparin via electrostatic interactions and hydrogen bonding, which led the fluorescence of CuInS2 QDs to "turn-off". However, the heparin could be hydrolyzed into small fragments in the presence of heparinase, which resulted in the fluorescence of CuInS2 QDs being recovered. Therefore, the addition of heparinase to the heparin/CuInS2 QDs system activated the fluorescence of CuInS2 QDs to "turn-on" state. Thus, the determination of heparin and heparinase could be achieved by monitoring the fluorescence "turn off-on". Under the optimum conditions, there was a good linear relationship between I/I0 (I and I0 were the fluorescence intensity of CuInS2 QDs in the presence and absence of heparin, respectively) and heparin concentration in the range of 0.05-15μmolL(-1) with the detection limit of 12.46nmolL(-1). The linear detection for heparinase was in the range of 0.2-5μgmL(-1) with the detection limit of 0.07μgmL(-1). The proposed nanosensor was employed for the detection of heparin in fetal bovine serum samples with satisfactory results.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Apr 15;54:617-22. doi: 10.1016/j.bios.2013.11.050. Epub 2013 Nov 25.
- In this work, a novel fluorescence "turn off-on" nanosensor for the determination of heparin and heparinase based on CuInS2 quantum dots (QDs) was established. CuInS2 QDs (modified by l-cysteine) featuring amino groups were directly prepared in aqueous solution via a hydrothermal synthesis method. T
- PMID 24333933
- Biosensing enhancement using passive mixing structures for microarray-based sensors.
- Lynn NS Jr1, Martínez-López JI2, Bocková M1, Adam P1, Coello V3, Siller HR4, Homola J5.Author information 1Institute of Photonics and Electronics, Chaberská 57, 18251 Prague, Czech Republic.2Tecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, C.P. 64849 Monterrey, N.L., México. Electronic address: email@example.comCentro de Investigación Científica y de Educación Superior de Ensenada, Unidad Monterrey, Alianza Sur No. 105, Nueva Carretera Aeropuerto Km 9.5, Apodaca 66629, N.L., México. Electronic address: firstname.lastname@example.orgTecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, C.P. 64849 Monterrey, N.L., México. Electronic address: email@example.comInstitute of Photonics and Electronics, Chaberská 57, 18251 Prague, Czech Republic. Electronic address: firstname.lastname@example.org.AbstractThe combination of microarray technologies with microfluidic sample delivery and real-time detection methods has the capability to simultaneously monitor 10-1000s of biomolecular interactions in a single experiment. Despite the benefits that microfluidic systems provide, they typically operate in the laminar flow regime under mass transfer limitations, where large analyte depletion layers act as a resistance to analyte capture. By locally stirring the fluid and delivering fresh analyte to the capture spot, the use of passive mixing structures in a microarray environment can reduce the negative effects of these depletion layers and enhance the sensor performance. Despite their large potential, little attention has been given to the integration of these mixing structures in microarray sensing environments. In this study, we use passive mixing structures to enhance the mass transfer of analyte to a capture spot within a microfluidic flow cell. Using numerical methods, different structure shapes and heights were evaluated as means to increase local fluid velocities, and in turn, rates of mass transfer to a capture spot. These results were verified experimentally via the real-time detection of 20-mer ssDNA for an array of microspots. Both numerical and experimental results showed that a passive mixing structure situated directly over the capture spot can significantly enhance the binding rate of analyte to the sensing surface. Moreover, we show that these structures can be used to enhance mass transfer in experiments regarding an array of capture spots. The results of this study can be applied to any experimental system using microfluidic sample delivery methods for microarray detection techniques.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Apr 15;54:506-14. doi: 10.1016/j.bios.2013.11.027. Epub 2013 Nov 25.
- The combination of microarray technologies with microfluidic sample delivery and real-time detection methods has the capability to simultaneously monitor 10-1000s of biomolecular interactions in a single experiment. Despite the benefits that microfluidic systems provide, they typically operate in th
- PMID 24321884
- Additive effect of the AZGP1, PIP, S100A8 and UBE2C molecular biomarkers improves outcome prediction in breast carcinoma.
- Parris TZ, Kovács A, Aziz L, Hajizadeh S, Nemes S, Semaan M, Forssell-Aronsson E, Karlsson P, Helou K.Author information Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Cancer Center, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.AbstractThe deregulation of key cellular pathways is fundamental for the survival and expansion of neoplastic cells, which in turn can have a detrimental effect on patient outcome. To develop effective individualized cancer therapies, we need to have a better understanding of which cellular pathways are perturbed in a genetically defined subgroup of patients. Here, we validate the prognostic value of a 13-marker signature in independent gene expression microarray datasets (n = 1,141) and immunohistochemistry with full-faced FFPE samples (n = 71). The predictive performance of individual markers and panels containing multiple markers was assessed using Cox regression analysis. In the external gene expression dataset, six of the 13 genes (AZGP1, NME5, S100A8, SCUBE2, STC2 and UBE2C) retained their prognostic potential and were significantly associated with disease-free survival (p < 0.001). Protein analyses refined the signature to a four-marker panel [AZGP1, Prolactin-inducible protein (PIP), S100A8 and UBE2C] significantly correlated with cycling, high grade tumors and lower disease-specific survival rates. AZGP1 and PIP were found in significantly lower levels in invasive breast tissue as compared with adjacent normal tissue, whereas elevated levels of S100A8 and UBE2C were observed. A predictive model containing the four-marker panel in conjunction with established clinical variables outperformed a model containing the clinical variables alone. Our findings suggest that deregulated AZGP1, PIP, S100A8 and UBE2C are critical for the aggressive breast cancer phenotype, which may be useful as novel therapeutic targets for drug development to complement established clinical variables.
- International journal of cancer. Journal international du cancer.Int J Cancer.2014 Apr 1;134(7):1617-29. doi: 10.1002/ijc.28497. Epub 2013 Oct 12.
- The deregulation of key cellular pathways is fundamental for the survival and expansion of neoplastic cells, which in turn can have a detrimental effect on patient outcome. To develop effective individualized cancer therapies, we need to have a better understanding of which cellular pathways are per
- PMID 24114735
- The impact of varying post-operative dressing size on recovery from laparoscopic cholecystectomy.
- Heinrich M, Ogden J, Patel AG.Author information a Faculty of Arts and Human Sciences, School of Psychology , University of Surrey , Guildford , UK.AbstractThis study aimed to explore the impact of the size of a post-operative dressing and the subsequent visibility of the wound on recovery from laparoscopic cholecystectomy (LC). A randomised controlled trial was conducted. Fourty-one patients (8 men and 33 women, mean age = 44 years) scheduled for LC were included. Participants were randomly assigned to receive either small gauze dressings (n = 19) or large gauze dressings (n = 22) which were directly applied on post-operative incisions. Patients' mood, psychological well-being, illness cognitions, and pain and recovery were assessed at three time points: baseline, immediately after the procedure and then two weeks later. The findings suggest that the management of post-surgical incisions influences patients' interpretation of their illness which in turn has an impact upon the process of recovery from LC. This implies that visual information available to patients after the procedure through the cognitive and emotional mechanisms involved in their processing can alter the process of convalescence from LC.
- Psychology, health & medicine.Psychol Health Med.2014 Apr;19(2):222-34. doi: 10.1080/13548506.2013.793368. Epub 2013 May 7.
- This study aimed to explore the impact of the size of a post-operative dressing and the subsequent visibility of the wound on recovery from laparoscopic cholecystectomy (LC). A randomised controlled trial was conducted. Fourty-one patients (8 men and 33 women, mean age = 44 years) scheduled fo
- PMID 23650880
- 保育者養成における音楽授業科目に関する一考察（2） ─本学の 1 年次秋学期から 2 年次春学期までの器楽関連科目について─
- こども教育宝仙大学紀要 7, 13-24, 2016-03-11
- NAID 120005719376
- Theoretical and applied linguistics at Kobe Shoin : トークス 19, 29-41, 2016-03-05
- NAID 120005717329
- Turn-on analysis of silicon insulated gate bipolar transistors with emitter trenches
- Jpn. J. Appl. Phys. 55(4S), 04ER04, 2016-02-29
- NAID 150000112010
- 自閉症の子どものための動作法 : 発達段階とそれに応じた支援
- 熊本大学教育実践研究 33, 45-55, 2016-02-29
- NAID 110010008264
- Go Cross-Channel with Confidence. Multi-channel advertising has never been so easy to manage — or so powerful. LEARN HOW. FBX is here. We help you. Join the Revolution. Leadership. Go Cross-Channel. Turn Goes Mobile- Friendly.
- ターンは国道2号線沿いのトラックショップ。ハンドルカバー、カーテンなど、オリジナルの トラック用品、カー用品の製造、ショップ販売、通信販売を行っています。
- TURN（Traversal Using Relay NAT）とは、NATやファイアーウォールの背後にある 要素が、TCP,UDP接続上でNATの外側からのデータを受信することを可能にする インターネットプロトコルである。 TURNは、単一のピアとの通信において受信側の端末 にな ...
- roll up
- go game
- go away, depart
- alter、alteration、alternate、convert、modification、modify、replacement、shift、switch、turn、turn to、variation、variational、vary
- flesh out, fill out
- daily round
- unit of ammunition, one shot
- round of drinks
- labialize, labialise
- get under one''s skin
- income tax return, return