出典: meddic

プロスタグランジン prostaglandins PG

WordNet   license wordnet

「a potent substance that acts like a hormone and is found in many bodily tissues (and especially in semen); produced in response to trauma and may affect blood pressure and metabolism and smooth muscle activity」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/07/01 00:37:37」(JST)

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  • Prostaglandin E2 inhibits IL-23 and IL-12 production by human monocytes through down-regulation of their common p40 subunit.
  • Kalim KW, Groettrup M.SourceDivision of Immunology, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.
  • Molecular immunology.Mol Immunol.2013 Mar;53(3):274-82. doi: 10.1016/j.molimm.2012.08.014. Epub 2012 Sep 14.
  • The heterodimeric cytokine IL-23 is important for the maintenance of Th17 cells, which are pivotal mediators of autoimmune diseases like rheumatoid arthritis, colitis, and multiple sclerosis. Prostaglandin E2 (PGE2) is a soluble regulator of inflammation that has both pro- and anti-inflammatory prop
  • PMID 22982753
  • α-Tocopherol (vitamin E) stimulates cyclic AMP production in human peripheral mononuclear cells and alters immune function.
  • Salinthone S, Kerns AR, Tsang V, Carr DW.SourceDepartment of Veterans Affairs Medical Center, VA Medical Center, Portland, OR 97239, USA.
  • Molecular immunology.Mol Immunol.2013 Mar;53(3):173-8. doi: 10.1016/j.molimm.2012.08.005. Epub 2012 Sep 1.
  • α-Tocopherol, the most biologically active member of the vitamin E family of fat soluble compounds, exhibits both antioxidant and anti-inflammatory properties. However, its mechanisms of action are not fully understood. Here, we show that, unlike other antioxidants, α-tocopherol stimulates the pro
  • PMID 22947771
  • Effect of body-weight loading onto the articular cartilage on the occurrence of quinolone-induced chondrotoxicity in juvenile rats.
  • Goto K, Imaoka M, Goto M, Kikuchi I, Suzuki T, Jindo T, Takasaki W.SourceMedicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 1-16-13 Kita-Kasai, Edogawa-ku, Tokyo 134-8630, Japan. Electronic address:
  • Toxicology letters.Toxicol Lett.2013 Feb 4;216(2-3):124-9. doi: 10.1016/j.toxlet.2012.11.017. Epub 2012 Nov 29.
  • The effect of body-weight loading onto the articular cartilage on the occurrence of chondrotoxicity was investigated in male juvenile Sprague-Dawley rats given ofloxacin (OFLX) orally once at 900mg/kg. Just after dosing of OFLX, hindlimb unloading was performed for 0, 2, 4, or 8h by a tail-suspensio
  • PMID 23201441
  • Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: Plausible role of NF-κB.
  • Rehman MU, Tahir M, Khan AQ, Khan R, Lateef A, Oday-O-Hamiza, Qamar W, Ali F, Sultana S.SourceSection of Molecular Carcinogenesis and Chemoprevention, Department of Medical Elementology and Toxicology, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.
  • Toxicology letters.Toxicol Lett.2013 Feb 4;216(2-3):146-58. doi: 10.1016/j.toxlet.2012.11.013. Epub 2012 Nov 27.
  • Flavonoid family is a rich source of polyphenolic compounds and hence possess strong antioxidant and anti inflammatory properties. The aim of this study was to determine the efficacy of chrysin; a bio-active flavonoid as an anticancer agent. Renal cancer was initiated by single intraperitoneal (i.p.
  • PMID 23194824


  • Chimyl Alcohol Suppresses PGE<sub>2</sub> Synthesis by Human Epidermal Keratinocytes through the Activation of PPAR-γ
  • <b>Effect of Ga-Al-As Laser Irradiation at Wavelengths of 660 or 810 nm with Constant Output on the Ability of Human Dental Pulp to Form Hard Tissue </b>
  • International Journal of Oral-Medical Sciences 16(3-4), 54-61, 2018
  • NAID 130006415694
  • <b>Effect of Prostaglandin E<sub>2 </sub>on Human Dental Follicle Cells during Osteogenic </b><b>Differentiation </b>
  • International Journal of Oral-Medical Sciences 16(3-4), 39-48, 2018
  • NAID 130006415691
  • Preventive effect of <i>Dioscorea japonica</i> on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E<sub>2</sub> synthetic pathway
  • Journal of Clinical Biochemistry and Nutrition 62(2), 139-147, 2018
  • NAID 130006407477


Description Prostaglandin D2.PNGFile:Prostaglandin retro23.png - Wikimedia Prostaglandins E, Synthetic (Prostaglandin Prostaglandin E2 - Wikipedia, the free Prostaglandin E2 - Wikipedia, the free pathways of prostaglandinsProstaglandin E3 - Wikipedia, the free tổng hợp prostaglandin prostaglandin

拡張検索6-ketoprostaglandin F1alpha」「prostaglandin F2 alpha」「prostaglandin F2alpha」「prostaglandin F2α



prostaglandin, PG



  • AHDは腎臓の様々な細胞・組織(ヘンレループ太い上行脚、集合管、腎髄質の間質、糸球体メサンギウム)でプロスタグランジンの産生を誘導する。ここで産生されたプロスタグランジンはADHの小売り様作用と血管に対する作用の両方を阻害する。抗利尿作用はADHによりGi,Gqを介したcAMP産生の抑制による。プロスタグランジンは局所に作用しADHが過剰に働かないように振る舞う。
→ NSAIDと腎障害の関係 NSAID腎症




PrepTutorEJDIC   license prepejdic

「parental guidance(映画の観客指定で)親の認可[映画]」

6-ketoprostaglandin F1alpha」



6-keto-PGF1 alpha、6-keto-PGF1alpha

prostaglandin F2 alpha」

  [★] プロスタグランジンF2α

prostaglandin F2alpha」

  [★] プロスタグランジンF2α

prostaglandin F2α」

  [★] プロスタグランジンF2α


  [★] プロスタグランジン