- 関
- PGE2 receptor
WordNet
- a potent substance that acts like a hormone and is found in many bodily tissues (and especially in semen); produced in response to trauma and may affect blood pressure and metabolism and smooth muscle activity
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- the 5th letter of the Roman alphabet (同)e
- the base of the natural system of logarithms; approximately equal to 2.718282...
PrepTutorEJDIC
- =sense organ / 受信装置
- einsteiniumの化学記号
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/16 21:37:42」(JST)
[Wiki en表示]
The prostaglandin E2 (PGE2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin E2. They include the following proteins:
- Prostaglandin E2 receptor 1 (EP1) - PTGER1
- Prostaglandin E2 receptor 2 (EP2) - PTGER2
- Prostaglandin E3 receptor 3 (EP3) - PTGER3
- Prostaglandin E4 receptor 4 (EP4) - PTGER4
See also
- Eicosanoid receptor
- Prostaglandin D2 receptor
References
External links
- Prostaglandin E2 Receptors at the US National Library of Medicine Medical Subject Headings (MeSH)
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Membrane proteins, receptors: cell surface receptors
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| G protein-coupled receptor |
| Class A |
- Eicosanoid receptor (Prostaglandin receptor)
- Protease-activated receptor
- Neurotransmitter receptor
- Purinergic receptor
- Biogenic amine receptor
- Olfactory receptor
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| Class B |
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| Class C |
- Metabotropic glutamate receptor
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| Class D |
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| Class E |
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| Class F |
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| Ligand-gated ion channel |
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| Enzyme-linked receptor |
- Serine/threonine-specific protein kinase
- Receptor tyrosine kinase
- Guanylate cyclase
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| Other/ungrouped |
- Asialoglycoprotein receptor
- Tumor necrosis factor receptor
- Immunoglobulin superfamily
- N-Acetylglucosamine receptor
- Neuropilins
- Transferrin receptor
- EDAR
- Lipoprotein receptor-related protein
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- See also
- cell surface receptor deficiencies
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Index of signal transduction
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| Description |
- Intercellular
- neuropeptides
- growth factors
- cytokines
- hormones
- Cell surface receptors
- ligand-gated
- enzyme-linked
- G protein-coupled
- immunoglobulin superfamily
- integrins
- neuropeptide
- growth factor
- cytokine
- Intracellular
- adaptor proteins
- GTP-binding
- MAP kinase
- Calcium signaling
- Lipid signaling
- Pathways
- hedgehog
- Wnt
- TGF beta
- MAPK ERK
- notch
- JAK-STAT
- apoptosis
- hippo
- TLR
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Prostanoid signaling
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Receptor
(ligands) |
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Enzyme
(inhibitors) |
| Cyclooxygenase |
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| PGD2 synthase |
- Retinoids
- Selenium (selenium tetrachloride, sodium selenite, selenium disulfide)
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| PGE synthase |
HQL-79
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| PGF synthase |
Bimatoprost
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| PGI2 synthase |
Tranylcypromine
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| TXA synthase |
- Camonagrel
- Dazmegrel
- Dazoxiben
- Furegrelate
- Isbogrel
- Midazogrel
- Nafagrel
- Nicogrelate
- Ozagrel
- Picotamide
- Pirmagrel
- Ridogrel
- Rolafagrel
- Samixogrel
- Terbogrel
- U63557A
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| Others |
- Precursors: Linoleic acid
- γ-Linolenic acid (gamolenic acid)
- Dihomo-γ-linolenic acid
- Diacylglycerol
- Arachidonic acid
- Prostaglandin G2
- Prostaglandin H2
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See also: Leukotrienergics
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UpToDate Contents
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English Journal
- Unraveling the complexity of leukotriene and prostaglandin inflammatory signaling.
- Rael E1.
- The Journal of allergy and clinical immunology.J Allergy Clin Immunol.2016 Jan;137(1):299-300. doi: 10.1016/j.jaci.2015.09.003. Epub 2015 Oct 27.
- PMID 26518091
- Prostaglandin E receptor 4 inhibition restores UVB-induced downregulation of ATP2A2/SERCA2 in cultured normal human keratinocytes.
- Kamijo M1, Wada A2, Mineki R3, Sakanishi T4, Ikeda S5.
- Journal of dermatological science.J Dermatol Sci.2016 Jan;81(1):69-71. doi: 10.1016/j.jdermsci.2015.10.010. Epub 2015 Oct 28.
- PMID 26596216
- Tryptophan-2,3-dioxygenase is regulated by prostaglandin E2 in malignant glioma via a positive signaling loop involving prostaglandin E receptor-4.
- Ochs K1,2, Ott M1,2, Rauschenbach KJ1,2, Deumelandt K1,2, Sahm F3,4, Opitz CA1,5, von Deimling A3,4, Wick W1,6, Platten M1,2.
- Journal of neurochemistry.J Neurochem.2015 Dec 27. doi: 10.1111/jnc.13503. [Epub ahead of print]
- Malignant gliomas and other types of tumors generate a local immunosuppressive microenvironment, which prohibits an effective anti-tumor immune response and promotes tumor growth. Along with others, we have recently demonstrated that catabolism of the essential amino acid tryptophan via tryptophan-2
- PMID 26708701
Japanese Journal
- New evidence for the involvement of prostaglandin receptor EP4b in ovulation of the medaka, Oryzias latipes.
- Fujimori Chika,Ogiwara Katsueki,Hagiwara Akane,Takahashi Takayuki
- Molecular and cellular endocrinology 362(1-2), 76-84, 2012-10-15
- … A cDNA for a prostaglandin E(2) (PGE(2)) receptor subtype 4, EP4b (Ptger4b), was cloned from the medaka ovary. …
- NAID 120004650807
- Genetic variability of prostaglandin E2 receptor subtype EP4 gene in aspirin-intolerant chronic urticaria
- Palikhe Nami Shrestha,Sin Hye Jung,Kim Seung Hyun [他]
- Journal of human genetics 57(8), 494-499, 2012-08
- NAID 40019386478
- 内因性睡眠物質 (特集 睡眠と生活習慣病 : 基礎・臨床研究の最新知見)
Related Links
- Prostaglandin E receptor 2 (subtype EP2), 53kDa Identifiers Symbols PTGER2; EP2 External IDs OMIM: 176804 MGI: 97794 HomoloGene: 739 IUPHAR: EP 2 ChEMBL: 1881 GeneCards: PTGER2 Gene Gene Ontology • • • • • ...
- The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve ...
★リンクテーブル★
[★]
- 英
- prostaglandin E receptor
- 関
- プロスタグランジンE2受容体、プロスタグランジンE受容体
[★]
- 英
- prostaglandin E receptor
- 関
- プロスタグランジンEレセプター
[★]
プロスタグランジン prostaglandins PG
[★]
アインスタイニウム
- 関
- einsteinium
[★]
[★]
プロスタグランジン