platelet-activating factor

出典: meddic


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/06/08 01:06:15」(JST)

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  • PAFR in adipose tissue macrophages is associated with anti-inflammatory phenotype and metabolic homoeostasis.
  • Filgueiras LR1, Koga MM1, Quaresma PG2, Ishizuka EK1, Montes MB1, Prada PO3, Saad MJ2, Jancar S1, Rios FJ4.
  • Clinical science (London, England : 1979).Clin Sci (Lond).2016 Apr 1;130(8):601-12. doi: 10.1042/CS20150538. Epub 2016 Jan 19.
  • Metabolic dysfunction is associated with adipose tissue inflammation and macrophage infiltration. PAFR (platelet-activating factor receptor) is expressed in several cell types and binds to PAF (platelet-activating factor) and oxidized phospholipids. Engagement of PAFR in macrophages drives them tow
  • PMID 26785675
  • CYP3A5*3 and MDR1 C3435T are influencing factors of inter-subject variability in rupatadine pharmacokinetics in healthy Chinese volunteers.
  • Xiong Y1, Yuan Z2,3, Yang J2, Xia C2, Li X4, Huang S2, Zhang H2, Liu M2.
  • European journal of drug metabolism and pharmacokinetics.Eur J Drug Metab Pharmacokinet.2016 Apr;41(2):117-124. Epub 2014 Nov 27.
  • Rupatadine (RUP) is an oral antihistamine and platelet-activating factor antagonist and is shown as the substrate of CYP3A5 and P-gp. The significant interindividual differences of CYP3A5 and P-gp often cause bioavailability differences of some clinical drugs. The present study is aimed to evaluate
  • PMID 25427746
  • Platelet-activating factor receptor (PAFr) is upregulated in small airways and alveoli of smokers and COPD patients.
  • Shukla SD1, Muller HK1, Latham R1, Sohal SS1,2, Walters EH1.
  • Respirology (Carlton, Vic.).Respirology.2016 Apr;21(3):504-10. doi: 10.1111/resp.12709. Epub 2015 Dec 10.
  • BACKGROUND AND OBJECTIVE: PAFr is a cell adhesion site for specific bacteria, notably non-typeable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae. We previously published that PAFr expression is significantly upregulated in the large airways of smokers, especially in COPD. We have now in
  • PMID 26662379


  • 免疫学的特異性に基づいたヘパリン起因性血小板減少症(HIT)の適切な診断と治療
  • The Responses of Pulmonary and Systemic Circulation and Airway to Allergic Mediators in Anesthetized Rats
  • 2) 顆粒膜細胞における細胞内信号伝達系分子の活性化機序と排卵誘発への応用(シンポジウム1(生殖) 卵巣のダイナミックな変化の神秘に迫る-臨床へのフィードバックを目指して-,第67回日本産科婦人科学会学術講演会講演要旨)



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関連記事factor」「fact」「platelet」「activating」「activating factor



platelet activating factor platelet-activating factor, PAF


  [★] 血小板活性化因子, platelet activating factor, platelet-activating factor



  • n.

WordNet   license wordnet

「be a contributing factor; "make things factor into a company''s profitability"」

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「any of the numbers (or symbols) that form a product when multiplied together」

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「an independent variable in statistics」

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「anything that contributes causally to a result; "a number of factors determined the outcome"」

PrepTutorEJDIC   license prepejdic

「(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize」

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「consider as relevant when making a decision; "You must factor in the recent developments"」
factor in, factor out

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「resolve into factors; "a quantum computer can factor the number 15"」
factor in, factor out



  • n.
actualactuallyin factin practiceindeedpractically

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「an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"」

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「a concept whose truth can be proved; "scientific hypotheses are not facts"」

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「a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"」

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「a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"」

PrepTutorEJDIC   license prepejdic

「〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行」


  [★] 血小板

WordNet   license wordnet

「tiny bits of protoplasm found in vertebrate blood; essential for blood clotting」
blood platelet, thrombocyte



WordNet   license wordnet

「causing motion or action or change」

activating factor」