WordNet
- limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
- control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
- limit the range or extent of; "Contact between the young was inhibited by strict social customs"
- a soft thin (usually translucent) paper (同)tissue_paper
- part of an organism consisting of an aggregate of cells having a similar structure and function
- a substance that retards or stops an activity
PrepTutorEJDIC
- 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
- 〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》
- 〈U〉〈C〉(生物体の)『組織』 / 〈U〉〈C〉『薄織物』 / 〈U〉〈C〉水を吸収する柔らかな薄紙 / 〈C〉カーボンコピー用薄紙 / 〈C〉《a ~》(…を)織り交ぜて作ったもの《+of+名》 / =tissue paper
- 抑制する人(物) / 化学反応抑制剤
- OLD French古[代]フランス語
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/09 21:04:37」(JST)
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- 1. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations
- 2. 糸球体半月体形成の機序 mechanisms of glomerular crescent formation
- 3. 変形性関節症の病因 pathogenesis of osteoarthritis
- 4. 慢性関節リウマチにおける滑膜異常 synovial pathology in rheumatoid arthritis
- 5. 関節リウマチの病因 pathogenesis of rheumatoid arthritis
English Journal
- Alterations in enhancer of zeste homolog 2, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression are associated with ex vivo and in vitro bone metastasis in renal cell carcinoma.
- Wang J1, Ren Y1, Guo X1, Cheng H1, Ye Y1, Qi J1, Yang C1, You H1.
- Molecular medicine reports.Mol Med Rep.2015 May;11(5):3585-92. doi: 10.3892/mmr.2015.3164. Epub 2015 Jan 8.
- Renal cell carcinoma (RCC) has a high potential for bone metastasis; however, the molecular mechanisms underlying this metastasis have remained to be elucidated. The present study aimed to explore the expression levels of enhancer of zeste homolog 2 (EZH2), matrix metalloproteinase-2 (MMP2) and tis
- PMID 25571919
- Tissue inhibitor of metalloproteinase-3 (TIMP3) promotes endothelial apoptosis via a caspase-independent mechanism.
- Qi JH1, Anand-Apte B.
- Apoptosis : an international journal on programmed cell death.Apoptosis.2015 Apr;20(4):523-34. doi: 10.1007/s10495-014-1076-y.
- Tissue inhibitor of metalloproteinases-3 (TIMP3) is a tumor suppressor and a potent inhibitor of angiogenesis. TIMP3 exerts its anti-angiogenic effect via a direct interaction with vascular endothelial growth factor (VEGF) receptor-2 (KDR) and inhibition of proliferation, migration and tube formatio
- PMID 25558000
- Testosterone suppresses ventricular remodeling and improves left ventricular function in rats following myocardial infarction.
- Wang XF1, Qu XQ2, Zhang TT1, Zhang JF1.
- Experimental and therapeutic medicine.Exp Ther Med.2015 Apr;9(4):1283-1291. Epub 2015 Feb 6.
- Men with congestive heart failure (CHF) have relatively low testosterone levels. Several studies demonstrated that testosterone treatment increases cardiac output and reduces peripheral vascular resistance. However, the effects of testosterone on heart function, cardiomyocyte apoptosis and ventricul
- PMID 25780423
Japanese Journal
- ヒト歯髄由来線維芽細胞におけるIL-1β刺激によるMMP-3産生に及ぼすJNKの影響
- 加藤 侑,合田 征司,池尾 隆,林 宏行
- 日本歯科保存学雑誌 56(1), 48-54, 2013-02-28
- 目的:う蝕の進行に伴い,う蝕病原性細菌により歯髄組織に炎症が惹起される.炎症時の歯髄組織では炎症性サイトカインであるIL-1βが産生され,炎症の進行に伴いマトリックスメタロプロテアーゼ(MMPs)などのタンパク質分解酵素が産生される.特にMMP-3は,細胞外マトリックス分解能だけでなく,ほかのMMP-1, MMP-7, MMP-9を活性化し,歯髄組織を破壊進行し,炎症を進展することが知られている. …
- NAID 110009596781
- Expression and function of chemerin in synovial tissues of patients with rheumatoid arthritis
- 鏑木 誠,楠 夏子,高橋 寛,土谷 一晃,川合 眞一,遠藤 平仁
- 東邦医学会雑誌 60(1), 3-14, 2013-01
- … 原著Background: Chemerin is an adipokine that stimulates chemotaxis of cells involved in the innate immune system. … We evaluated the role of chemerin in inflammatory arthritides such as rheumatoid arthritis (RA) and osteoarthritis (OA). … In addition, the effect of chemerin on matrix metalloproteinase (MMP) production by cultured synovial cells was assessed. …
- NAID 120005306373
- Loss of Angiotensin-Converting Enzyme 2 Exacerbates Myocardial Injury via Activation of the CTGF-Fractalkine Signaling Pathway
- Song Bei,Zhang Zhen-Zhou,Zhong Jiu-Chang,Yu Xi-Yong,Oudit Gavin Y.,Jin Hai-Yan,Lu Lin,Xu Ying-Le,Kassiri Zamaneh,Shen Wei-Feng,Gao Ping-Jin,Zhu Ding-Liang
- Circulation Journal 77(12), 2997-3006, 2013
- … ACE2 deficiency triggered greater increases in the expression of connective tissue growth factor (CTGF), fractalkine (FKN) and phosphorylated ERK1/2 in AngII-treated ACE2KO hearts. … These changes were associated with greater activation of matrix metalloproteinase (MMP) 2, MMP9 and MT1-MMP and exacerbation of myocardial injury and dysfunction. …
- NAID 130003382154
Related Links
- The matrix metalloproteinases are inhibited by specific endogenous tissue inhibitors of metalloproteinases (TIMPs), which comprise a family of four protease inhibitors: TIMP1, TIMP2, TIMP3 and TIMP4. Overall, all MMPs are inhibited by TIMPs ...
- 内因性のMMP阻害因子としてTIMP(Tissue Inhibitor of Metalloproteinase)が知られ ている。TIMPはMMPと複合体を形成することによりMMPの活性を抑える働きをもって おり、過剰なMMPの作用発現による組織破壊を防いでいる。TIMPファミリーにはTIMP1- 4 ...
Related Pictures
★リンクテーブル★
「組織メタロプロテアーゼ阻害物質」
「組織性メタロプロテアーゼ阻害因子」
「マトリックスメタロプロテアーゼ阻害因子」
「tissue inhibitor of metalloproteinase-1」
- 関
- TIMP-1
「tissue inhibitor of metalloproteinase-2」
- 関
- TIMP-2
「tissue inhibitor of metalloproteinase-3」
- 関
- TIMP-3
「inhibit」
- v.
- 抑制する、阻害する、阻止する
- 関
- abrogate、block、depress、depression、deter、inhibition、interdict、prevent、prevention、repress、repression、restrain、restraint、suppress、suppression
「inhibitor」
- n.