WordNet

complicated in structure; consisting of interconnected parts; "a complex set of variations based on a simple folk melody"; "a complex mass of diverse laws and customs"
a compound described in terms of the central atom to which other atoms are bound or coordinated (同)coordination_compound
a conceptual whole made up of complicated and related parts; "the complex of shopping malls, houses, and roads created a new town" (同)composite
(psychoanalysis) a combination of emotions and impulses that have been rejected from awareness but still influence a persons behavior
secure against; "immune from taxation as long as he resided in Bermuda"; "immune from criminal prosecution"
a person who is immune to a particular infection
relating to or conferring immunity (to disease or infection) (同)resistant
(usually followed by `to'
relating to the condition of immunity; "the immune system"

PrepTutorEJDIC

『いくつかの部分から成る』,複合の,合成の / 『複雑な』,入りくんだ,こみいった(complicated) / 複合体,合成物 / コンプレックス,複合(抑圧されて心に残った複雑なしこり)
免疫の / 《補語にのみ用いて》(影響・攻撃・義務・税などを)免れている《+『against』(『from, to』)+『名』》

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/28 21:30:49」(JST)

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Immune complex diseases

An immune complex, sometimes called an antigen-antibody complex, is a molecule formed from the integral binding of an antibody to a soluble antigen.^[1] The bound antigen and antibody act as a unitary object, effectively an antigen of its own with a specific epitope. After an antigen-antibody reaction, the immune complexes can be subject to any of a number of responses, including complement deposition, opsonization,^[2] phagocytosis, or processing by proteases. Red blood cells carrying CR1-receptors on their surface may bind C3b-coated immune complexes and transport them to phagocytes, mostly in liver and spleen, and return to the general circulation.

Immune complexes may themselves cause illness when they are deposited in organs, for example, in certain forms of vasculitis. This is the third form of hypersensitivity in the Gell-Coombs classification, called type III hypersensitivity.^[3] Such hypersensitivity progressing to disease states produces the so-called immune complex diseases.

Immune complex deposition is a prominent feature of several autoimmune diseases, including systemic lupus erythematosus, cryoglobulinemia, rheumatoid arthritis, scleroderma and Sjögren's syndrome.^[4]^[5]

ReferencesEdit

^ Cush, John; Kavanaugh, Arthur; Stein, Charles (2005). Rheumatology: Diagnosis and Therapeutics. Lippincott Williams & Wilkins. p. 78. ISBN 9780781757324. |access-date= requires |url= (help)
^ Goldsby, Richard (2002). Immunology. Macmillan. p. 381. ISBN 9780716749479.
^ Barret, James (1980). Basic Immunology and its Medical Application (2 ed.). St.Louis: The C.V. Mosby Company. ISBN 0-8016-0495-8.
^ Lawley, Thomas; Moustopoulos, Haralampos (1979). "Demonstration of Circulating Immune Complexes in Sjögren's Syndrome". Journal of Immunology (The American Association of Immunologists) 123 (3): 1382–7. PMID 469255.
^ Wallace, Daniel, ed. (2004). The New Sjogren's Syndrome Handbook. Oxford University Press. p. 68. ISBN 9780198038481. |access-date= requires |url= (help)

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1. Acquired deficiencies of the complement system
2. 血清病および血清病様反応 serum sickness and serum sickness like reactions
3. 補体系の概要および臨床的評価 overview and clinical assessment of the complement system
4. リウマチ因子の発生および測定の有用性 origin and utility of measurement of rheumatoid factors
5. 癌免疫療法の原則 principles of cancer immunotherapy

English Journal

Characteristics of antibody responses in Pigeon Fanciers' Lung.

Nademi Z, Todryk S, Baldwin C.SourceDepartment of Biomedical Sciences, Faculty of Health & Life Sciences, Ellison Building, Northumbria University, Newcastle upon Tyne, NE1 8ST, United Kingdom; Children's Bone Marrow Transplant Unit, Ward 3, Great North Children Hospital, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, United Kingdom. Electronic address: zohreh.nademi@nuth.nhs.uk.
Molecular immunology.Mol Immunol.2013 Jun;54(2):227-32. doi: 10.1016/j.molimm.2012.12.007. Epub 2013 Jan 4.
The aetiology of Pigeon Fanciers' Lung (PFL) is believed to include immune complex formation between inhaled pigeon antigens and antibodies generated against them. However it is unclear why some fanciers are asymptomatic despite the presence of high levels of anti-avian antigen antibodies in their s
PMID 23291145

Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: Associations and functional implications.

Debnath M, Cannon DM, Venkatasubramanian G.SourceDepartment of Human Genetics, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore-560029, India. Electronic address: monozeet@gmail.com.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2013 Apr 5;42:49-62. doi: 10.1016/j.pnpbp.2012.07.009. Epub 2012 Jul 17.
Schizophrenia is a chronic debilitating neuropsychiatric disorder with a complex genetic contribution. Although multiple genetic, immunological and environmental factors are known to contribute to schizophrenia susceptibility, the underlying neurobiological mechanism(s) is yet to be established. The
PMID 22813842

Enhanced anti-tumor effects of HPV16E7(49-57)-based vaccine by combined immunization with poly(I:C) and oxygen-regulated protein 150.

Chen S, Ou R, Tang J, Deng X, Wu Y, van Velkinburgh JC, Ni B, Xu Y.SourceDepartment of Dermatovenereology, First Affiliated Hospital, Institute of Dermatovenereology, Wenzhou Medical College, Wenzhou 325000, China.
Cancer epidemiology.Cancer Epidemiol.2013 Apr;37(2):172-8. doi: 10.1016/j.canep.2012.10.005. Epub 2012 Nov 3.
Background: It is well known that both heat shock protein (HSP) and Toll-like receptor (TLR)3 agonist polyinosinic:polycytidylic acid (poly(I:C)) are capable of promoting the antigen-specific immune responses. In the current study, we assessed whether the anti-tumor effects of the HPV16E7(49-57)-bas
PMID 23127963

Japanese Journal

MHC matching improves engraftment of iPSC-derived neurons in non-human primates

Nature Communications 8, 2017-08-30
NAID 120006343783

滋賀医科大学医学部附属病院腫瘍センターにおけるがん薬物療法のレジメン審査と適正管理の動向に関する考察

滋賀医科大学雑誌 30(1), 102-107, 2017-07-03
NAID 120006330567

Exploration of the Conformational Dynamics of Major Histocompatibility Complex Molecules

Frontiers in Immunology 8, 2017-05-29
NAID 120006318865

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★リンクテーブル★

リンク元	「IC」「免疫複合体」「immunocomplex」「immunoconjugate」「antigen-antibody complex」
拡張検索	「immune complex rapidly progressive glomerulonephritis」「immune complex SVV」
関連記事	「complex」「immune」「complexed」「complexes」