- 関
- immune complex
WordNet
- complicated in structure; consisting of interconnected parts; "a complex set of variations based on a simple folk melody"; "a complex mass of diverse laws and customs"
- a compound described in terms of the central atom to which other atoms are bound or coordinated (同)coordination_compound
- a conceptual whole made up of complicated and related parts; "the complex of shopping malls, houses, and roads created a new town" (同)composite
- (psychoanalysis) a combination of emotions and impulses that have been rejected from awareness but still influence a persons behavior
- any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
- any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
PrepTutorEJDIC
- 『いくつかの部分から成る』,複合の,合成の / 『複雑な』,入りくんだ,こみいった(complicated) / 複合体,合成物 / コンプレックス,複合(抑圧されて心に残った複雑なしこり)
- 抗原(生物の体内にはいって免疫体を作る物質)
- 抗体,免疫体,抗毒素
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/06/05 10:32:01」(JST)
[Wiki en表示]
An immune complex, sometimes called an antigen-antibody complex, is a molecule formed from the integral binding of an antibody to a soluble antigen.[1] The bound antigen and antibody act as a unitary object, effectively an antigen of its own with a specific epitope. After an antigen-antibody reaction, the immune complexes can be subject to any of a number of responses, including complement deposition, opsonization,[2] phagocytosis, or processing by proteases. Red blood cells carrying CR1-receptors on their surface may bind C3b-coated immune complexes and transport them to phagocytes, mostly in liver and spleen, and return to the general circulation.
Immune complexes may themselves cause illness when they are deposited in organs, for example, in certain forms of vasculitis. This is the third form of hypersensitivity in the Gell-Coombs classification, called type III hypersensitivity.[3] Such hypersensitivity progressing to disease states produces the so-called immune complex diseases.
Immune complex deposition is a prominent feature of several autoimmune diseases, including systemic lupus erythematosus, cryoglobulinemia, rheumatoid arthritis, scleroderma and Sjögren's syndrome.[4][5]
References
- ^ Cush, John; Kavanaugh, Arthur; Stein, Charles (2005). Rheumatology: Diagnosis and Therapeutics. Lippincott Williams & Wilkins. p. 78. ISBN 9780781757324.
- ^ Goldsby, Richard (2002). Immunology. Macmillan. p. 381. ISBN 9780716749479.
- ^ Barret, James (1980). Basic Immunology and its Medical Application (2 ed.). St.Louis: The C.V. Mosby Company. ISBN 0-8016-0495-8.
- ^ Lawley, Thomas; Moustopoulos, Haralampos (1979). "Demonstration of Circulating Immune Complexes in Sjögren's Syndrome". Journal of Immunology (The American Association of Immunologists) 123 (3): 1382–7. PMID 469255.
- ^ Wallace, Daniel, ed. (2004). The New Sjogren's Syndrome Handbook. Oxford University Press. p. 68. ISBN 9780198038481.
Immunology: lymphocytic adaptive immune system and complement
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Lymphoid |
Antigens |
- Antigen presentation/Professional APCs: Dendritic cell
- Macrophage
- B cell
- Immunogen
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Antibodies |
- Antibody
- Monoclonal antibodies
- Polyclonal antibodies
- Autoantibody
- Microantibody
- Polyclonal B cell response
- Allotype
- Isotype
- Idiotype
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Immunity vs.
tolerance |
- action: Immunity
- Autoimmunity
- Alloimmunity
- Allergy
- Hypersensitivity
- Inflammation
- Cross-reactivity
- inaction: Tolerance
- Central
- Peripheral
- Clonal anergy
- Clonal deletion
- Tolerance in pregnancy
- Immunodeficiency
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Immunogenetics |
- Affinity maturation (Somatic hypermutation
- Clonal selection)
- V(D)J recombination
- Junctional diversity
- Immunoglobulin class switching
- MHC/HLA
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Lymphocytes |
- Cellular (T cell)
- Humoral (B cell)
- NK cell
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Substances |
- Cytokines
- Opsonin
- Cytolysin
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UpToDate Contents
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English Journal
- Rapid formation of cell-particle complexes via dielectrophoretic manipulation for the detection of surface antigens.
- Horii T1, Yamamoto M1, Yasukawa T2, Mizutani F3.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Nov 15;61:215-21. doi: 10.1016/j.bios.2014.05.019. Epub 2014 May 21.
- A rapid and simple method for the fabrication of the island patterns with particles and cells was applied to detect the presence of specific antigens on the cell surface. An upper interdigitated microband array (IDA) electrode was mounted on a lower substrate with the same design to fabricate a micr
- PMID 24892783
- Towards sensitive label-free immunosensing by means of turn-around point long period fiber gratings.
- Chiavaioli F1, Biswas P2, Trono C3, Bandyopadhyay S4, Giannetti A1, Tombelli S1, Basumallick N4, Dasgupta K4, Baldini F1.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Oct 15;60:305-10. doi: 10.1016/j.bios.2014.04.042. Epub 2014 May 2.
- Long period fiber gratings have been effectively used in the field of biochemical sensing since a few years. Compared to other well-known label-free optical approaches, long period gratings (LPGs) take advantage of the typical peculiarity of optical fibers. Coupling the propagating core mode with a
- PMID 24835405
- Cell surface antigen profiling using a novel type of antibody array immobilised to plasma ion-implanted polycarbonate.
- Main H1, Radenkovic J, Kosobrodova E, McKenzie D, Bilek M, Lendahl U.
- Cellular and molecular life sciences : CMLS.Cell Mol Life Sci.2014 Oct;71(19):3841-57. doi: 10.1007/s00018-014-1595-2. Epub 2014 Mar 13.
- To identify and sort out subpopulations of cells from more complex and heterogeneous assemblies of cells is important for many biomedical applications, and the development of cost- and labour-efficient techniques to accomplish this is warranted. In this report, we have developed a novel array-based
- PMID 24623559
Japanese Journal
- 特発性慢性寒冷凝集素症におけるカラム凝集法を用いた疾患活動性の評価
- 冨田 孝子,橋本 ひろみ,小西 和吾,藤本 ひろみ,森本 和秀,久保田 義則,平山 園子,南 陽介,大幡 真也,顔 邦男,杉本 健
- 日本輸血細胞治療学会誌 61(3), 422-426, 2015
- 【背景】カラム凝集法での裏検査の偽陽性反応の程度が特発性慢性寒冷凝集素症の疾患活動性を表すかどうかについて,症例の経過を観察することにより検討した.【症例】80歳,女性.貧血と胸部の紅斑を主訴とした.特発性慢性寒冷凝集素症の診断のもと,治療としてステロイド投与及びシクロスポリンの投与を行った.経過中に胸部の紅斑は一過性に減少し,再びやや増加した.補体値は一過性の増加を認めたが,この時期に寒冷凝集素 …
- NAID 130005088379
- 自動的にネットワークして成長する知能 : デジタル言語にもとづく個体と人類の知能のネットワーク要求解析
- 得丸 公明
- 電子情報通信学会技術研究報告. COMP, コンピュテーション 113(488), 1-8, 2014-03-03
- 言語と人類の誕生は,中石器時代の南アフリカのインド洋・大西洋沿岸地域で,今から7万7千年前にクリック子音という音素を獲得し,続いて6万6千年前に喉頭降下がおきて母音のアクセントを獲得し,モーラ(拍)性をもつ音節を獲得したことによる.音素は順列組み合わせによって,無限の単語(概念語)を作り出し,モーラは,アクセントがもつエネルギーのおかげで,すべての音節が相手に伝わることを保証し,文法が生まれた.言 …
- NAID 110009861237
- 松本 和也,宮田 隆志
- 高分子論文集 71(4), 125-142, 2014
- 刺激応答性ゲルは,温度やpHなどの外部環境変化に応答して体積変化を示すことから医療分野や環境分野に利用できるスマートマテリアルとして注目を集めている.最近では,疾病などのシグナルとなる生体分子を認識して体積変化する刺激応答性ゲル(生体分子応答性ゲル)も報告されるようになり,ドラッグデリバリーシステムや診断システムなどを構築するためのスマートバイオマテリアルとしての利用が期待されている.このような生 …
- NAID 130004489487
Related Links
- Aiming to determine if antigen-antibody complex formation - antigen blocking - interfered with detection of the heartworm antigen in cats using commercial assays, the study evaluated serum samples from six domestic cats confirmed ...
- The very first image is incorrectly depicting an antigen-antibody complex. And to say that antibodies are "poison" to foreign substances has no basis - they are involved in the immune response, but not as the actual thing that destroys ...
Related Pictures
★リンクテーブル★
[★]
- 英
- antigen-antibody complex
- 関
- 免疫複合体
[★]
可溶性抗原抗体複合体
[★]
- 関
- complexes、complicated、composite、conjugate、intricate
[★]
- 関
- hybrid、mixed lineage、mixed type、mixed-type
[★]
- 関
- complex、composite