STAT4転写因子
WordNet
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- (genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA
- a sound or television recording (e.g., from a broadcast to a tape recording)
- something written, especially copied from one medium to another, as a typewritten version of dictation (同)written text
PrepTutorEJDIC
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
- 〈U〉(…を)書き写す(書き直す)こと,(…の)転写,謄写《+of+名》 / 〈C〉写し(書き直し)[たもの] / 〈U〉〈C〉編曲[されたもの] / 〈U〉〈C〉(ラジオ・テレビの)録音(録画)
UpToDate Contents
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English Journal
- Triptolide Improves Diabetic Nephropathy by Regulating Th Cell Balance and Macrophage Infiltration in Rat Models of Diabetic Nephropathy.
- Guo H1, Pan C1, Chang B1, Wu X1, Guo J1, Zhou Y1, Liu H1, Zhu Z1, Chang B1, Chen L1.
- Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.Exp Clin Endocrinol Diabetes.2016 Jun;124(6):389-98. doi: 10.1055/s-0042-106083. Epub 2016 Jun 21.
- OBJECTIVE: To investigate the therapeutic effect of triptolide (TP) on diabetic nephropathy (DN) in addition to its influence on helper T lymphocytes (Th) cells and monocytes/macrophages in rat models of DN.METHODS: Diabetes was induced in rats by feeding them high-fat diets and administering low-do
- PMID 27328403
- RNA-Seq analysis reveals new evidence for inflammation-related changes in aged kidney.
- Park D1,2,3, Kim BC1,2, Kim CH4, Choi YJ1, Jeong HO1, Kim ME5, Lee JS5, Park MH1, Chung KW1, Kim DH1, Lee J1, Im DS1, Yoon S2,3, Lee S6, Yu BP7, Bhak J6, Chung HY1.
- Oncotarget.Oncotarget.2016 May 3. doi: 10.18632/oncotarget.9152. [Epub ahead of print]
- Age-related dysregulated inflammation plays an essential role as a major risk factor underlying the pathophysiological aging process. To better understand how inflammatory processes are related to aging at the molecular level, we sequenced the transcriptome of young and aged rat kidney using RNA-Seq
- PMID 27153548
- Involvement of transcription factor Oct-1 in the regulation of JAK-STAT signaling pathway in cells of Burkitt lymphoma.
- Pankratova EV1, Stepchenko AG2, Krylova ID3, Portseva TN2, Georgieva SG2.
- Doklady. Biochemistry and biophysics.Dokl Biochem Biophys.2016 May;468(1):229-31. doi: 10.1134/S1607672916030200. Epub 2016 Jul 15.
- We studied the role of transcription factor Oct-1 in the regulation of expression of genes of the JAK-STAT signaling pathway in the Namalwa Burkitt's lymphoma cell line. Overexpression of Oct-1 isoforms (Oct-1A, Oct-1L, and Oct-1X) causes a decrease in the activity of four genes involved in the JAK-
- PMID 27417729
Japanese Journal
- Thymic stromal lymphopoietin programs the "allergy code" in dendritic cells
- Arima Kazuhiko,Liu Yong-Jun
- Inflammation and Regeneration 32(1), 023-031, 2012
- … Whereas activation of nuclear factor κB (predominantly p50) drives DCs to produce OX40L to induce Th2 differentiation, the activation of signal transducer and activator of transcription 6 (STAT6) triggers DCs to secrete chemokines necessary for the recruitment of Th2 cells. … In addition, TSLP signaling limits the activation of STAT4 and interferon regulatory factor 8 (IRF8), which are essential factors for the production of the Th1-polarizing cytokine interleukin-12. …
- NAID 130004482289
- IRF5, STAT4, BLKと全身性エリテマトーデスをはじめとする膠原病との関連
- 土屋 尚之,伊東 郁恵,川崎 綾
- 日本臨床免疫学会会誌 = Japanese journal of clinical immunology 33(2), 57-65, 2010-04-28
- … トーデス(systemic lupus erythematosus, SLE)においては,1990年代から,HLA, C4, Fcγ受容体遺伝子群などの関連が確立されてきた.これに加え,2005年以降,ヨーロッパ系集団を中心とした大規模関連研究により,IRF5, STAT4, BLKなど,多くの新たな感受性遺伝子が報告されてきた.われわれは,これらの遺伝子について,日本人集団における関連を検討し,これらのいずれもが,日本人集団においてもSLEと有意に関連することから …
- NAID 10027753347
- Physical and functional interactions between STAT3 and ZIP kinase
- SATO Noriko,KAWAI Taro,SUGIYAMA Kenji,MUROMOTO Ryuta,IMOTO Seiyu,SEKINE Yuichi,ISHIDA Masato,AKIRA Shizuo,MATSUDA Tadashi
- International immunology 17(12), 1543-1552, 2005-12-01
- … Signal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic transcription factor that can be activated by cytokines and growth factors. … ZIPK specifically interacted with STAT3, and did not bind to STAT1, STAT4, STAT5a, STAT5b or STAT6. … Small interfering RNA-mediated reduction of ZIPK expression decreased leukemia inhibitory factor (LIF)- and IL-6-induced STAT3-dependent transcription. …
- NAID 120000969736
Related Links
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form ...
- "STAT4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). ... A signal transducer and activator of transcription that mediates cellular ...
Related Pictures
★リンクテーブル★
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- 英
- STAT4 transcription factor
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- 関
- actual、actually、in fact、in practice、indeed、practically
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- 関
- element、elementary、factorial、parameter
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- 関
- TF、transcriptional regulator、transcriptional regulatory element
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signal transducer and activator of transcription