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1. 凝固検査の臨床使用 clinical use of coagulation tests
2. 出血性素因を有する成人患者へのアプローチ approach to the adult patient with a bleeding diathesis
3. 出血症状を有する小児に対するアプローチ approach to the child with bleeding symptoms
4. 幼児および小児における静脈血栓症および血栓塞栓症の診断および治療 diagnosis and treatment of venous thrombosis and thromboembolism in infants and children
5. 後天性の凝固因子阻害物質 acquired inhibitors of coagulation

Lupus anticoagulant - performance of the tests as recommended by the latest ISTH guidelines.

Swadzba J, Iwaniec T, Pulka M, de Laat B, de Groot PG, Musial J.SourceDept. of Medicine, Jagiellonian University Medical College, Krakow, Poland Dept. of Clinical Chemistry and Haematology, University Medical Center, Utrecht Sanquin Research, Amsterdam Synapse, CARIM, Maastricht University Medical Center, Maastricht, The Netherlands.
Journal of thrombosis and haemostasis : JTH.J Thromb Haemost.2011 Jun 25. doi: 10.1111/j.1538-7836.2011.04420.x. [Epub ahead of print]
Lupus anticoagulant (LA) is clinically the most relevant among all antiphospholipid antibody tests. Recently, new guidelines for LA detection were published. The objective of this retrospective cohort study was to compare tests recommended under these guidelines with other methods used for LA detect
PMID 21707912

Evaluation of activated partial thromboplastin time (aPTT) reagents for application in biomedical diagnostic device development.

Dudek MM, Harris LF, Killard AJ.SourceBiomedical Diagnostics Institute, National Centre for Sensor Research, Dublin City University, Dublin, Ireland.
International journal of laboratory hematology.Int J Lab Hematol.2011 Jun;33(3):272-80. doi: 10.1111/j.1751-553X.2010.01283.x. Epub 2010 Dec 1.
INTRODUCTION: The most commonly used test for monitoring heparin therapy is the activated partial thromboplastin time (aPTT). The response of available aPTT reagents to heparin varies significantly. The aim of this study was to highlight the differences between aPTT reagents stored in a dried format
PMID 21118388

Anticardiolipin Antibodies by an Enzyme-Linked Immunosorbent Assay : Fundamental Studies on the Conditions for Antigen-Application and Specificity of the Assay

ICHIKAWA Yukinobu,KOBAYASHI Nobumasa,KAWADA Tsutomu,MORITA Kazuyuki,TOKUNAGA Masahito,UCHIYAMA Mitsuaki,SHIMIZU Hiroaki,MORIUCHI Junko,TAKAYA Masatoshi,WATANABE Katsuto,ARIMORI Shigeru
Tokai journal of experimental and clinical medicine 14(2), 103-112, 1989-04
… The aCL activity in our patients' samples was almost completely inhibited by pre-incubation of sera with either CL or phospholipid reagent for activated partial thromboplastin time (APTT). … Interestingly, the aCL activity of the lupus anticoagulant was negative, but aCL-positive samples were also absorbed by the reagent for APTT. …
NAID 110004700534

真弓武仁,長沢浩平,山内保生,内藤靖,草場公宏,仁保喜之,木村潤一郎
日本臨床免疫学会会誌 10(1), 78-84, 1987
systemic lupus erythematosus (SLE)におけるlupus anticoagulant (LA)の臨床的意義を解明するため, SLE 70例のLAを検索し,その臨床像ならびに検査成績を検討した. LA陽性例はSLE 70例中11例(16%)であった. LA陽性群ではLA陰性群に比較して,自然流産(p<0.01),脳梗塞(p<0.05)を発症する頻度が有意に高 …
NAID 130000850644