English Journal

Chiral pharmacokinetics of zaltoprofen in rats by HPLC with solid-phase extraction.

Chu VM, Kim KT, Kim SH, Lee W, Lee KC, Nguyen VL, Hoang VL, Lee YK, Park KR, Jung SH, Kang JS.SourceCollege of Pharmacy, Chungnam National University, Daejeon 305-764, Republic of Korea.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2012 Nov;70:567-73. doi: 10.1016/j.jpba.2012.05.019. Epub 2012 May 23.
We investigated the pharmacokinetic profile of (R)- and (S)-zaltoprofen (ZPF) in rats using rapid and selective liquid chromatography with solid-phase extraction (SPE). The ZPF enantiomers were extracted from a small volume of plasma (0.2 mL) by means of SPE using cartridges and were analyzed on a C
PMID 22703836

Novel strategy for the control of postoperative pain: long-lasting effect of an implanted analgesic hydrogel in a rat model of postoperative pain.

Araki Y, Kaibori M, Matsumura S, Kwon AH, Ito S.SourceDepartment of Surgery, Kansai Medical University, Osaka, Japan.
Anesthesia and analgesia.Anesth Analg.2012 Jun;114(6):1338-45. doi: 10.1213/ANE.0b013e31824b26a2. Epub 2012 May 3.
BACKGROUND: The administration of nonsteroidal anti-inflammatory drugs (NSAIDs) is the most common nonopioid analgesic currently used for postoperative pain management. We tested the sustained analgesic effect of ketoprofen emanating from a biodegradable gelatin hydrogel in a rat model of postoperat
PMID 22556212

[Therapeutic effects of Pyranoprofen on the mouse dry eye induced by topical medication of Benzalkonium Chloride].

He H, Liu ZG, Lin ZR, Liu XC, He H, Xiao QG.SourceEye Institute and Affiliated Xiamen Eye Center of Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Xiamen 361005, China; Department of Ophthalmology, the Second Affiliated Hospital of Nanhua University, Hengyang 421001, China.
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology.Zhonghua Yan Ke Za Zhi.2012 Jan;48(1):33-40.
OBJECTIVE: Randomized controlled experimental study to investigate the therapeutic effect and the possible mechanism of Pranoprofen on the recovery of dry eye induced by topical medication of Benzalkonium Chloride (BAC) in mouse.METHODS: It was an experimental study. Seventy BALB/c mice were treated
PMID 22490914

Japanese Journal

Oral analgesia by non-steroidal anti-inflammatory drug zaltoprofen to manage cystoscopy-related pain : A prospective study

KOMIYA Akira,ENDO Takumi,KOBAYASHI Masayuki,KIM Woojin,ARAKI Kazuhiro,NAYA Yukio,SUZUKI Hiroyoshi,TOBE Toyofusa,ICHIKAWA Tomohiko,FUSE Hideki
International journal of urology 16(11), 874-880, 2009-11-01
NAID 10025618461