WordNet

be oppressive or disheartening to (同)weigh on
to a lower intensity; "he slowly phased down the light until the stage was completely black"
soft fine feathers (同)down feather
(American football) a complete play to advance the football; "you have four downs to gain ten yards"
fine soft dense hair (as the fine short hair of cattle or deer or the wool of sheep or the undercoat of certain dogs) (同)pile
(usually plural) a rolling treeless highland with little soil
understood perfectly; "had his algebra problems down" (同)down pat, mastered
extending or moving from a higher to a lower place; "the down staircase"; "the downward course of the stream" (同)downward
spatially or metaphorically from a higher to a lower level or position; "dont fall down"; "rode the lift up and skied down"; "prices plunged downward" (同)downwards, downward, downwardly
cause to come or go down; "The policeman downed the heavily armed suspect"; "The mugger knocked down the old lady after she refused to hand over her wallet" (同)knock down, cut_down, push down, pull down
shoot at and force to come down; "the enemy landed several of our aircraft" (同)shoot down, land
away from a more central or a more northerly place; "was sent down to work at the regional office"; "worked down on the farm"; "came down for the wedding"; "flew down to Florida"
becoming progressively lower; "the down trend in the real estate market"
being or moving lower in position or less in some value; "lay face down"; "the moon is down"; "our team is down by a run"; "down by a pawn"; "the stock market is down today"
being put out by a strikeout; "two down in the bottom of the ninth"
bring down or defeat (an opponent)
from an earlier time; "the story was passed down from father to son"
in an inactive or inoperative state; "the factory went down during the strike"; "the computer went down again"
not functioning (temporarily or permanently); "we cant work because the computer is down"
paid in cash at time of purchase; "put ten dollars down on the necklace"
shut; "the shades were down"
travel or traverse (a distance); "This car does 150 miles per hour"; "We did 6 miles on our hike every day"
the syllable naming the first (tonic) note of any major scale in solmization (同)doh, ut
proceed or get along; "How is she doing in her new job?"; "How are you making out in graduate school?"; "Hes come a long way" (同)fare, make_out, come, get along
create or design, often in a certain way; "Do my room in blue"; "I did this piece in wood to express my love for the forest" (同)make
carry on or function; "We could do with a little more help around here" (同)manage
get (something) done; "I did my job" (同)perform
have a certain weight
determine the weight of; "The butcher weighed the chicken" (同)librate
to be oppressive or burdensome; "weigh heavily on the mind", "Something pressed on his mind" (同)press
English physician who first described Downs syndrome (1828-1896) (同)John L. H. Down

PrepTutorEJDIC

(高い所から)『下へ』,降りて,地面へ / (地理・地図上)南へ,下町へ;(風・流れなどが)『下(しも)手へ』;《英》(都会・大学から)地方へ,離れて / (価格・品質・温度などが)『下がって』,(数量・スピードなどが)少なく,減じて,(濃度が)薄く / (健康・風の勢いなどが)『衰えて』,気分が沈んで / (時代などが)下がって,…に至るまで / (身分・地位が)下がって / (紙面に)書き留めて,記録して / (頭金を)現金で,即金で / 最後まで,徹底的に / しっかりと,動けないように / (高い所から)…『を下がって』;…『に沿って』;…の向こうに / …の下流に / …以来 / 《名詞の前にのみ用いて》『下りの』,下への / 《名詞の前にのみ用いて》(列車・バスなどが)下りの / 《補語にのみ用いて》下に,下がって / 《補語にのみ用いて》弱まった,おさまった;落胆した,元気のない / 《補語にのみ用いて》(勝負で)負けて,すって / 《補語にのみ用いて》《おもに米話》(野球で)アウト / …‘を'打倒する,負かす,撃ち落とす / …‘を'飲み干す,飲み込む / 下り,下降 / 《複数形で》不運,逆境
(鳥の)綿毛,うぶ毛,下羽 / (植物・果実の表面の)柔らかい毛
なだらかな草原地,丘陵地帯(特にイングランド南部の小高い白亜質の草原地the Downsを言う)
《疑問文・否定文を作る》 / 《否定命令文を作る》 / 《助動詞とbe動詞のどちらも含まない文に用いて付加疑問を作る》 / 《強意語として》 / 《文》《助動詞とbe動詞のどちらも含まない文に用いて倒置文を作る》 / 《あいづちを打つ場合に》 / 《先行する動詞またはそれを含む述部の代用》 / 《so,nor,neitherで始まる簡略文で》 / …‘を'『する』,行う,果たす / 《通例have done,時にbe doneの形で》…‘を'『終える』,済ませる / …‘を'作る,作り出す / …‘を'『処理する』,整える,片付ける / 〈学課〉‘を'『勉強する』,専攻する / 〈利益・害など〉‘を'与える,もたらす / 〈人〉‘に'『役立つ』,用が足りる(serve) / …の速度で進む,距離を行く / …‘を'見物する / 〈劇〉‘を'上演する;…‘の'役を演じる / …の役目(仕事)をする / 《おもに英》…‘を'だます,かつぐ / 《話》…をへとへとにさせる / 『する』;活動する / 《通例have done,時にbe doneの形で》(…を)『終える』,済ます《+『with』+『名』》 / 〈事が〉『運ぶ』;〈人が〉暮らしていく,健康である / 〈物が〉(…に)『間に合う』,十分である;〈人が〉(…に)役に立つ,向く《+『for』+『名』》 / 《複数形で》すべきこと / 〈C〉《おもに英》大宴会,大パーティー / 〈C〉《英話》詐欺,ぺてん
ド(全音階の第1音)
…‘の'『重さを計る』 / 〈ある重さ〉‘を'『計量する』,計る / (…と比較して)…‘を'『検討する』,考慮する〈+名 against+名〉 / 『重さがある』,目方がかかる / (…にとって)『重要である』,(‥に)重要糸される〈+with+名〉

UpToDate Contents

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1. ダウン症：臨床的特徴および診断 down syndrome clinical features and diagnosis
2. ダウン症候群：出生前スクリーニングの概要 down syndrome overview of prenatal screening
3. Acute myeloid leukemia in children and adolescents
4. ダウン症：マネージメント down syndrome management
5. Transient myeloproliferative disorder of Down syndrome

English Journal

Nucleonic-resolution optical mass sensor based on a graphene nanoribbon quantum dot.

Bin W, Zhu KD.AbstractThe high frequency and ultrasmall mass of graphene make it an ideal material for ultrasensitive mass sensing. In this article, based on the all-optical technique, we propose a scheme of an optical mass sensor to weigh the mass of a single atom or molecule via a doubly clamped Z-shaped graphene nanoribbon (GNR). We use the detection of shifts in the resonance frequency of the Z-shaped GNR to determine the mass of an external particle landing on the GNR. The highly sensitive mass sensor proposed here can weigh particles down to the yoctogram and may eventually be enable to realize the mass measurement of nucleons.
Applied optics.Appl Opt.2013 Aug 10;52(23):5816-21. doi: 10.1364/AO.52.005816.
The high frequency and ultrasmall mass of graphene make it an ideal material for ultrasensitive mass sensing. In this article, based on the all-optical technique, we propose a scheme of an optical mass sensor to weigh the mass of a single atom or molecule via a doubly clamped Z-shaped graphene nanor
PMID 23938436

Obesity and respiratory infections: does excess adiposity weigh down host defense?

Mancuso P.SourceDepartment of Environmental Health Sciences and the Graduate Program in Immunology, 109 S Observatory Street, School of Public Health, University of Michigan, 6627 SPH1A, Ann Arbor, MI 48109-2029, USA. pmancuso@umich.edu
Pulmonary pharmacology & therapeutics.Pulm Pharmacol Ther.2013 Aug;26(4):412-9. doi: 10.1016/j.pupt.2012.04.006. Epub 2012 May 24.
The number of overweight and obese individuals has dramatically increased in the US and other developed nations during the past 30 years. While type II diabetes and cardiovascular disease are well recognized co-morbid conditions associated with obesity, recent reports have demonstrated a greater sev
PMID 22634305

The physical burdens of secrecy.

Slepian ML, Masicampo EJ, Toosi NR, Ambady N.SourceDepartment of Psychology, Tufts University, 490 Boston Avenue, Medford, MA 02155, USA. michael.slepian@tufts.edu
Journal of experimental psychology. General.J Exp Psychol Gen.2012 Nov;141(4):619-24. doi: 10.1037/a0027598. Epub 2012 Mar 5.
The present work examined whether secrets are experienced as physical burdens, thereby influencing perception and action. Four studies examined the behavior of people who harbored important secrets, such as secrets concerning infidelity and sexual orientation. People who recalled, were preoccupied w
PMID 22390267