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1. 肥満への遺伝的影響と病態生理genetic contribution and pathophysiology of obesity [show details]
… There are a number of single-gene defects associated with obesity and syndromes that include the clinical feature of obesity. An increase in body fat (both visceral and nonvisceral [subcutaneous]) requires …
2. 小児や青年の肥満の定義、疫学、病因definition epidemiology and etiology of obesity in children and adolescents [show details]
… separately. The term "obesity" refers to an excess of fat. However, the methods used to directly measure body fat are not available in daily practice. For this reason, obesity usually is assessed by the …
3. 成人の肥満：発生率、スクリーニング、および評価obesity in adults prevalence screening and evaluation [show details]
… mortality due to obesity. However, the relationship between percent body fat and BMI is different among different ethnic groups. In Caucasian, Hispanic, and black individuals, overweight is defined as a …
4. 肥満の小児や青年の臨床的評価clinical evaluation of the obese child and adolescent [show details]
… of body fat (concentrated in the interscapular area, face, neck, and trunk) may suggest Cushing syndrome, although this distribution of fat is also seen in physiologic obesity. Abdominal obesity (also …
5. 成人の肥満：疫学および危険因子obesity in adults etiology and risk factors [show details]
… increase in abdominal and visceral fat. Psychological factors are important in the development of obesity, although attempts to define a specific personality type associated with obesity have been unsuccessful …

English Journal

AMPK activation attenuates inflammatory response to reduce ambient PM-induced metabolic disorders in healthy and diabetic mice.

Pan K, Jiang S, Du X, Zeng X, Zhang J, Song L, Zhou J, Kan H, Sun Q, Xie Y, Zhao J.
Ecotoxicology and environmental safety. 2019 Sep;179()290-300.
Epidemiological and experimental studies have indicated that ambient fine particulate matter (PM) exposure is associated with the occurrence and development of metabolic disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the mechanism is not clear yet, and there are few studies
PMID 31071567

Gentiopicroside isolated from Gentiana scabra Bge. inhibits adipogenesis in 3T3-L1 cells and reduces body weight in diet-induced obese mice.

Choi RY, Nam SJ, Lee HI, Lee J, Leutou AS, Ri Ham J, Lee MK.
Bioorganic & medicinal chemistry letters. 2019 Jul;29(14)1699-1704.
Gentiopicroside is a major active component of the Gentiana scabra Bge., which is commonly used as herbal medicine for the treatment of inflammation in Asia. Gentiopicroside significantly down-regulated expression of key adipogenic transcription factors (PPARγ, C/EBPα, SREBP-1c) and dose-dependent
PMID 31130265

Short and long-term effects of bisphenol S (BPS) exposure during pregnancy and lactation on plasma lipids, hormones, and behavior in rats.

da Silva BS, Pietrobon CB, Bertasso IM, Lopes BP, Carvalho JC, Peixoto-Silva N, Santos TR, Claudio-Neto S, Manhães AC, Oliveira E, de Moura EG, Lisboa PC.
Environmental pollution (Barking, Essex : 1987). 2019 Jul;250()312-322.
Bisphenol S (BPS) has replaced bisphenol A (BPA), a known non-persistent endocrine disrupting chemical, in several products. Considering that little is known regarding BPS effects, especially during critical windows of ontogenetic development, and that BPA, which is quite similar to BPS, is know to
PMID 31003143

Japanese Journal

後腹膜鏡下摘除術を施行した特発性副腎血腫の1例 : 肥満に関する到達法の考察を中心に

吉野干城,谷口洋樹,永見太一,和氣功治,川上一雄,並河哲志,大沼秀行,児玉光史,安本博晃,椎名浩昭
西日本泌尿器科 = The Nishinihon journal of urology 81(1), 59-64, 2019-02
NAID 40021814140

虚血性心電図異常を見出す新しい体格指数の開発

松下由実,横山徹爾
栄養学雑誌 77(2), 39-45, 2019
【目的】IHD（虚血性心疾患）関連の心電図異常を見出す能力が高い，侵襲性のない新しい体格指数を作成することを目的とした。【方法】2004～2010年に人間ドックでCT検査を受けた12,628名を対象とした。IHD関連の心電図異常（心電図異常もしくは心筋梗塞現在治療中）を従属変数，身長，体重，ウエスト周囲長CT</s …
NAID 130007650310

日本疾患モデル学会記録

KOMATSU Ginga,NONOMURA Toru,SASAKI Mai,ISHIDA Yuki,ARAI Satoko,MIYAZAKI Toru
Experimental Animals 68(2), 147-158, 2019
… Because animal models for NAFLD are needed to investigate the precise pathogenesis, we aimed to establish a new mouse model employing mice deficient for apoptosis inhibitor of macrophage (AIM−/−), which exhibit accelerated lipid storage in the liver and high susceptibility to developing HCC in response to a high-fat diet (HFD). …
NAID 130007642990