Production of a low molecular weight heparin production using recombinant glycuronidase.
Su G1, Li L1, Huang H1, Zhong W2, Yu P3, Zhang F4, Linhardt RJ5.
Carbohydrate polymers.Carbohydr Polym.2015 Dec 10;134:151-7. doi: 10.1016/j.carbpol.2015.08.001. Epub 2015 Aug 6.
The Δ4,5 unsaturated uronate (4-deoxy-α-l-threo-hex-4-eno-pyranosyluronic acid) residue is produced through the depolymerization of heparin, heparosan, and heparan sulfate with heparin lyases. The recovery of unsaturated uronate containing products is necessary to prepare low molecular weight hepa
Uronate dehydrogenases catalyse the oxidation of uronic acids to aldaric acids, which represent 'top value-added chemicals' that have the potential to substitute petroleum-derived chemicals. The identification and annotation of three uronate dehydrogenases derived from Fulvimarina pelagi HTCC2506,
Carbohydrate polymers.Carbohydr Polym.2015 Mar 6;117:400-7. doi: 10.1016/j.carbpol.2014.09.079. Epub 2014 Oct 7.
An attractive strategy for ameliorating symptoms arising from the multi-faceted processes of excessive and/or continual inflammation would be to identify compounds able to interfere with multiple effectors of inflammation. The well-tolerated pharmaceutical, heparin, is capable of acting through seve
uronate. Definition from Wiktionary, the free dictionary. Jump to: navigation, search. [edit] English. [edit] Noun. uronate (plural uronates). (biochemistry) Any salt or ester of a uronic acid ...
In enzymology, an uronate dehydrogenase (EC 1.1.1.203) is an enzyme that catalyzes the chemical reaction. D-galacturonate + NAD+ + ... Other names in common use include uronate: NAD-oxidoreductase, and uronic acid dehydrogenase.