WordNet

a special situation; "this thing has got to end"; "it is a remarkable thing"
a separate and self-contained entity
an action; "how could you do such a thing?"
an artifact; "how does this thing work?"
an entity that is not named specifically; "I couldnt tell what the thing was"
any attribute or quality considered as having its own existence; "the thing I like about her is ..."
a persistent illogical feeling of desire or aversion; "he has a thing about seafood"; "she has a thing about him"
a special abstraction; "a thing of the spirit"; "things of the heart"
a special objective; "the thing is to stay in bounds"
a statement regarded as an object; "to say the same thing in other terms"; "how can you say such a thing?"
an event; "a funny thing happened on the way to the..."
meet at breast level; "The runner breasted the tape"
the part of an animals body that corresponds to a persons chest
either of two soft fleshy milk-secreting glandular organs on the chest of a woman (同)bosom, knocker, boob, tit, titty
the front of the trunk from the neck to the abdomen; "he beat his breast in anger" (同)chest
meat carved from the breast of a fowl (同)white_meat
an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm

PrepTutorEJDIC

〈C〉(形のある)『物』,物体;(生物に対しての)『無生物』 / 〈C〉(形のない)『もの』,事,事柄,でき事 / 《複数形で》事情,事態,状勢,状況 / 《複数形で》(すべての)事物,事柄 / 《通例 the~》(努力・活動などの)目的,目標 / 〈C〉衣服,衣類・《one's things》持ち物,所持品,身の回り品 / 《複数形で》道具,用具・〈C〉《親愛・哀れみ・軽べつなどの感情をこめて》人,者,やつ / 《the~》《話》(…の)流行《+in+名》
《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
『胸』,『胸部』;(服の)胸部 / 『乳房』,乳 / 《文》胸中,心紳 / …'を'胸に受ける,胸に受けて進む / …‘に'雄々しく立ち向かう
《前述の名詞または文脈でそれと分かる名詞に付けて》『その』,あの,名の / 《唯一の事物に付けて》 / 《方角・自然現象に付けて》 / 《用具・楽器・特定の病気などに付けて》 / 《修飾吾[句]を伴う名詞に付けて》 / 《単数普通名詞に付けて》(1)《種族全体》…『というもの』 / 《複数名詞または集合名詞に付けて》 / 《単位》『…につき;…単位[で]』 / 《身体の一部に付けて,所有格に代わる》 / 《形容詞に付けて》 / 《固有名詞に付けて》 / 《強意用法に》『随一の』,典型的な / 《「the+比較級,the+比較級」の形で》『…すればするほどそれだけ』 / 《比較級の前に》(…につれて,のために)『それだけ』,ますます

UpToDate Contents

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1. 乳房腫瘤の臨床症状および診断 clinical manifestations and diagnosis of a palpable breast mass
2. 良性乳房疾患の概要 overview of benign breast disease
3. 乳癌の臨床的特徴、診断および病期分類 clinical features diagnosis and staging of newly diagnosed breast cancer
4. 乳房の葉状腫瘍 phyllodes tumors of the breast
5. 新たに診断された非転移性乳癌の治療の概要 overview of the treatment of newly diagnosed non metastatic breast cancer

English Journal

Induction of thyroid neoplasm following plant medicine marine algae (sargassum): a rare case and review of the literature.

Zhu G, Musumeci F, Byrne P1.Author information 1Institute of Oncology of George Zhu, 422407, Beijing, China. sansan4240732@163.com.AbstractIn this study induction of neoplasm in thyroid gland of one postoperative patient with breast cancer was conducted by marine algae (also seaweed, sargassum), which is presented here. A 41-year-old women was diagnosed as her right breast cancer complicated with lymph node metastasis in her right axilla on February, 1999. In June 19, 1999 she was given the combination chemotherapy of vincristine, cyclophosphamide, 5-Fluorouracil and cinobufacini drugs due to two lymph nodes on her right superclavicular following radical mastectomy. During chemotherapy she was also taken the adjuvant treatment of traditional medicine. Traditional medicine consisted of seaweed plant drugs (containing iodine 362,400 ug/kg). As to intermittent maintance treatment the total dosage of seaweed herb was at least exceeded 500 gram. Induction of thyroid tumor (thumb size) was found in June, 2001. A thyroidectomy due to thyroma was successfully performed. Histologically there revealed thyroid tissue without the evidence of metastasis of breast cancer. She had a 5-year survivor. The data indicated oncogenic function of some traditional herbs, and further experience of traditional medicine in treating thyroid disease especially in thyroid cancer.
Current pharmaceutical biotechnology.Curr Pharm Biotechnol.2014 Oct;14(9):859-63.
In this study induction of neoplasm in thyroid gland of one postoperative patient with breast cancer was conducted by marine algae (also seaweed, sargassum), which is presented here. A 41-year-old women was diagnosed as her right breast cancer complicated with lymph node metastasis in her right axil
PMID 24433506

Immunohistochemical study of cyclooxygenase-2 in skin tumors.

Amirnia M1, Babaie-Ghazani A, Fakhrjou A, Khodaeiani E, Alikhah H, Naghavi-behzad M, Zarrintan A.Author information 1Department of Dermatology, Sina Hospital, Tabriz University of Medical Sciences , Tabriz , Iran.AbstractINTRODUCTION: Anti-cancerous effects of cyclooxygenase-2 (COX-2) inhibitors have been reported in different cancers. High expression of COX-2 has been demonstrated in various neoplasms such as colorectal, gastric, esophageal, breast, non-small cell lung cancers, and pre-neoplastic lesions such as colorectal adenomas and Barrett's esophagus.
The Journal of dermatological treatment.J Dermatolog Treat.2014 Oct;25(5):380-7. doi: 10.3109/09546634.2012.674191. Epub 2012 Jun 5.
INTRODUCTION: Anti-cancerous effects of cyclooxygenase-2 (COX-2) inhibitors have been reported in different cancers. High expression of COX-2 has been demonstrated in various neoplasms such as colorectal, gastric, esophageal, breast, non-small cell lung cancers, and pre-neoplastic lesions such as co
PMID 22667343

Structurally engineered anodic alumina nanotubes as nano-carriers for delivery of anticancer therapeutics.

Wang Y1, Santos A1, Kaur G1, Evdokiou A2, Losic D3.Author information 1School of Chemical Engineering, The University of Adelaide, Adelaide, SA 5005, Australia.2School of Medicine, Discipline of Surgery, The University of Adelaide, Adelaide, SA 5005, Australia.3School of Chemical Engineering, The University of Adelaide, Adelaide, SA 5005, Australia. Electronic address: dusan.losic@adelaide.edu.au.AbstractHere, we report a study on the biocompatibility, cell uptake and in vitro delivery of tumor necrosis factor-related apoptosis-inducing ligand (Apo2L/TRAIL) by new nano-carriers called anodic alumina nanotubes (AANTs) for potential cancer therapy. AANTs were electrochemically engineered by a unique pulse anodization process, which enables precise control of the nanotube geometry, and used here as nano-carriers for drug delivery. In vitro cytotoxicity and cell uptake of AANTs was assessed using MDA-MB231-TXSA human breast cancer cells and mouse RAW 264.7 macrophage cells. AANTs exhibited excellent biocompatibility in both cell lines over a time course of five days even at a maximum concentration of AANTs of 100 μgmL(-1). Transmission electron microscopy and fluorescence microscopy confirmed a significant uptake of AANTs by RAW 264.7 cells and breast cancer cells. AANTs loaded with the pro-apoptotic protein Apo2L/TRAIL showed exceptional loading capacity (104 ± 14.4 μgmg(-1) of AANTs) and demonstrated significant decrease in viability of MDA-MB231-TXSA cancer cells due to apoptosis induction. These results demonstrate that AANTs are promising nano-carriers for drug delivery applications.
Biomaterials.Biomaterials.2014 Jul;35(21):5517-26. doi: 10.1016/j.biomaterials.2014.03.059. Epub 2014 Apr 14.
Here, we report a study on the biocompatibility, cell uptake and in vitro delivery of tumor necrosis factor-related apoptosis-inducing ligand (Apo2L/TRAIL) by new nano-carriers called anodic alumina nanotubes (AANTs) for potential cancer therapy. AANTs were electrochemically engineered by a unique
PMID 24731710

Japanese Journal

Cisplatin (CDDP) triggers cell death of MCF-7 cells following disruption of intracellular calcium ([Ca²⁺]i) homeostasis

Al-Taweel Nawaf,Varghese Elizabeth,Florea Ana-Maria [他]
The
NAID 40020232249

In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.

Shimizu Yoichi,Temma Takashi,Hara Isao,Makino Akira,Kondo Naoya,Ozeki Ei-Ichi,Ono Masahiro,Saji Hideo
Cancer science 105(8), 1056-1062, 2014-08
… Membrane type-1 matrix metalloproteinase (MT1-MMP) is a protease activating MMP-2 that mediates cleavage of extracellular matrix components and plays pivotal roles in tumor migration, invasion and metastasis. … Because in vivo noninvasive imaging of MT1-MMP would be useful for tumor diagnosis, we developed a novel near-infrared (NIR) fluorescence probe that can be activated following interaction with MT1-MMP in vivo. …
NAID 120005474472

肺原発悪性黒色腫の1例

吉田秀一,稲木俊介,峯浦一貴,若木美佐,小山孝彦,小山田吉孝,加藤良一
気管支学 : 日本気管支研究会雑誌 36(4), 364-367, 2014-07-25
背景.肺原発悪性黒色腫の報告例は極めて少ない.症例.67歳女性.半年前から咳嗽・喘鳴が出現.1か月前より呼吸困難が出現し,右胸水貯留を指摘され当科を受診した.胸部CTでは右肺門に腫瘤性病変と右胸水,胸膜肥厚を認めた.気管支鏡検査では右中間幹を閉塞する茶褐色の腫瘍を認め,同部の生検および胸水検体より悪性黒色腫と診断された.FDG-PETでは,右胸郭内以外には左乳腺内に転移と思われる小病変を認める他は …
NAID 110009833216