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English Journal

Genistein attenuates monocrotaline-induced pulmonary arterial hypertension in rats by activating PI3K/Akt/eNOS signaling.

Zheng Z1, Yu S2, Zhang W2, Peng Y2, Pu M2, Kang T2, Zeng J3, Yu Y4, Li G5,6.
Histology and histopathology.Histol Histopathol.2017 Jan;32(1):35-41. Epub 2016 Apr 18.
INTRODUCTION: Phytoestrogen genistein may be useful to treat pulmonary arterial hypertension (PAH). However, its mechanism is still not clear. The aim of the present study was to confirm the therapeutic effects of phytoestrogen genistein on PAH in monocrotaline-induced rat model and to explore its m
PMID 27087006

Towards patient-specific modeling of mitral valve repair: 3D transesophageal echocardiography-derived parameter estimation.

Zhang F1, Kanik J2, Mansi T3, Voigt I3, Sharma P3, Ionasec RI3, Subrahmanyan L4, Lin BA4, Sugeng L4, Yuh D5, Comaniciu D3, Duncan J6.
Medical image analysis.Med Image Anal.2017 Jan;35:599-609. doi: 10.1016/j.media.2016.09.006. Epub 2016 Sep 27.
Transesophageal echocardiography (TEE) is routinely used to provide important qualitative and quantitative information regarding mitral regurgitation. Contemporary planning of surgical mitral valve repair, however, still relies heavily upon subjective predictions based on experience and intuition. W
PMID 27718462

Cardiovascular disease in patients with osteogenesis imperfecta - a nationwide, register-based cohort study.

Folkestad L1, Hald JD2, Gram J3, Langdahl BL4, Hermann AP5, Diederichsen AC6, Abrahamsen B7, Brixen K8.
International journal of cardiology.Int J Cardiol.2016 Dec 15;225:250-257. doi: 10.1016/j.ijcard.2016.09.107. Epub 2016 Sep 30.
BACKGROUND: Osteogenesis imperfecta (OI) is a hereditary connective tissue disease often due to mutations in genes coding for type 1 collagen. Collagen type 1 is important in the development of the heart and vasculature. Little is known about the risk of cardiovascular disease (CVD) in OI.OBJECTIVE:
PMID 27741483