WordNet
- experiencing or showing fear; "a fearful glance"; "fearful of criticism"
- extremely distressing; "fearful slum conditions"; "a frightful mistake" (同)frightful
- timid by nature or revealing timidity; "timorous little mouse"; "in a timorous tone"; "cast fearful glances at the large dog" (同)timorous, trepid
- large in number or quantity (especially of discourse); "she took copious notes"; "a subject of voluminous legislation" (同)voluminous
- very unpleasant
PrepTutorEJDIC
- (大きさ・量・強度などで)『ものすごい』,途方もない / 『恐ろしい』,ぞっとさせる / 非常にすばらしい(wonderful)
- 『恐ろしい』,こわい / 《補語にのみ用いて》心配して,気づかって / 恐ろしがる,心配そうな / 《おもに英話》たいへんな,ひどい
- 豊富な,多量の / (作家が)多作の
- 『恐ろしい』,ものすごい / 実に不快な,ひどく悪い / 《話》ひどい,つまらない
- 『恐ろしい』,怖い / 『ひどい』,すさまじい / 《話》ひどく悪い,不愉快な
- 恐ろしい
- 途方もなく;恐ろしく;とても,非常に
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/10/13 01:47:38」(JST)
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- 1. 早産児の長期的合併症 long term complications of the premature infant
- 2. 輸血によるHIV感染およびAIDS transfusion transmitted hiv infection and aids
- 3. HIV感染患者における計画的治療中断療法 structured treatment interruptions in the hiv infected patient
- 4. フェルティ症候群における薬物療法 drug therapy in feltys syndrome
- 5. 歯の解剖学的構造および発達 anatomy and development of the teeth
English Journal
- Design and validation of a fiber optic point probe instrument for therapy guidance and monitoring.
- Xie H1, Xie Z1, Mousavi M1, Bendsoe N2, Brydegaard M1, Axelsson J1, Andersson-Engels S1.Author information 1Lund University, Department of Physics, P.O. Box 118, SE-221 00 Lund, Sweden.2Skåne University Hospital, Department of Dermatology and Venereology, Lasarettsgatan 15, SE-221 85 Lund, Sweden.AbstractABSTRACT. Optical techniques for tissue diagnostics currently are experiencing tremendous growth in biomedical applications, mainly due to their noninvasive, inexpensive, and real-time functionality. Here, we demonstrate a hand-held fiber optic probe instrument based on fluorescence/reflectance spectroscopy for precise tumor delineation. It is mainly aimed for brain tumor resection guidance with clinical adaptation to minimize the disruption of the standard surgical workflow and is meant as a complement to the state-of-the-art fluorescence surgical microscopy technique. Multiple light sources with fast pulse modulation and detection enable precise quantification of protoporphyrin IX (PpIX), tissue optical properties, and ambient light suppression. Laboratory measurements show the system is insensitive to strong ambient light. Validation measurements of tissue phantoms using nonlinear least squares support vector machines (LS-SVM) regression analysis demonstrate an error of <5% for PpIX concentration ranging from 400 to 1000 nM, even in the presence of large variations in phantom optical properties. The mean error is 3% for reduced scattering coefficient and 5% for blood concentration. Diagnostic precision of 100% was obtained by LS-SVM classification for in vivo skin tumors with topically applied 5-aminolevulinic acid during photodynamic therapy. The probe could easily be generalized to other tissue types and fluorophores for therapy guidance and monitoring.
- Journal of biomedical optics.J Biomed Opt.2014 Jul 1;19(7):71408. doi: 10.1117/1.JBO.19.7.071408.
- ABSTRACT. Optical techniques for tissue diagnostics currently are experiencing tremendous growth in biomedical applications, mainly due to their noninvasive, inexpensive, and real-time functionality. Here, we demonstrate a hand-held fiber optic probe instrument based on fluorescence/reflectance spec
- PMID 24623193
- Physico-chemical properties and thermal stability of microcrystalline cellulose isolated from Alfa fibres.
- Trache D1, Donnot A2, Khimeche K3, Benelmir R2, Brosse N2.Author information 1UER Chimie appliquée, Ecole Militaire Polytechnique, BP 17, Alger, Algeria. Electronic address: djalaltrache@gmail.com.2LERMAB, Faculté des Sciences et Technologies, Université de Lorraine, Vandœuvre-lès-Nancy, France.3UER Chimie appliquée, Ecole Militaire Polytechnique, BP 17, Alger, Algeria.AbstractIn this study, microcrystalline cellulose (Alfa-MCC) was extracted from Alfa fibres using acid hydrolysis method. The molecular weight of the cellulose samples was determined by gel permeation chromatography. The crystallinities were studied by means of X-ray diffraction and solid state cross polarization magic angle spinning (13)C nuclear magnetic resonance spectroscopy, revealing that Alfa-MCC was more crystalline than the native cellulose isolated from Alfa fibres. The morphology of the celluloses was investigated using scanning electron microscopy, showing a compact structure and a rough surface. Furthermore, a good thermal stability was shown for Alfa-MCC. Based on these analyses, Alfa-MCC showed tremendous potential use as composites reinforcing agent, foods stabilizer and pharmaceutical additive.
- Carbohydrate polymers.Carbohydr Polym.2014 Apr 15;104:223-30. doi: 10.1016/j.carbpol.2014.01.058. Epub 2014 Jan 27.
- In this study, microcrystalline cellulose (Alfa-MCC) was extracted from Alfa fibres using acid hydrolysis method. The molecular weight of the cellulose samples was determined by gel permeation chromatography. The crystallinities were studied by means of X-ray diffraction and solid state cross polari
- PMID 24607181
- Landscape of the relationship between type 2 diabetes and coronary heart disease through an integrated gene network analysis.
- Dong C1, Tang L2, Liu Z2, Bu S3, Liu Q3, Wang Q3, Mai Y4, Wang DW5, Duan S6.Author information 1Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, Zhejiang, China. Electronic address: dongchangzheng@nbu.edu.cn.2Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, Zhejiang, China.3Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, Zhejiang, China; Diabetes Center, School of Medicine, Ningbo University, Ningbo, Zhejiang, China.4The Affiliated Hospital, Ningbo University, Ningbo, Zhejiang, China.5Institute of Hypertension and Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: dwwang@tjh.tjmu.edu.cn.6Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, Zhejiang, China; Diabetes Center, School of Medicine, Ningbo University, Ningbo, Zhejiang, China. Electronic address: duanshiwei@nbu.edu.cn.AbstractType 2 diabetes (T2D) and coronary artery disease (CAD) are closely related chronic diseases with high prevalence and morbidity. However, a comprehensive comparison of the two diseases is lacking. Recent genome-wide association studies (GWAS) have identified a handful of single nucleotide polymorphisms (SNPs) that are significantly associated with the risk of T2D and CAD. These most significant findings may help interpret the pathogenesis of T2D and CAD. However, tremendous results from these GWAS are ignored. Here we revisited the raw datasets of these GWAS and performed an integrated gene network analysis to unveil the relationship between T2D and CAD by combining multiple datasets including protein-protein interaction (PPI) database, publication libraries, and pathway datasets. Our results showed that majority of genes were involved in the first module (1122 genes in T2D and 895 in CAD). Four pathways were found to be common in both T2D and CAD, including regulation of actin cytoskeleton, calcium signaling pathway, MAPK signaling pathway and focal adhesion (all P<0.00001). MAX which was involved in small cell lung cancer pathway was a hub gene unique to T2D (OR=1.2, P=0.006) but not in CAD. In contrast, three hub genes including PLEKHG5 (T2D: OR=1, P=1; CAD: OR=1.12, P=0.006), TIAM1 (T2D: OR=1, P=1; CAD: OR=1.48, P=0.004) and AKAP13 (T2D: OR=1, P=1; CAD: OR=1.38, P=0.001) were hub genes unique to CAD. Moreover, for some hub genes (such as SMAD3) that were susceptible to both T2D and CAD, their associated polymorphisms were unique to each of the two diseases. Our findings might provide a landscape of the relationship between T2D and CAD.
- Gene.Gene.2014 Apr 10;539(1):30-6. doi: 10.1016/j.gene.2014.02.001. Epub 2014 Feb 5.
- Type 2 diabetes (T2D) and coronary artery disease (CAD) are closely related chronic diseases with high prevalence and morbidity. However, a comprehensive comparison of the two diseases is lacking. Recent genome-wide association studies (GWAS) have identified a handful of single nucleotide polymorphi
- PMID 24508273
Japanese Journal
- Acceleration of stable interface structure searching using a kriging approach
- Jpn. J. Appl. Phys. 55(4), 045502, 2016-03-07
- NAID 150000112197
- テーブルトップ型フェムト秒電子線回折法を用いた超高速構造ダイナミクスの観測
- Journal of the Vacuum Society of Japan 59(2), 40-51, 2016
- NAID 130005138323
- Controlled Magnetic Properties of Iron Oxide-Based Nanoparticles for Smart Therapy
- KONA Powder and Particle Journal 33(0), 33-47, 2016
- NAID 130005129084
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- tremendous 【形】 〔大きさや程度が〕とてつもなく大きい[激しい]【文例】【... - アルクがお届けする進化するオンライン英和・和英辞書データベース。一般的な単語や連語から、イディオム、専門用語、スラングまで幅広く収録。
- tre·men·dous (trĭ-mĕn′dəs) adj. 1. a. Extremely large in amount, extent, or size; enormous: a tremendous sum of money. See Synonyms at enormous. b. Very great in scope or importance: tremendous influence. 2. Remarkable ...
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★リンクテーブル★
| リンク元 | 「copious」「terrible」「恐ろしい」「fearful」「dreadful」 |
| 拡張検索 | 「tremendously」 |
「copious」
- adj.
- おびただしい、大量の
- 関
- abundance、abundant、abundantly、bulk、large amount、large dose、large scale、massive、massively、profuse、tremendous
「terrible」
「恐ろしい」
「fearful」
「dreadful」
- adj.
「tremendously」
- adv.