WordNet
- any of various controls or devices for regulating or controlling fluid flow, pressure, temperature, etc.
- an official responsible for control and supervision of a particular activity or area of public interest
- a materials capacity to conduct electricity; measured as the reciprocal of electrical resistance
PrepTutorEJDIC
- 取り締まり人;調整者 / 調整装置
- (熱・電気などの)伝導度
UpToDate Contents
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English Journal
- The future of CFTR modulating therapies for cystic fibrosis.
- Davies JC1.
- Current opinion in pulmonary medicine.Curr Opin Pulm Med.2015 Nov;21(6):579-84. doi: 10.1097/MCP.0000000000000211.
- PURPOSE OF REVIEW: Huge progress has been made over the last few years in the field of small molecule therapies targeting cystic fibrosis transmembrane conductance regulator (CFTR), the protein defective in patients with cystic fibrosis. This review describes the progress and areas of future researc
- PMID 26390337
- A spatial model of fluid recycling in the airways of the lung.
- Sharp K1, Crampin E2, Sneyd J3.
- Journal of theoretical biology.J Theor Biol.2015 Oct 7;382:198-215. doi: 10.1016/j.jtbi.2015.06.050. Epub 2015 Jul 10.
- The genetic disease cystic fibrosis (CF) is a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and results in viscous mucus and impaired mucociliary clearance leading to chronic recurring pulmonary infections. Although extensive experimental research has been conducte
- PMID 26169010
- The IP3 R Binding Protein Released with Inositol 1,4,5-Trisphosphate Is Expressed in Rodent Reproductive Tissue and Spermatozoa.
- Borth H1, Weber N1, Meyer D1, Wartenberg A1, Arlt E1, Zierler S1, Breit A1, Wennemuth G2, Gudermann T1, Boekhoff I1.
- Journal of cellular physiology.J Cell Physiol.2015 Oct 6. doi: 10.1002/jcp.25209. [Epub ahead of print]
- Besides its capacity to inhibit the 1,4,5-trisphosphate (IP3 ) receptor, the regulatory protein IRBIT (IP3 receptor-binding protein released with IP3 ) is also able to control the activity of numerous ion channels and electrolyte transporters and thereby creates an optimal electrolyte composition of
- PMID 26439876
Japanese Journal
- 『チャネル1分子を動画で見たい』 ABCトランスポーターCFTRチャネルのATP駆動性ゲーティング:静止画から動画へ
- 相馬 義郎,山下 隼人
- 日本薬理学雑誌 141(5), 230-234, 2013
- … ABCトランスポーターのメンバーであるCystic Fibrosis Transmembrane conductance Regulator(CFTR)は,呼吸器および消化管上皮の管腔側膜に発現して陰イオンチャネルとして機能し,分泌・吸収機能における中心的役割を果たしている.CFTRの機能不全は,白人種に多く見られる致死性遺伝疾患・嚢胞性線維症Cystic Fibrosis(CF)をはじめとし,慢性膵炎やCOPDなど多くの呼吸器および消化器疾患の …
- NAID 130003362558
- Activation of AMP-Activated Protein Kinase by a Plant-Derived Dihydroisosteviol in Human Intestinal Epithelial Cell
- Muanprasat Chatchai,Sirianant Lalida,Sawasvirojwong Sutthipong [他],Homvisasevongsa Sureeporn,Suksamrarn Apichart,Chatsudthipong Varanuj
- Biological and Pharmaceutical Bulletin 36(4), 522-528, 2013
- … Our previous study has shown that dihydroisosteviol (DHIS), a derivative of stevioside isolated from Stevia rebaudiana (Bertoni), inhibits cystic fibrosis transmembrane conductance regulator (CFTR)-mediated transepithelial chloride secretion across monolayers of human intestinal epithelial (T84) cells and prevents cholera toxin-induced intestinal fluid secretion in mouse closed loop models. …
- NAID 130003361395
- のう胞性線維症におけるトランスレーショナルリサーチ
Related Links
- The official name of this gene is “cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7).” CFTR is the gene's official symbol. The CFTR gene is also known by other names ...
- This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies ...
Related Pictures
★リンクテーブル★
[★]
- 英
- transmembrane conductance regulator
[★]
嚢胞性線維症膜貫通調節蛋白質
[★]
- 関
- permeability、permeabilize、permeable
[★]
- 関
- membrane-spanning、TM、transmembranous
[★]
- 関
- regulatory factor
[★]
- 関
- membrane conductance