- 関
- membrane conductance
WordNet
- a materials capacity to conduct electricity; measured as the reciprocal of electrical resistance
PrepTutorEJDIC
- (熱・電気などの)伝導度
UpToDate Contents
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English Journal
- Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing.
- Tang XX, Fok KL, Chen H, Chan KS, Tsang LL, Rowlands DK, Zhang XH, Da Dong J, Ruan YC, Jiang X, Yu SS, Chung YW, Chan HC.SourceEpithelial Cell Biology Research Center, School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, N.T., HKSAR, Hong Kong, China.
- Journal of cellular physiology.J Cell Physiol.2012 Dec;227(12):3887-94. doi: 10.1002/jcp.24101.
- The expression of cystic fibrosis transmembrane conductance regulator (CFTR) in lymphocytes has been reported for nearly two decades; however, its physiological role remains elusive. Here, we report that co-culture of lymphocytes with lung epithelial cell line, Calu-3, promotes epithelial HCO 3- p
- PMID 22552906
- Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator.
- Luciani A, Villella VR, Esposito S, Gavina M, Russo I, Silano M, Guido S, Pettoello-Mantovani M, Carnuccio R, Scholte B, De Matteis A, Maiuri MC, Raia V, Luini A, Kroemer G, Maiuri L.SourceEuropean Institute for Research in Cystic Fibrosis; San Raffaele Scientific Institute; Milan, Italy; Institute of Pediatrics; University of Foggia; Foggia, Italy.
- Autophagy.Autophagy.2012 Nov 1;8(11). [Epub ahead of print]
- Channel activators (potentiators) of cystic fibrosis (CF) transmembrane conductance regulator (CFTR), can be used for the treatment of the small subset of CF patients that carry plasma membrane-resident CFTR mutants. However, approximately 90% of CF patients carry the misfolded ΔF508-CFTR and are p
- PMID 22874563
Japanese Journal
- 『チャネル1分子を動画で見たい』 ABCトランスポーターCFTRチャネルのATP駆動性ゲーティング:静止画から動画へ
- 相馬 義郎,山下 隼人
- 日本薬理学雑誌 141(5), 230-234, 2013
- … ABCトランスポーターのメンバーであるCystic Fibrosis Transmembrane conductance Regulator(CFTR)は,呼吸器および消化管上皮の管腔側膜に発現して陰イオンチャネルとして機能し,分泌・吸収機能における中心的役割を果たしている.CFTRの機能不全は,白人種に多く見られる致死性遺伝疾患・嚢胞性線維症Cystic Fibrosis(CF)をはじめとし,慢性膵炎やCOPDなど多くの呼吸器および消化器疾患の病態への関与が示唆 …
- NAID 130003362558
- Activation of AMP-Activated Protein Kinase by a Plant-Derived Dihydroisosteviol in Human Intestinal Epithelial Cell
- , , [他], , ,
- Biological and Pharmaceutical Bulletin 36(4), 522-528, 2013
- … Our previous study has shown that dihydroisosteviol (DHIS), a derivative of stevioside isolated from Stevia rebaudiana (Bertoni), inhibits cystic fibrosis transmembrane conductance regulator (CFTR)-mediated transepithelial chloride secretion across monolayers of human intestinal epithelial (T84) cells and prevents cholera toxin-induced intestinal fluid secretion in mouse closed loop models. …
- NAID 130003361395
- のう胞性線維症におけるトランスレーショナルリサーチ
Related Links
- Cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that in humans is encoded by the CFTR gene. CFTR is an ABC transporter-class ion channel that transports chloride and thiocyanate ions across epithelial cell ...
- The official name of this gene is “cystic fibrosis transmembrane conductance regulator (ATP-binding cassette ... The CFTR gene provides instructions for making a protein called the cystic fibrosis transmembrane conductance regulator.
Related Pictures
★リンクテーブル★
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- 関
- transmembrane conductance
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嚢胞性線維症膜貫通調節蛋白質
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- 関
- permeability、permeabilize、permeable
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- 関
- membrane-spanning、TM、transmembranous