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1. 羊水量調節の生理学 physiology of amniotic fluid volume regulation
2. 子癇前症の病因 pathogenesis of preeclampsia
3. 天疱瘡の病因、臨床症状、および診断 pathogenesis clinical manifestations and diagnosis of pemphigus
4. 性器単純ヘルペスウイルス感染と妊娠 genital herpes simplex virus infection and pregnancy
5. 腎無形成の出生前診断 prenatal diagnosis of renal agenesis

Elevated DLL4 expression is correlated with VEGF and predicts poor prognosis of nasopharyngeal carcinoma.

Zhang JX, Cai MB, Wang XP, Duan LP, Shao Q, Tong ZT, Liao DZ, Li YY, Huang MY, Zeng YX, Shao JY.SourceState Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Medical oncology (Northwood, London, England).Med Oncol.2013 Mar;30(1):390. doi: 10.1007/s12032-012-0390-x. Epub 2012 Dec 30.
Delta-like ligand 4 (DLL4), one of the transmembranous Notch ligands, is upregulated at the site of tumor growth, particularly during tumor angiogenesis. Expression pattern of DLL4 in nasopharyngeal carcinoma (NPC) and the clinical and prognostic significance remain unclear. In this study, immunohis
PMID 23275120

Interleukin-15 receptor α expression in inflammatory bowel disease patients before and after normalization of inflammation with infliximab.

Perrier C, Arijs I, Staelens D, Breynaert C, Cleynen I, Covens K, Ferrante M, Van Assche G, Vermeire S, de Hertogh G, Schuit F, Rutgeerts P, Ceuppens JL.SourceDepartment of Gastroenterology, Translational Research Centre for Gastrointestinal Disorders (TARGID), KU Leuven, Leuven, Belgium. Clementine.Perrier@med.kuleuven.be
Immunology.Immunology.2013 Jan;138(1):47-56. doi: 10.1111/imm.12014.
Interleukin-15 (IL-15) is a pro-inflammatory cytokine thought to contribute to the inflammation in inflammatory bowel diseases (IBD). The specific receptor chain IL-15Rα can be expressed as a transmembranous signalling receptor, or can be cleaved by a disintegrin and metalloprotease domain 17 (ADAM
PMID 23039249

Sodium caprate transiently opens claudin-5-containing barriers at tight junctions of epithelial and endothelial cells.

Del Vecchio G, Tscheik C, Tenz K, Helms HC, Winkler L, Blasig R, Blasig IE.SourceLeibniz-Institut für Molekulare Pharmakologie, FMP, 13125 Berlin, Germany.
Molecular pharmaceutics.Mol Pharm.2012 Sep 4;9(9):2523-33. doi: 10.1021/mp3001414. Epub 2012 Aug 21.
Claudin-5 is a tight junction (TJ) protein which limits the diffusion of small hydrophilic molecules. Thus, it represents a potential pharmacological target to improve drug delivery to the tissues protected by claudin-5-dependent barriers. Sodium caprate is known as an absorption enhancer which open
PMID 22827574

A novel mutation in the RHD gane in Japanese individuals with weakD, encoding an amino acid change in the 11th transmembranous domain of the RhD protein