WordNet
- a soft thin (usually translucent) paper (同)tissue_paper
- part of an organism consisting of an aggregate of cells having a similar structure and function
PrepTutorEJDIC
- 〈U〉〈C〉(生物体の)『組織』 / 〈U〉〈C〉『薄織物』 / 〈U〉〈C〉水を吸収する柔らかな薄紙 / 〈C〉カーボンコピー用薄紙 / 〈C〉《a ~》(…を)織り交ぜて作ったもの《+of+名》 / =tissue paper
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/06/29 03:08:34」(JST)
[Wiki en表示]
Tissue remodeling is the reorganization or renovation of existing tissues. Tissue remodeling can be either physiological or pathological. The process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling. Macrophages repair wounds and remodel tissue by producing extracellular matrix and proteases to modify that matrix.[1]
A myocardial infarction induces tissue remodeling of the heart in a three-phase process: inflammation, proliferation, and maturation. Inflammation is characterized by massive necrosis in the infarcted area. Inflammatory cells clear the dead cells. In the proliferation phase, inflammatory cells die by apoptosis, being replaced by myofibroblasts which produce large amounts of collagen. In the maturation phase, myofibroblast numbers are reduced by apoptosis, allowing for infiltration by endothelial cells (for blood vessels) and cardiomyocytes (heart tissue cells). Usually, however, much of the tissue remodeling is pathological, resulting in a large amount of fibrous tissue.[2] By contrast, aerobic exercise can produce beneficial cardiac tissue remodeling in those suffering from left ventricular hypertrophy.[3]
Vascular remodeling refers to a compensatory change in blood vessel walls due to plaque growth. Vascular expansion is called positive remodeling, whereas vascular constriction is called negative remodeling.[4]
Tissue remodeling occurs in adipose tissue with increased body fat.[5] In obese subjects, this remodeling is often pathological, characterized by excessive inflammation and fibrosis.[6]
References
- ^ Lee BC, Lee J (2014). "Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance". Biochimica et Biophysica Acta. 1842 (3): 446–462. PMC 3800253 . PMID 23707515. doi:10.1016/j.bbadis.2013.05.017.
- ^ Talman V, Ruskoaho H (2016). "Cardiac fibrosis in myocardial infarction-from repair and remodeling to regeneration". Cell and Tissue Research. 365 (3): 563–581. PMC 5010608 . PMID 27324127. doi:10.1007/s00441-016-2431-9.
- ^ Fernandes T, Baraúna VG, Negrão CE, Phillips MI, Oliveira EM (2015). "Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs". American Journal of Physiology. Heart and Circulatory Physiology. 309 (4): H543–H552. PMC 4537939 . PMID 26071549. doi:10.1152/ajpheart.00899.2014.
- ^ Lee CS, Seo YH, Yang DJ, Kim KH, Park HW, Yuk HB, Lee MS, Kim WH, Kwon TG, Bae JH (2012). "Positive Vascular Remodeling in Culprit Coronary Lesion is Associated With Plaque Composition: An Intravascular Ultrasound-Virtual Histology Study". KOREAN CIRCULATION JOURNAL. 42 (11): 747–752. PMC 3518708 . PMID 23236326. doi:10.4070/kcj.2012.42.11.747.
- ^ Itoh M, Suganami T, Hachiya R, Ogawa Y (2011). "Adipose tissue remodeling as homeostatic inflammation". INTERNATIONAL JOURNAL OF INFLAMMATION. 2011: 720926. PMC 3132651 . PMID 21755030. doi:10.4061/2011/720926.
- ^ Choe SS, Huh JY, Hwang IJ, Kim JI, Kim JB (2016). "Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorder". Frontiers in Neuroendocrinology. 7: 30. PMC 4829583 . PMID 27148161. doi:10.3389/fendo.2016.00030.
UpToDate Contents
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English Journal
- Cellular and Molecular Mechanisms of Phenotypic Switch in Gastrointestinal Smooth Muscle.
- Scirocco A1, Matarrese P2,3, Carabotti M1, Ascione B2, Malorni W2,4, Severi C1.
- Journal of cellular physiology.J Cell Physiol.2016 Feb;231(2):295-302. doi: 10.1002/jcp.25105.
- As a general rule, smooth muscle cells (SMC) are able to switch from a contractile phenotype to a less mature synthetic phenotype. This switch is accompanied by a loss of differentiation with decreased expression of contractile markers, increased proliferation as well as the synthesis and the releas
- PMID 26206426
- Therapeutic Approaches to Histone Reprogramming in Retinal Degeneration.
- Berner AK1, Kleinman ME2.
- Advances in experimental medicine and biology.Adv Exp Med Biol.2016;854:39-44. doi: 10.1007/978-3-319-17121-0_6.
- Recent data have revealed epigenetic derangements and subsequent chromatin remodeling as a potent biologic switch for chronic inflammation and cell survival which are important therapeutic targets in the pathogenesis of several retinal degenerations. Histone deacetylases (HDACs) are a major componen
- PMID 26427391
Japanese Journal
- 音声外科術後のvoice rest至適期間および音声治療効果について
- Carvacrol inhibits osteoclastogenesis and negatively regulates the survival of mature osteoclasts
Related Links
- Definition, Protein involved in tissue remodeling. As an example the matrix- degrading plasminogen activators (PAs) and matrix metalloproteinases (MMPs) are general proteolytic enzyme systems which mediate tissue remodeling and tissue ...
Related Pictures
★リンクテーブル★
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- 関
- reassembly、reconstruct、reconstruction、remodel、remodeling、reorganization、restructure、tissue remodeling
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- 英
- tissue remodeling、remodeling、remodelling, tissue repair
- 関
- 再構築、再造形、リモデリング、組織リモデリング、組織再構築
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- 英
- tissue remodeling
- 関
- 組織修復、組織リモデリング
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- 英
- tissue remodeling
- 関
- 組織修復、組織再構築