1. a crystalline compound used in the form of a hydrochloride as a local anesthetic

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/04/23 13:28:51」(JST)

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English Journal

  • Benzonatate inhibition of voltage-gated sodium currents.
  • Evans MS1, Maglinger GB2, Fletcher AM3, Johnson SR4.
  • Neuropharmacology.Neuropharmacology.2016 Feb;101:179-87. doi: 10.1016/j.neuropharm.2015.09.020. Epub 2015 Sep 16.
  • Benzonatate was FDA-approved in 1958 as an antitussive. Its mechanism of action is thought to be anesthesia of vagal sensory nerve fibers that mediate cough. Vagal sensory neurons highly express the Nav1.7 subtype of voltage-gated sodium channels, and inhibition of this channel inhibits the cough re
  • PMID 26386152
  • Endotracheal Administration of Sufentanil and Tetracaine During Awake Fiberoptic Intubation.
  • Ji M1, Tao J, Cheng M, Wang Q.
  • American journal of therapeutics.Am J Ther.2016 Jan-Feb;23(1):e92-7. doi: 10.1097/MJT.0b013e31828fdb8c.
  • Combined use of local anesthetics and low-dose opioids enhances the effects of local anesthetics. This study aimed to evaluate the efficacy of combined administration of sufentanil and tetracaine through the cricothyroid membrane during awake nasal intubation using fiberoptic bronchoscopy in patient
  • PMID 23676347
  • Biphasic decay of the Ca transient results from increased sarcoplasmic reticulum Ca leak.
  • Sankaranarayanan R1, Li Y1, Greensmith DJ2, Eisner DA1, Venetucci L1,2,3.
  • The Journal of physiology.J Physiol.2015 Nov 5. doi: 10.1113/JP271473. [Epub ahead of print]
  • In heart failure reduction in Ca transient amplitude and contractile dysfunction can by caused by Ca leak through the sarcoplasmic reticulum (SR) Ca channel (Ryanodine Receptor, RyR) and/or decreased activity of the SR Ca ATPase (SERCA). We have characterized the effects of two forms of Ca leak (Ca-
  • PMID 26537441

Japanese Journal

  • Destabilization of phase-separated structures in local anesthetic-containing model biomembranes
  • 神経ブロックにより診断が遅れた症候性三叉神経痛の1例
  • 神経ブロックにより診断が遅れた症候性三叉神経痛の1例

拡張検索tetracaine hydrochloride



塩酸テトラカイン tetracaine hydrochloride

  • 局所麻酔薬;エステル型

tetracaine hydrochloride」

  [★] テトラカイン塩酸テトラカイン